A5100356617- Functional Brain Connectivity Studies
- COVID-19 and Mental Health
- Sleep and related disorders
- Sleep and Wakefulness Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Mental Health Research Topics
- Mental Health Treatment and Access
- Bipolar Disorder and Treatment
- Acute Ischemic Stroke Management
- Treatment of Major Depression
- Advanced Neuroimaging Techniques and Applications
- Obstructive Sleep Apnea Research
- Plant-based Medicinal Research
- Advanced MRI Techniques and Applications
- Color perception and design
- Circadian rhythm and melatonin
- Transcranial Magnetic Stimulation Studies
- Neuroscience of respiration and sleep
- Parkinson's Disease Mechanisms and Treatments
- EEG and Brain-Computer Interfaces
- Alzheimer's disease research and treatments
- Neural dynamics and brain function
- Health disparities and outcomes
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
Soochow University
2020-2024
Suzhou Guangji Hospital
2016-2024
Changzhou Vocational Institute of Textile and Garment
2024
Zhengzhou University
2012-2024
China Medical University
2014-2024
Fifth Affiliated Hospital of Zhengzhou University
2021-2024
University of British Columbia
2024
Guangzhou University of Chinese Medicine
2024
As the epidemic outbreak of 2019 coronavirus disease (COVID-19), general population may experience psychological distress. Evidence has suggested that negative coping styles be related to subsequent mental illness. Therefore, we investigate population's distress and in early stages COVID-19 outbreak. A cross-sectional battery surveys was conducted from February 1–4, 2020. The Kessler 6 scale, simplified style questionnaire a information were administered on-line convenience sample 1599...
Abstract Background The purpose of this study was to investigate the psychological status general population in mainland China during outbreak coronavirus disease 2019 (COVID-19), and explore factors influencing distress, order provide basis for further intervention programs. Methods We administered three questionnaires on-line a convenience sample from different regions February 1 4, 2020. used Mandarin versions six-item Kessler distress scale (K6), Simplified Coping Style Questionnaire...
To compare the severity of psychological distress between patients with epilepsy and healthy controls during COVID-19 outbreak in southwest China, as well identify potential risk factors severe among epilepsy.This cross-sectional case-control study examined a consecutive sample older than 15 years treated at center West China Hospital February 1 29, 2020. As controls, sex- age-matched visitors inpatients (unrelated to patients) were also enrolled same period. Data on demographics attention...
Abstract Background As the epidemic outbreak of 2019 coronavirus disease (COVID-19), general population may experience psychological distress. Evidence has suggested that negative coping styles be related to subsequent mental illness. Therefore, we investigate population’s distress and in early stages COVID-19 outbreak. Methods A cross-sectional battery surveys was conducted from February 1-4, 2020. The Kessler 6 scale, simplified style questionnaire a information were administered on-line...
Background: The COVID-19 pandemic has had impact that may contribute to a rise in mental health problems. present study was aimed better understand psychological status among medical staff and students during the early epidemic explore influence factors of distress. Methods: A cross-sectional survey conducted online from February 2–14, 2020. We collected general information related outbreak. Respondents were assessed using Kessler-6 Psychological Distress Scale (K6), Social Support Rating...
Backgrounds Recent research suggests that uric acid, as a metabolite with antioxidant properties, may affect muscle function and health. However, the association between serum acid (SUA) low mass remains relatively obscure. This study focuses on SUA in middle-aged elderly population United States. Methods Utilizing data from National Health Nutrition Examination Survey (NHANES), total of 12,106 patients aged ≥45 years, possessing complete analytical data, were incorporated. Low our is...
Objectives Post-traumatic stress disorder (PTSD) is a common psychological maladjustment to undergoing traumatic event. Our aim was measure the prevalence of PTSD among Chinese healthcare workers exposed physical violence‚ and explore associations their demographic characteristics, social support, personality traits‚ coping styles with symptoms. Methods A cross-sectional study conducted using Workplace Violence Scale, Posttraumatic Stress Disorder Checklist-Civilian Version (PCL-C), Social...
