A5002527606- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Pregnancy and Medication Impact
- Neuroscience and Neuropharmacology Research
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- COVID-19 Clinical Research Studies
- Pregnancy and preeclampsia studies
- Hemoglobinopathies and Related Disorders
- COVID-19 and healthcare impacts
- Pharmacology and Obesity Treatment
- Neurological disorders and treatments
- Tuberous Sclerosis Complex Research
- Acute Ischemic Stroke Management
- Advanced NMR Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Breastfeeding Practices and Influences
- Innovative Educational Techniques
- Genomics and Rare Diseases
- Neuroscience and Neural Engineering
- Folate and B Vitamins Research
- Long-Term Effects of COVID-19
- Video Analysis and Summarization
- Fetal and Pediatric Neurological Disorders
- Cardiac electrophysiology and arrhythmias
West China Hospital of Sichuan University
2015-2025
Sichuan University
2015-2025
Shanghai Center for Brain Science and Brain-Inspired Technology
2023
Zero to Three
2019
The Royal Melbourne Hospital
2018
The University of Melbourne
2018
To compare the severity of psychological distress between patients with epilepsy and healthy controls during COVID-19 outbreak in southwest China, as well identify potential risk factors severe among epilepsy.This cross-sectional case-control study examined a consecutive sample older than 15 years treated at center West China Hospital February 1 29, 2020. As controls, sex- age-matched visitors inpatients (unrelated to patients) were also enrolled same period. Data on demographics attention...
Abstract Objective Data on seizure and pregnancy outcomes in Asian women with epilepsy are limited. We used a Chinese registry to assess the impact of seizures antiseizure medications (ASMs) pregnant their children. Methods This is an ongoing prospective multicenter study that has been running since 2012. Eligible participants were consecutively enrolled had multiple follow‐ups up one year after delivery. assessed ASM use frequency during establish potential effects mothers infants identify...
The use of multidisciplinary teams (MDTs) is a global trend in disease management, while China still at the exploratory stage MDTs. We aimed to summarize our experience and assess impact MDT managing patients with epilepsy optimizing their seizure outcomes.Our staffed skilled epileptologists, electroencephalography experts, neurosurgeons, child neurologists, radiologists, psychiatrists. discussion has been carried out once or twice week since 2013. reviewed consecutive discussed from March...
Frontal lobe epilepsy (FLE) is the second most common type of focal epilepsies. Our understanding this disease has been revolutionized over past decade, but variable treatment outcomes persist and underlying functional mechanisms responsible for have yet to be deciphered. This study was designed determine how intrinsic brain connectivity related response in patients with FLE. 50 FLE 28 healthy controls were enrolled underwent MRI at baseline. At end 12-month follow up period, all classified,...
Abstract The occurrence of seizures during pregnancy is really a challenging situation which risks the health both mothers and fetuses. However, new onset epilepsy unpredictable in pregnancy, its clinic feature barely known. This study aimed to explore clinical characteristics outcomes pregnancy. We screened consecutive women with reproductive history from June 2013 November 2018 3 hospitals West China. Detailed demographics, features, neurological status, related tests, managements, seizure...
The role of ethnicity on pregnancy outcomes women with epilepsy (WWE) has received little research attention but is important to guide management. aim this review identify and describe current knowledge for WWE giving birth. Literature searches were performed the following terms: ethnic/race combined epilepsy/seizure, antiepileptic drugs (AED), and/or pregnancy, them congenital malformation, birth outcome, or complication, English language restriction in PubMed, EMBASE, Web Science. Both...
Abstract Background Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is typically resistant to pharmacological interventions; however, achieving seizure freedom possible through surgery. Our objective was focus on the pregnancy and outcomes during of women TLE-HS, aim identify predictors control. Methods The West China Registry Pregnancy Women Epilepsy (WCPR_EPi) a monocentric prospective cohort study (WWE). We screened TLE-HS in this database. Their clinical profile, anti-seizure...
Rationale: Tuberous sclerosis complex (TSC) is an uncommon multiple systems disorder. The main characteristics of the disease in central nervous system include cortical or subcortical tubers, subependymal nodules, and giant cell astrocytoma. However, progressive cystic lesions cerebral hemispheres have rarely been reported previous studies TSC. Patient concerns: We present case a 35-year-old man with TSC who was admitted to our hospital for sudden attack serious headache, vomiting, left...
Abstract Background Seizure control during pregnancy and obstetric outcomes are of important concerns for women with epilepsy (WWE) their families. Advanced maternal age (≥35 years) shows a growing trend in the society changes lifestyle, which also occurs diseased populations. The advanced is an independent factor some unsatisfying outcomes. In this study we explored seizure complications associated WWE. Methods This was based on registry at West China Hospital. Patients who were aged 35 or...
Abstract Background The optimal management of epilepsy includes engaging patients through education on knowledge the disease, its treatment and diet control. Methods This was a cross-sectional survey-based cohort study, aimed to investigate awareness in Chinese understand their dietary habits. Participants were consecutively enrolled from epileptic treated single center October 1, 2019 February 29, 2020. A self-reported questionnaire (Cronbach’s α = 0.758) consisting 3 parts sent 407 with...
<b>Backgrounds:</b> Apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptor 2 (also called death 5, DR5) is found to be involved in the pathogenesis of ALI. However, their clinical roles ARDS remains unclear. <b>Methods:</b> This study was approved ethic committee. patients were enrolled following Berlin definition, control subjects who not diagnosed with any pulmonary disorders recruited. Then serum bronchoalveolar lavage fluid (BALF) levels...
Virtual slides were applied in experiment teaching of pathology on trial clinic medicine college Sichuan university.The resuhs from the Survey showed that students and teachers preferred virtual learning microscopic lesions.Virtual Slides can help us save time,promote quality observation,carry out discussion based manage documents.It be used network after marking lesions. Key words: Virtual slides; Pathology; Experiment