A5100665051- Cerebral Palsy and Movement Disorders
- Family and Disability Support Research
- Infant Development and Preterm Care
- Epilepsy research and treatment
- Functional Brain Connectivity Studies
- Pharmacological Effects and Toxicity Studies
- Stroke Rehabilitation and Recovery
- Neuroscience and Neuropharmacology Research
- Children's Physical and Motor Development
- Assistive Technology in Communication and Mobility
- Magnesium Alloys: Properties and Applications
- Ubiquitin and proteasome pathways
- Cancer-related molecular mechanisms research
- Balance, Gait, and Falls Prevention
- Shoulder Injury and Treatment
- Fungal and yeast genetics research
- Aluminum Alloys Composites Properties
- Aluminum Alloy Microstructure Properties
- Musculoskeletal pain and rehabilitation
- RNA modifications and cancer
- Cancer-related gene regulation
- EEG and Brain-Computer Interfaces
- Obsessive-Compulsive Spectrum Disorders
- Bacterial Infections and Vaccines
- MicroRNA in disease regulation
Chang Gung University
2013-2025
North University of China
2025
Sichuan University
2014-2024
West China Hospital of Sichuan University
2017-2024
Gansu Academy of Agricultural Sciences
2024
First Affiliated Hospital of Gannan Medical University
2024
Nanchang University
2022-2023
Gannan Medical University
2022-2023
First Affiliated Hospital of Nanchang University
2022-2023
Changhai Hospital
2019-2023
Liao H-F, Liu Y-C, W-Y, Lin Y-T. Effectiveness of loaded sit-to-stand resistance exercise for children with mild spastic diplegia: a randomized clinical trial.ObjectiveTo investigate effectiveness functional strengthening program, the (STS) exercise, cerebral palsy (CP).DesignA single-blind, block design.SettingSTS exercises were carried out at children's homes.ParticipantsTwenty (12 boys, 8 girls; age range, 5−12y) diplegia CP and classified by Gross Motor Function Classification System as...
This study investigates the effects of pediatric aquatic therapy on motor function, enjoyment, activities daily living, and health-related quality life for children with spastic cerebral palsy various severities. Children were assigned to a group (n = 11; mean age 85.0 ± 33.1 months; male : female 4 7) or control 13; 87.6 34.0 9 4). The statistic results indicate that had greater average 66-item Gross Motor Function Measure following intervention than (η 2 0.308, P .007), even Classification...
Background: Recent studies have shown that circulating long noncoding RNAs (lncRNAs) could be stably detectable in the blood of cancer patients and play important roles diagnosis many different cancers. However, value lncRNAs pancreatic (PC) has not been fully explored. Methods: Eleven PC-related were selected by analyzing bioinformatics databases. The expression levels further analyzed a small set plasma samples from training group including 30 noncancer (15 healthy 15 chronic pancreatitis...
// Kathleen M. Capaccione 1,2 , Xuehui Hong 2,3 Katherine Morgan Wenyu Liu 2 Michael J. Bishop 4 LianXin 3 Elke Markert 2,5 Malik Deen 6 Christine Minerowicz Joseph R. Bertino 5 Thaddeus Allen and Sharon Pine 1,2,5 1 Department of Pharmacology, Rutgers Graduate School Biomedical Science, Piscataway, New Jersey Cancer Institute Jersey, Brunswick, Surgery, The First Affiliated Hospital Harbin Medical University, Harbin, China G.W. Hooper Research Foundation, University California, San...
Abstract Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional multicentre structural MRI dataset 696 people with epilepsy 118 control subjects. We an innovative machine-learning algorithm, Subtype Stage Inference, to develop novel data-driven disease taxonomy, whereby subtypes correspond distinct patterns spatiotemporal progression brain atrophy.In discovery...
Abstract Objective Several antiseizure medications (ASMs) have been approved for the treatment of focal epilepsy. However, there is a paucity evidence on direct comparison ASMs. We evaluated comparative efficacy and safety all add‐on ASMs epilepsy using network meta‐analysis. Methods Data through extensive literature search was retrieved from PubMed, Embase, Cochrane, ClinicalTrial.gov databases predefined terms inception March 2023. PRISMA reporting guidelines (CRD42023403450) were followed...
SOX9 encodes a transcription factor that governs cell fate specification throughout development and tissue homeostasis. Elevated is implicated in the genesis progression of human tumors by increasing proliferation epithelial-mesenchymal transition. We found response to UV irradiation or genotoxic chemotherapeutics, actively degraded various cancer types normal epithelial cells, through pathway independent p53, ATM, ATR DNA-PK. phosphorylated GSK3β, facilitating binding F-box protein FBW7α,...
Cyclotides are plant-derived peptides with complex structures shaped by their head-to-tail cyclic backbone and cystine knot core. These structural features underpin the native bioactivities of cyclotides, as well beneficial properties pharmaceutical leads, including high proteolytic stability cell permeability. However, inherent complexity presents a challenge for cyclotide engineering, particularly accessing libraries sufficient chemical diversity to design potent selective variants. Here,...
