A5068078315- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Personality Disorders and Psychopathology
- Perfectionism, Procrastination, Anxiety Studies
- Transcranial Magnetic Stimulation Studies
- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Obsessive-Compulsive Spectrum Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Psychotherapy Techniques and Applications
- Eating Disorders and Behaviors
- Personality Traits and Psychology
- Mental Health and Psychiatry
- Child and Adolescent Psychosocial and Emotional Development
- Bullying, Victimization, and Aggression
- Advanced Neuroimaging Techniques and Applications
- Suicide and Self-Harm Studies
- Dementia and Cognitive Impairment Research
- Emotions and Moral Behavior
- Takotsubo Cardiomyopathy and Associated Phenomena
- Advanced MRI Techniques and Applications
- Face Recognition and Perception
- Digital Mental Health Interventions
KU Leuven
2016-2025
VIB-KU Leuven Center for Brain & Disease Research
2021-2024
Huntsman (Belgium)
2010-2021
RELX Group (Netherlands)
2021
University Psychiatric Hospital
2016-2019
Statistics Belgium
2017
Leuven Institute for Fertility and Embryology
2017
University College London
2016
Zucker Hillside Hospital
2013
University of Leicester
2013
Using a daily process design, the present study examined relationships between momentary appraisals and emotional experience based on Smith Lazarus' (1993) theory of emotions (1993). Nine times day for 2 weeks, participants (N = 33, 23 women) recorded their positive (joy, love) 4 negative (anger, guilt, fear, sadness) core relational theme appraisal contents Lazarus hypothesized as corresponding to these emotions. A series multilevel modeling analyses found that were stronger than other...
Studies using retrospective self-report or proxies of nonsuicidal self-injury (NSSI) in the lab have shown that NSSI is often preceded by intense negative emotions and followed a decrease emotions/tension, suggesting an emotion regulation function NSSI. To investigate this more ecologically valid way, we used experience sampling methods to examine temporal relationship between behavior emotional experiences throughout day 30 inpatients currently staying psychiatric hospitals. Because...
Although a number of effective psychotherapeutic treatments have been developed for borderline personality disorder (BPD), little is known about the mechanisms change explaining effects these treatments.There increasing evidence that impairments in mentalizing or reflective functioning-the capacity to reflect on internal mental states self and others-are central feature BPD.To date, no study has directly investigated core assumption mentalization-based approach BPD, changes this are...
Objectives: There is little evidence for differences in response and speed of to electroconvulsive therapy (ECT) between patients with bipolar unipolar depressive disorder. In the only prospective study date, Daly et al. (Bipolar Disord 2001; 3: 95–104) found depression show more rapid clinical improvement require fewer treatments than patients. this study, treated ultra‐brief pulse ECT were compared. Methods: All (n = 64) participated a randomized trial comparing bifrontal at 1.5 times...
This study examined the relationship between psychotherapeutic process and outcome in 44 patients who completed hospitalization-based psychodynamic treatment for personality disorders. Using self-report interview ratings, was assessed terms of symptoms functioning, self object relations, felt safety, reflective functioning. Symptom measures were administered at intake, every 3 months during treatment, 12 follow-up. Personality collected end Piecewise Linear Growth Curve Analysis results...
Epigenetic regulation of imprinted genes during embryonic development is influenced by the prenatal environment. Our aim was to examine effect maternal emotional stress and cortisol levels pregnancy on methylation genes, insulin-like growth factor 2 (IGF2) guanine nucleotide-binding protein, alpha stimulating extra-large (GNASXL), using umbilical cord blood DNA. Maternal depressed mood (Edinburgh Depression Scale; EDS), pregnancy-related anxiety questionnaire (PRAQ) day profiles were...
There is ongoing concern about the possible negative impact of ECT on neurocognitive functioning in older patients. In this study, we aimed to characterize long-term cognitive effects patients with late-life depression, using an extensive neuropsychological battery.A total 110 aged 55 years and unipolar referred for were included. The test battery was assessed prior 6 months after last session.There no statistically significant group-level changes from baseline post-ECT any measurements....
Abstract Background Late-life depression (LLD) is characterized by medial temporal lobe (MTL) abnormalities. Although gray matter (GM) and white (WM) differences in LLD have been reported, few studies investigated them concurrently. Moreover, the impact of aetiological factors, such as neurodegenerative cerebrovascular burden, on tissue remains elusive. Methods This prospective cross-sectional study involved 72 participants, including 33 patients with (mean age 72.2 years, 23 female) 39...
ABSTRACT Introduction Cognitive side effects, such as memory loss, associated with electroconvulsive therapy (ECT) have been extensively studied. However, knowledge about (sub)acute confusional states during ECT is limited, particularly in older adults depression. Their incidence, recurrence, and co‐occurrence remain unclear. This study aimed to describe the co‐occurrence, clinical course of various subtypes ECT. Methods Data were derived from ‘Rivastigmine for ECT‐induced Adverse effects...
Many studies yield multivariate multiblock data, that is, multiple data blocks all involve the same set of variables (e.g., scores different groups subjects on variables). The question then rises whether processes underlie blocks. To explore structure such component analysis can be very useful. Specifically, 2 approaches are often applied: principal (PCA) each block separately and variants simultaneous (SCA) simultaneously. PCA approach yields a loading matrix for is thus not useful...
Despite large efforts to understand emotional instability in borderline personality disorder (BPD), it is still unclear exactly how this manifested the daily lives of people suffering from disorder. Building on theoretical and clinical observations BPD, we propose that BPD particularly consists occurrence strong changes between positive negative states 1 moment next, labeled switching. We tested proposal by means an experience sampling study which 30 patients 28 healthy controls reported...