- Stroke Rehabilitation and Recovery
- Botulinum Toxin and Related Neurological Disorders
- Cerebral Palsy and Movement Disorders
- Acute Ischemic Stroke Management
- Musculoskeletal pain and rehabilitation
- Action Observation and Synchronization
- EEG and Brain-Computer Interfaces
- Transcranial Magnetic Stimulation Studies
- Balance, Gait, and Falls Prevention
- Muscle activation and electromyography studies
- Neurological Disorders and Treatments
- Functional Brain Connectivity Studies
- Family and Disability Support Research
- Virtual Reality Applications and Impacts
- Dementia and Cognitive Impairment Research
- Infant Development and Preterm Care
- Motor Control and Adaptation
- Neuroinflammation and Neurodegeneration Mechanisms
- Children's Physical and Motor Development
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Forecasting Techniques and Applications
- Neuroscience and Music Perception
- Neurobiology of Language and Bilingualism
- Traumatic Brain Injury Research
Chang Gung University
2016-2025
Chang Gung Memorial Hospital
2009-2025
Linkou Chang Gung Memorial Hospital
2025
Memorial Hospital of South Bend
2025
National Taiwan University
2006-2024
Institute of Behavioral Sciences
2017-2024
Amazon (Germany)
2021
National Taiwan University Hospital
2007-2012
Cathay General Hospital
2009
National Cheng Kung University
2007
Background. The interpretation of the change scores Barthel Index (BI) in follow-up or outcome studies has been hampered by fact that its minimal clinically important difference (MCID) not determined. Objective. This article was written to establish MCID BI stroke patients. Methods. Both anchor-based and distribution-based methods were used MCID. In method, 43 inpatients participated a study designed determine using patients' global ratings activities daily living function on 15-point...
Background and Purpose— This study investigated compared the responsiveness validity of Fugl-Meyer Assessment (FMA), Action Research Arm Test (ARAT), Wolf Motor Function (WMFT) for patients after stroke rehabilitation. Methods— A total 57 with received 1 3 rehabilitation treatments weeks. At pretreatment posttreatment, outcome measures, as well Functional Independence Measure (FIM) external criterion, were administered. The standardized response mean (SRM) Wilcoxon signed rank test used to...
Objectives. This study aimed to establish the minimal detectable change (MDC) and clinically important differences (CID) of Wolf Motor Function Test (WMFT) in patients with stroke, assess proportions patients' scores exceeding MDC CID after stroke rehabilitation. Methods. A total 57 received 1 3 treatments for weeks underwent clinical assessments before treatment. The MDC, at 90% confidence (MDC 90 ), was calculated from standard error measurement indicate a real individual patients....
Objective: To compare the outcome of robot-assisted therapy with dose-matched active control by using accelerometers to study functional recovery in chronic stroke patients. Design: Prospective, randomized, controlled trial. Setting: Stroke units three medical centres. Subjects: Twenty patients post for a mean 22 months. Intervention: Robot-assisted ( n = 10) or 10). All received either these two therapies 90–105 minutes each day, 5 days per week, four weeks. Main measures: Outcome measures...
In this study, we compared the responsiveness and validity of Box Block Test (BBT), Nine-Hole Peg (NHPT), Action Research Arm (ARAT). We randomized 59 patients with stroke into one three rehabilitation treatments for 3 weeks. administered six outcome measures (BBT, NHPT, ARAT, Fugl-Meyer Assessment [FMA], Motor Activity Log [MAL], Stroke Impact Scale [SIS] hand function domain) pretreatment posttreatment. used standardized response mean (SRM) to examine Spearman rank correlation coefficient...
Spasticity is a major problem in patients with stroke and influences their activities of daily living, participation, quality life. The Modified Ashworth Scale widely used to assess spasticity. However, the responsiveness minimal clinically important differences have not been explored.This study aims examine stroke.Longitudinal six-month follow-up study.Rehabilitation wards tertiary hospital.One-hundred fifteen were recruited.All underwent assessment for upper extremity (flexors elbow,...
Background and Objectives. Robot-assisted therapy (RT) is a current promising intervention in stroke rehabilitation, but more research warranted for examining its efficacy the dose–benefit relation. The authors investigated effects of higher intensity versus lower RT on movements forearm pronation–supination wrist flexion–extension relative to conventional rehabilitation (CR) patients poststroke mean 21 months. Methods. In this pilot study, 18 with initial Fugl-Meyer Assessment (FMA) 37 44...