Abstract Gastric cancer (GC) is the 5 th most prevalent and 4 primary cancer-associated mortality globally. As first identified m6A demethylase for removing RNA methylation modification, fat mass obesity-associated protein ( FTO ) plays instrumental roles in development. Therefore, we study biological functions oncogenic mechanisms of GC tumorigenesis progression. In our study, expression obviously upregulated tissues cells. The upregulation associated with advanced nerve invasion, tumor...
<title>Abstract</title> <bold>Background: </bold>The direct observation of procedural skills for knee joint mobilization (DOPS<sub>knee</sub>) tool requires validation to ensure its reliability and validity providing immediate feedback assessing applicability in off-site settings. We aimed describe the implementation clinimetric properties DOPS<sub>knee</sub> both on-site environments, as well evaluate preclinical competencies physical therapy (PT) students. <bold>Methods:</bold> Following...
<title>Abstract</title> <bold>Background: </bold>The direct observation of procedural skills for knee joint mobilization (DOPS<sub>knee</sub>) tool requires validation to ensure its reliability and validity providing immediate feedback assessing applicability in off-site settings. We aimed describe the implementation clinimetric properties DOPS<sub>knee</sub> both on-site environments, as well evaluate preclinical competencies physical therapy (PT) students. <bold>Methods:</bold> Following...
Simultaneously improving strength and ductility is a challenge for Mg alloys. Herein, we report strong ductile Mg90Y4Zn2Ni4 (at. %) extrusion alloy with yield of 426 MPa, ultimate tensile 451 MPa elongation 25%. Experiment phase field model show that 14H-LPSO phases refine from blocks to lamellas through cracking, dissolving kinking during deformation. Moreover, excellent strength-ductility balance attributed fully fine recrystallized grains, dispersed Mg(Ni, Zn)4Y particles lamellas,...
In Brief Purpose: We sought to examine whether children with cerebral palsy (CP) demonstrate anticipatory postural adjustments (APAs) similar those observed in typical development (TD). Methods: A sample of convenience 14 children, seven CP and TD, participated this study. The center pressure (COP) was calculated from ground reaction force data collected the AMTI (OR-6) platform as child reached forward while standing. Results: Posterior COP shift frequently both groups before arm movement....
Parental concern is a useful screening approach for early detection of children with developmental delay. We investigated the relationships among parental concerns, functional impairment, and final diagnosis (n = 273) delays. Of these, motor, language, global delay were most common. especially in language motor development, good predictors or delay, provided reliable information delays these domains. Parents less likely to identify cognitive problems, associated behavioral problems....
[Purpose] Muscle co-contraction is important in stabilizing the spine. The aim of this study was to compare cervical muscle adults with and without chronic neck pain during voluntary movements. [Subjects Methods] Surface electromyography three paired muscles measured fifteen young healthy subjects patients pain. performed movements sagittal coronal plane at slow speed. ratio defined as normalized integration antagonistic activities divided by that total activities. [Results] results showed...
Objective: To investigate the effect of dietary fiber intake during pregnancy on prevention gestational diabetes mellitus (GDM) in women who are overweight/obese prior to pregnancy. Methods: This randomized controlled trial was conducted Shanghai General Hospital from June 2021 March 2022. A total 98 reported BMI≥24 kg/m 2 were recruited before their 20th week, and randomly (simple random allocation) assigned supplement group (12 g power twice daily) control (standard prenatal care) 20 24 +6...
// Jingjing Yu 1 , Yuling Huang 2 Lijuan Liu 3 Jing Wang Jiye Yin 4 Lihua 5 Shaojun Chen 6 Jingao Li Hong Yuan Guoping Yang Wenyu 7 Hai 8 Qi Pei Chengxian Guo Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China Department Radiation Oncology, Jiangxi Province Tumor Nanchang, 330029, Pharmacy, Cancer Nanchang 410008, for Medical Experiments, Fourth Affiliated Guangxi Liuzhou, 545005, College College, Correspondence to: Guo,...
Formins are conserved eukaryotic proteins that direct the nucleation and elongation of unbranched actin filaments. The yeast formins, Bni1p Bnr1p, assemble cables from bud cortex neck, respectively, to guide overall cell polarity. Here we examine regions Bnr1p responsible for neck localization. We define two non-overlapping regions, Bnr1p-L1 (1-466) Bnr1p-L2 (466-733), can each localize independently endogenous Bnr1p. with septins at but show slightly differently spatial temporal...
To examine the relationships between gross motor functions and physical psychosocial components of health-related quality life children with cerebral palsy.Participants comprising 90 (53 boys, 37 girls; mean age +/- SD = 8.2 2.4 yrs) palsy were enrolled by a cross-sectional design. Gross function measure was used to quantify their functions. Their determined Child Health Questionnaire-Parent Form 50 (traditional Chinese version), completed caregivers.A significant moderate positive...