A5030609994- MicroRNA in disease regulation
- Metabolomics and Mass Spectrometry Studies
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Electromagnetic Scattering and Analysis
- Cancer-related Molecular Pathways
- Circular RNAs in diseases
- Microwave Imaging and Scattering Analysis
- Antenna Design and Analysis
- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Advanced Antenna and Metasurface Technologies
- Advanced Proteomics Techniques and Applications
- Peptidase Inhibition and Analysis
- Antenna Design and Optimization
- Lipid metabolism and biosynthesis
- Ferroptosis and cancer prognosis
- TGF-β signaling in diseases
- Sphingolipid Metabolism and Signaling
- Microwave and Dielectric Measurement Techniques
- Psoriasis: Treatment and Pathogenesis
- ICT Impact and Policies
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Treatments and Mutations
Rush University Medical Center
2013-2018
Rush University
2016
Midwestern University
2011-2012
University of Chicago
2006-2010
Cancer Genetics (United States)
2006
Duke Medical Center
2006
The Ohio State University
2006
Cancer Research Center
2006
University of Alabama at Birmingham
2006
Shanghai Jiao Tong University
1983
To analyze the prognostic impact of mutated KIT (mutKIT) in core-binding factor acute myeloid leukemia (AML) with inv(16)(p13q22) and t(8;21)(q22;q22).Sixty-one adults inv(16) 49 t(8;21), assigned to postremission therapy repetitive cycles higher dose cytarabine were analyzed for mutKIT exon 17 (mutKIT17) 8 (mutKIT8) by denaturing high-performance liquid chromatography direct sequencing at diagnosis. The median follow-up was 5.3 years.Among patients inv(16), 29.5% had (16% mutKIT17 13% sole...
Breast cancer is very common and highly fatal in women. Current non-invasive detection methods like mammograms are unsatisfactory. Lipidomics, a promising method, may serve as novel prognostic approach for breast high-risk patients.According the predictive model, combination of 15 lipid species had high diagnostic value. In training set, sensitivity, specificity, positive value (PPV) negative (NPV) these were 83.3%, 92.7%, 89.7%, 87.9%, respectively. The AUC set was 0.926 (95% CI...
Stable blood based miRNA species have allowed for the differentiation of patients with various types cancer. Therefore, specific blood-based might be considered as a methodology which could informative presence cancer potentially from multiple distinct organ sites. Recently, miR-21 has been identified an "oncomir" in tumors while miR-152 tumor suppressor. In this study, we investigated whether circulating and can used early detection lung (LuCa), colorectal carcinoma (CRC), breast (BrCa)...
Abstract BACKGROUND Prostate cancer (Pca) is a common malignancy that disproportionately affects African American men (AA). Recently there have been several genome‐wide association studies (GWAS) implicating new prostate risk loci along chromosomes 2, 3, 6, 7, 8, 10, 11, 12, 17, 19, and X in populations of European ancestry. Given the higher incidence mortality for AAs, differences allele frequencies haplotype structures between descent populations, it important to assess impact these...
Lipids play roles in membrane structure, energy storage, and signal transduction as well human cancers. Here we adopt lipidomics to identify plasma lipid markers for early screening detection of lung cancer.Using mass spectrometry, profiled 390 individual lipids using training validation strategy a total 346 samples from 199 NSCLC patients, including 113 adenocacinoma 86 squamous cell cancers (SqCC), 147 healthy controls.In the stage, found distinct groups that were significantly distributed...
Lipids are known to serve important roles in energy storage, membrane structure and signal transduction as well human cancers. In the present study, lipidomics was employed order identify plasma lipid markers for early detection of lung cancer. Mass spectrometry performed profile 390 individual lipids 44 samples obtained from a training discovery cohort, which included 22 patients with squamous cell carcinoma (SqCC) high-risk individuals. An additional cohort that individuals SqCC further...
Lung cancer is a major cause of cancer-related mortality worldwide, and around two-thirds patients have metastasis at diagnosis. Thus, detecting lung an early stage could reduce mortality. Aberrant levels circulating small non-coding RNAs (small ncRNAs) are potential diagnostic or prognostic markers for cancer. We aimed to identify plasma ncRNA pairs that be used screening detection adenocarcinoma (LAC).A panel seven pair ratios differentiate with LAC benign disease from high-risk controls...
N1-methyladenosine (m
Dyadic Green’s Functions for the calculation of electric arzcl magnetic fields, produced by swface current in a rectangular microwave heating cavity applicator, with stratified flat load, were derived expansion normalized mode vectors field. They used power distribution load Moment Method and optimization uniform heating. Satisfactory results obtained.
Griseofulvin, an oral nontoxic antifungal drug, has been reported to possess anticancer effect in human cancer cells, while the mechanisms are not completely understood.The aim of this study was investigate cytotoxic griseofulvin on K562 cells and understand its underlying molecular pathways.K562 were treated with at different concentrations for 24 hours, inhibition cell proliferation assessed by tetrazolium salt colorimetric assay. Apoptosis examining nuclear morphology quantifying...
Whole transcriptome shotgun sequencing (RNA-Seq) is a useful tool for analyzing the of biological sample. With appropriate statistical and bioinformatic processing, this platform capable identifying significant differences in gene expression within permits pathway network analyses to determine how these genes interact biologically. In study, we examined two lung adenocarcinoma cell lines (H358 A459) that were treated with transforming growth factor-β (TGF-β) as model induction...
(1982). The Development of Microwave Power Applications in China. Journal Power: Vol. 17, No. 1, pp. 11-15.
e22051 Background: Lung cancer is a severe health problem in Western countries and the most common cause of cancer-related death. Noninvasive methods are needed to improve current approaches detect non-small cell lung (NSCLC), circulating microRNA (miRNA) might be applied for early diagnosis this disease. Methods: 108 plasma samples from 55 stage NSCLC patients (stage I II) 53 high risk controls were collected at Rush University Medical Center. High was defined individuals aged 75 years,...
11114 Background: Lipids play roles in membrane structure, energy storage, and signal transduction as well lung cancer. Lipidomics, a new technology aims to measure all the lipids cell, has not been applied diagnostic test development for variety of cancer types. Here, we adopt lipidomics means identify plasma lipid markers early detection complement CT-based methods screening. Methods: Using mass spectrometry, profiled 390 individual training discovery cohort comprised cohorts that were...
The moment method is applied to calculate the near field around infinitely long scattered perfectly conducting and perfect dielectric cylinders of certain cross sections. An approximate formula for forward intensity case square cylinder derived.
The effect of a building on the radiation pattern two-element broadside array and an endfire is studied by moment method unimoment method. Buildings are made in similitude square rectangular conducting or dielectric cylinders infinite length.