The increasing availability of robot-assisted therapy (RT), which provides quantifiable, reproducible, interactive, and intensive practice, holds promise for stroke rehabilitation, but data on its dose-response relation are scanty. This study used 2 different intensities RT to examine the treatment effects effect outcomes severity initial motor deficits.Fifty-four patients with were randomized a 4-week intervention higher-intensity RT, lower-intensity or control treatment. primary outcome,...
Lin K-C, Chung H-Y, Wu C-Y, Liu H-L, Hsieh Y-W, Chen I-H, C-L, Chuang L-L, J-S, Wai Y-Y: Constraint-induced therapy versus control intervention in patients with stroke: a functional magnetic resonance imaging study. Objective: This study compared the effects of distributed form constraint-induced motor recovery and brain reorganization after stroke. Design: A two-group randomized controlled trial pretreatment posttreatment measures was conducted. Thirteen stroke were randomly assigned to (n...
Robot-assisted therapy (RT) is a widely used intervention approach to enhance motor recovery in patients after stroke, but its effects on functional improvement remained uncertain. Neuromuscular electrical stimulation (NMES) one potential adjuvant RT that could directly activate the stimulated muscles and improve use of paretic hand. This was randomized, double-blind, sham-controlled study. Thirty-nine individuals with chronic stroke were randomly assigned combined NMES (RT + ES) or sham...
To investigate the treatment effects of bilateral robotic priming combined with task-oriented approach on motor impairment, disability, daily function, and quality life in patients subacute stroke.A randomized controlled trial.Occupational therapy clinics medical centers.Thirty-one stroke were recruited.Participants randomly assigned to receive (i.e., primed group) or alone unprimed for 90 minutes/day, 5 days/week 4 weeks. The group began technique by using a bimanual robot-aided...
Background . Action observation therapy and mirror therapy, two promising rehabilitation strategies, are aimed at enhancing the motor learning functional improvement of stroke patients through different patterns visual feedback observation. Objective This study investigated compared treatment effects action active control intervention on outcomes patients. Methods Twenty-one with subacute were recruited in this study. All randomly assigned to or for 3 weeks. Outcome measures conducted...
Abstract Background Accurate prediction of motor recovery after stroke is critical for treatment decisions and planning. Machine learning has been proposed to be a promising technique outcome because its high accuracy ability process large volumes data. It used predict acute recovery; however, whether machine would effective predicting rehabilitation outcomes in chronic patients common contemporary task-oriented interventions remains largely unexplored. This study aimed determine the...
Abstract Background and Objectives The Everyday Cognition Scale (ECog) is widely employed for the subjective rating of functional activities daily living in older adults. This study aimed to examine psychometric properties both informant-rated self-rated ECog Taiwanese individuals assess its applicability this context. Research Design Methods A total 1166 subjects, including adults (n = 583) their primary caregivers or family members 583), were recruited. Both assessments administered twice...
Objective: This study is aimed at testing the immediate and retained treatment efficacies of digital mirror therapy (DMT) action observation (DAOT) on clinical outcomes in chronic stroke patients, comparison with dose‐matched, active control rehabilitation (CR). Methods: Nineteen patients were randomly assigned to DMT, DAOT, or CR for 3 weeks. Outcome measures, including Fugl‐Meyer Assessment Upper Extremity (FMA‐UE), Chedoke Arm Hand Activity Inventory (CAHAI), Revised Nottingham Sensory...
This study examined the treatment efficacy of proximal-emphasized robotic rehabilitation by using InMotion ARM (P-IMT) versus distal-emphasized WRIST (D-IMT) in patients with stroke. A total 40 stroke completed study. They received P-IMT, D-IMT, or control (CT) for 20 training sessions. Primary outcomes were Fugl-Meyer Assessment (FMA) and Medical Research Council (MRC) scale. Secondary Motor Activity Log (MAL) wrist-worn accelerometers. The differences on distal FMA, MRC, MAL quality...
Abstract Background Robot‐assisted therapy (RT) is a promising intervention for stroke rehabilitation. RT hybridized with therapist‐mediated (eg, plus task‐specific or impairment‐oriented training) may possibly yield functionally relevant improvements. A comparative study of the different combination regimens needed. Objective To investigate efficacy combined training on motor function and quality life in patients chronic stroke. Design single‐blind, randomized study. Setting Two medical...
Abstract Background The timing of transcranial direct current stimulation (tDCS) with neurorehabilitation interventions may affect its modulatory effects. Motor function has been reported to be modulated by the tDCS; however, whether tDCS would also restoration daily and upper extremity motor control in stroke patients remains largely unexplored. Mirror therapy (MT) is a potentially effective approach for improving paretic arm patients. This study aimed determine MT influence treatment...