Chia‐Ling Chen

ORCID: 0000-0003-0566-1716
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About
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Research Areas
  • Cerebral Palsy and Movement Disorders
  • Stroke Rehabilitation and Recovery
  • Botulinum Toxin and Related Neurological Disorders
  • Family and Disability Support Research
  • Infant Development and Preterm Care
  • Musculoskeletal pain and rehabilitation
  • Transcranial Magnetic Stimulation Studies
  • Muscle activation and electromyography studies
  • Children's Physical and Motor Development
  • Balance, Gait, and Falls Prevention
  • Acute Ischemic Stroke Management
  • Assistive Technology in Communication and Mobility
  • HIV/AIDS Research and Interventions
  • Child Nutrition and Feeding Issues
  • Carbon Nanotubes in Composites
  • Autism Spectrum Disorder Research
  • Neuroscience and Neural Engineering
  • Neural and Behavioral Psychology Studies
  • EEG and Brain-Computer Interfaces
  • Attention Deficit Hyperactivity Disorder
  • HIV, Drug Use, Sexual Risk
  • Gaze Tracking and Assistive Technology
  • Genetics and Neurodevelopmental Disorders
  • Mechanical and Optical Resonators
  • Inclusion and Disability in Education and Sport

Chang Gung Memorial Hospital
2016-2025

Chang Gung University
2016-2025

Memorial Hospital of South Bend
2007-2025

Taipei Tzu Chi Hospital
2025

Linkou Chang Gung Memorial Hospital
2010-2024

Taipei Medical University
2014-2023

National Taiwan University
2010-2021

National Taiwan University Hospital
2009-2021

Ministry of Health and Welfare
2021

Taoyuan Chang Gung Memorial Hospital
2009-2020

Parylene-C, which is traditionally used to coat implantable devices, has emerged as a promising material generate miniaturized devices due its unique mechanical properties and inertness. In this paper we compared the surface cell protein compatibility of parylene-C relative other commonly BioMEMS materials. We evaluated hydrophobicity roughness these results those tissue culture-treated polystyrene, poly(dimethylsiloxane) (PDMS), glass. also treated PDMS with air plasma, coated surfaces...

10.1021/la7017049 article EN Langmuir 2007-10-04

Background and Purpose— This study investigated compared the responsiveness validity of Fugl-Meyer Assessment (FMA), Action Research Arm Test (ARAT), Wolf Motor Function (WMFT) for patients after stroke rehabilitation. Methods— A total 57 with received 1 3 rehabilitation treatments weeks. At pretreatment posttreatment, outcome measures, as well Functional Independence Measure (FIM) external criterion, were administered. The standardized response mean (SRM) Wilcoxon signed rank test used to...

10.1161/strokeaha.108.530584 article EN Stroke 2009-02-20

We report a technique to characterize adhesion of monolayered/multilayered graphene sheets on silicon wafer. Nanoparticles trapped at graphene-silicon interface act as point wedges support axisymmetric blisters. Local strength is found by measuring the particle height and blister radius using scanning electron microscope. Adhesion energy typical measured be 151±28 mJ/m2. The proposed method our measurements provide insights in fabrication reliability...

10.1063/1.3294960 article EN Journal of Applied Physics 2010-01-15

Objectives. This study aimed to establish the minimal detectable change (MDC) and clinically important differences (CID) of Wolf Motor Function Test (WMFT) in patients with stroke, assess proportions patients' scores exceeding MDC CID after stroke rehabilitation. Methods. A total 57 received 1 3 treatments for weeks underwent clinical assessments before treatment. The MDC, at 90% confidence (MDC 90 ), was calculated from standard error measurement indicate a real individual patients....

10.1177/1545968308331144 article EN Neurorehabilitation and neural repair 2009-03-16

Spasticity is a major problem in patients with stroke and influences their activities of daily living, participation, quality life. The Modified Ashworth Scale widely used to assess spasticity. However, the responsiveness minimal clinically important differences have not been explored.This study aims examine stroke.Longitudinal six-month follow-up study.Rehabilitation wards tertiary hospital.One-hundred fifteen were recruited.All underwent assessment for upper extremity (flexors elbow,...

10.23736/s1973-9087.19.05545-x article EN European Journal of Physical and Rehabilitation Medicine 2020-01-01

Gait patterns vary among stroke patients. This study attempted to discover gait performance with compensatory adaptations in patients different degrees of motor recovery.Data were gathered from 35 and 15 healthy subjects. recovery assessed 6 mos after stroke. Stroke further divided into poor good groups. The walking velocity was correlated Brunnström's stages, the temporal stride motion variables two groups compared.Walking positively stages proximal lower limb. group displayed slower...

