Jun Tian

ORCID: 0000-0002-2511-9468
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About
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Research Areas
  • Genomics, phytochemicals, and oxidative stress
  • Mycotoxins in Agriculture and Food
  • Fungal and yeast genetics research
  • Autophagy in Disease and Therapy
  • Signaling Pathways in Disease
  • Helicobacter pylori-related gastroenterology studies
  • Tannin, Tannase and Anticancer Activities
  • Cancer, Hypoxia, and Metabolism
  • Cancer Research and Treatments
  • Medicinal Plants and Bioactive Compounds
  • Cancer Mechanisms and Therapy
  • Gut microbiota and health
  • Sunflower and Safflower Cultivation
  • Forensic Toxicology and Drug Analysis
  • Microbial Natural Products and Biosynthesis
  • Cancer, Lipids, and Metabolism
  • Vitamin C and Antioxidants Research
  • Reproductive tract infections research
  • Medical and Biological Ozone Research
  • Cannabis and Cannabinoid Research
  • Cancer-related Molecular Pathways
  • Polyamine Metabolism and Applications
  • Cardiac Ischemia and Reperfusion
  • Microbial Metabolism and Applications
  • Ferroptosis and cancer prognosis

Jiangsu Normal University
2020-2024

Chongqing Medical University
2023

Jiangsu Vocational College of Medicine
2022

Stomatology Hospital
2021

Sun Yat-sen University
2021

Beijing Technology and Business University
2020

Perillaldehyde (PAE), an essential oil in Perilla plants, serves as a safe flavor ingredient foods, and shows effectively antifungal activity. Reactive oxygen species (ROS) accumulation Aspergillus flavus plays critical role initiating metacaspase-dependent apoptosis. However, the reason for ROS A. is not yet clear. Using transcriptome sequencing of treated with different concentrations PAE, our data showed that might have been result inhibition energy metabolism less production reducing...

10.3390/ijms21041518 article EN International Journal of Molecular Sciences 2020-02-23

Vulvovaginal candidiasis (VVC) is one of the most frequent diseases induced by Candida albicans (C. albicans) during pregnancy, which results in enormous pain to women and their partners daily life. Perillaldehyde (PAE), a natural monoterpenoid, has significant anti-microbial, anti-inflammatory anti-oxidation effects. Reactive oxygen species (ROS) are key factors for host resist invasion fungi. However, excess ROS can cause additional damage independent pathogen itself, mechanism VVC not...

10.3390/antiox11020178 article EN cc-by Antioxidants 2022-01-18

Although colon (COAD) and rectal adenocarcinoma (READ) combined to refer colorectal cancer (CRC), substantial clinical evidence urged that CRC should be treated as two different cancers due compared with READ, COAD showed higher morbidity worse 5-year survival.

10.1016/j.jare.2023.07.007 article EN cc-by-nc-nd Journal of Advanced Research 2023-07-20

Aflatoxins (AFs) have always been regarded as the most effective carcinogens, posing a great threat to agriculture, food safety, and human health. Aspergillus flavus is major producer of aflatoxin contamination in crops. The prevention control A. continues be global problem. In this study, we demonstrated that cell-free culture filtrate oryzae non-aflatoxigenic can effectively inhibit production AFB1 growth reproduction flavus, indicating both strains secrete inhibitory compounds. Further...

10.3390/ijms21196994 article EN International Journal of Molecular Sciences 2020-09-23

Abstract Aflatoxins produced by Aspergillus flavus , a group of filamentous fungi widely distributed in nature as foodborne pathogens, are major threat to food safety. It is thus clear that inextricably linked the sector. Transcription factors enable correct expression genes at specific spatial and temporal levels, they constitute considerable proportion fungal genome sequence. Their presence particularly important for growth, secondary metabolism, stress response, pathogenic process . This...

10.1002/fsh3.12080 article EN cc-by Food Safety and Health 2024-11-18

Sepsis shock was associated with worse mortality than common sepsis caused by disseminated infection. The present study had shown that repression of adaptive immunity a characteristic rather sepsis, but the mechanism in which it exerted adverse reaction still need to be studied. In this study, we first employed weighted gene co-expression network analysis for acquiring key modules shock. Then, differentially expressed genes and transcription factors were screened module further function...

10.36468/pharmaceutical-sciences.1223 article EN cc-by-nc-sa Indian Journal of Pharmaceutical Sciences 2023-01-01
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