Background and Purpose— Mechanisms, acute management, outcomes for patients who experience intracerebral hemorrhage may differ from with ischemic stroke. Studies of very early rehabilitation have been mainly undertaken in stroke, it is unknown if benefits apply to those hemorrhage. We hypothesized that rehabilitation, within 48 hours would improve survival functional Methods— This was a multicenter, randomized controlled study, blinded assessment outcome at 3 6 months. Eligible were receive...
<h3>Background:</h3> It is unknown whether impaired coupling among 3 core large-scale brain networks (salience [SN], default mode [DMN] and executive control [ECN]) associated with relapse behaviour in treated heroin-dependent patients. <h3>Methods:</h3> We conducted a prospective resting-state functional MRI study comparing the connectivity strength healthy controls men who had either relapsed or were early remission. Men considered to be remission based on urine drug screens during 3-month...
Abstract Minimally invasive, high-bandwidth brain-computer-interface (BCI) devices can revolutionize human applications. With orders-of-magnitude improvements in volumetric efficiency over other BCI technologies, we developed a 50-μm-thick, mechanically flexible micro-electrocorticography (μECoG) BCI, integrating 256×256 electrodes, signal processing, data telemetry, and wireless powering on single complementary metal-oxide-semiconductor (CMOS) substrate containing 65,536 recording 16,384...
Background With the popularity of smart phones and development information technology, more patients are adopting diabetes APPs for self-management. However, at present, there few research reports on effect those coming from China. Objective The purpose this study was to evaluate effectiveness applicability an APP blood glucose control that is widely popular among Chinese with type 2 mellitus (T2DM). Methods This a 2-center, factorial design, equal proportional distribution, superiority...
Background/Aims: TREM2 plays a crucial role in modulating microglial function through interaction with DAP12, the adapter for TREM2. Emerging evidence has demonstrated that could suppress neuroinflammatory responses by repression of microglia-mediated cytokine production. This study investigated potential surgery-induced cognitive deficits and wild-type (WT) APPswe/PS1dE9 mice. Methods: Adult transgenic male mice (a classic model Alzheimer’s disease, 3 months old) their age-matched WT...
Objective While individuals with insomnia consistently complain of cognitive impairment, previous studies on the effect objective measures function have obtained ambiguous results. The relationship between daytime sleepiness and manifestations in patients is not clear. Methods Thirty-six primary (PIPs) 26 good sleep controls (GSCs) age gender matched manner were included study. Participants underwent an overnight polysomnography followed by a multiple latency test (MSLT) examination...
Craving is associated with a high probability of relapse. However, the relationship between functional connectivity in default mode network (DMN) during resting state and basal craving heroin-dependent individuals remains unknown.Data used present study were collected August 10, 2009, June 28, 2011. Twenty-four male based on DSM-IV criteria 20 healthy control subjects participated resting-state magnetic resonance imaging. The heroin group was evaluated. DMN networks identified by independent...
Abstract Depression may be associated with reduced monoamine neurotransmission, particularly serotonin and norepinephrine (NE). Reuptake of NE by the transporter (NET) is primary mechanism which many antidepressants are high-affinity substrates for NET. This study aimed to examine effect lentivirus-mediated shRNA targeting NET in locus coeruleus (LC) on depression-like behaviors rats. We randomly assigned 60 male Wistar rats 6 experimental groups: (1) Control group: without chronic...
This study aimed to investigate the mental state of medical staff and students in early stages SARS-CoV-2 outbreak, as well analyze risk factors serious illness (SMI), so provide a scientific basis for further psychological intervention management. A cross-sectional survey was conducted from February 2–7, 2020. The Kessler 6 Psychological Distress Scale general information questionnaire were administered on-line convenience sample 548 China. Multivariate binary logistic regression analysis...