10.1097/01.phm.0000098040.13355.b5 article EN American Journal of Physical Medicine & Rehabilitation 2003-11-14

To describe the characteristics of leg muscle activation patterns in hemiplegic stroke patients during movement rising from a chair and to determine differences between fallers nonfallers.Subjects stood up an armless at comfortable, self-paced speed. Leg time sit-to-stand were analyzed using multichannel surface electromyography force platform. The nonfallers compared.The mean onset activity affected limbs was markedly delayed for tibialis anterior earlier soleus muscle. side exhibited wide...

10.1097/01.phm.0000104665.34557.56 article EN American Journal of Physical Medicine & Rehabilitation 2003-12-25

Background. Most studies of bilateral arm training (BAT) did not employ a randomized controlled trial design and involved very limited functional tasks. Objective . Compare the effects BAT with control intervention (CI) on motor performance upper extremity also gains in patients chronic stroke. Methods. This 2-group pretreatment posttreatment measures enrolled 33 stroke (mean age = 53.85 years) 6 to 67 months after onset first They received either program concentrating both extremities...

10.1177/1545968309345268 article EN Neurorehabilitation and neural repair 2009-09-03

Improving HRQOL is the desired outcome for patients with stroke undergoing inpatient rehabilitation services. This study aimed to comprehensively identify potential health-related quality of life (HRQOL) predictors in within first year after stroke; thus far, such an investigation has not been conducted.We enrolled 119 (88 males, 31 females) stroke, and examined 12 predictors: age, sex, type, side, duration onset, cognition (Mini-Mental State Examination; MMSE), depression (Beck Depression...

10.1186/s12955-015-0314-5 article EN cc-by Health and Quality of Life Outcomes 2015-08-04

Intermittent theta burst stimulation (iTBS) is a form of repetitive transcranial that has been used to enhance upper limb (UL) motor recovery. However, only limited studies have examined its efficacy in patients with chronic stroke and therefore it remains controversial. This was randomized controlled trial enrolled from rehabilitation department. Twenty-two first-ever unilateral cerebral stroke, aged 30–70 years, were randomly assigned the iTBS or control group. All received 1 session per...

10.1186/s12883-019-1302-x article EN cc-by BMC Neurology 2019-04-25

To assess the balance function of hemiplegic stroke patients and to investigate whether visual feedback rhythmic weight-shift training following acute can decrease falls among with stroke.A prospective study, using a Balance Master.Hospital-based rehabilitation units.Fifty-two (28 in group 24 control group).Conventional programme plus training. Training effect was evaluated by assessing static dynamic performance as well comparing occurrence groups at six-month follow-up.Occurrence falls;...

10.1191/0269215504cr778oa article EN Clinical Rehabilitation 2004-11-01

Autophagy is regulated for IFN-gamma-mediated antimicrobial efficacy; however, its molecular effects IFN-gamma signaling are largely unknown. Here, we show that autophagy facilitates IFN-gamma-activated Jak2-STAT1. induces in wild-type but not protein 5 (Atg5(-/-))-deficient mouse embryonic fibroblasts (MEFs), and, autophagy-dependently, IFN regulatory factor 1 and cellular inflammatory responses. Pharmacologically inhibiting using 3-methyladenine, a known inhibitor of class III...

10.1074/jbc.m110.133355 article EN cc-by Journal of Biological Chemistry 2010-07-01

Lin K-C, Chung H-Y, Wu C-Y, Liu H-L, Hsieh Y-W, Chen I-H, C-L, Chuang L-L, J-S, Wai Y-Y: Constraint-induced therapy versus control intervention in patients with stroke: a functional magnetic resonance imaging study. Objective: This study compared the effects of distributed form constraint-induced motor recovery and brain reorganization after stroke. Design: A two-group randomized controlled trial pretreatment posttreatment measures was conducted. Thirteen stroke were randomly assigned to (n...

10.1097/phm.0b013e3181cf1c78 article EN American Journal of Physical Medicine & Rehabilitation 2010-02-12

This study examined the treatment efficacy of proximal-emphasized robotic rehabilitation by using InMotion ARM (P-IMT) versus distal-emphasized WRIST (D-IMT) in patients with stroke. A total 40 stroke completed study. They received P-IMT, D-IMT, or control (CT) for 20 training sessions. Primary outcomes were Fugl-Meyer Assessment (FMA) and Medical Research Council (MRC) scale. Secondary Motor Activity Log (MAL) wrist-worn accelerometers. The differences on distal FMA, MRC, MAL quality...

10.1038/s41598-018-20330-3 article EN cc-by Scientific Reports 2018-01-26
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