Lian Yuan

ORCID: 0000-0001-9543-9072
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About
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Research Areas
  • Mitochondrial Function and Pathology
  • Electrochemical Analysis and Applications
  • Trace Elements in Health
  • ATP Synthase and ATPases Research
  • Functional Brain Connectivity Studies
  • Schizophrenia research and treatment
  • Advanced MRI Techniques and Applications
  • Alzheimer's disease research and treatments
  • Protein Interaction Studies and Fluorescence Analysis
  • Surfactants and Colloidal Systems
  • Tryptophan and brain disorders
  • Nuclear Receptors and Signaling
  • Maritime Ports and Logistics
  • Fetal and Pediatric Neurological Disorders
  • Gas Sensing Nanomaterials and Sensors
  • Fuel Cells and Related Materials
  • Advanced Photocatalysis Techniques
  • Traditional Chinese Medicine Studies
  • Heavy Metal Exposure and Toxicity
  • Advanced Cellulose Research Studies
  • Botanical Research and Chemistry
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Electron Spin Resonance Studies
  • Lignin and Wood Chemistry
  • Treatment of Major Depression

Fujian Agriculture and Forestry University
2023

Suzhou Guangji Hospital
2019-2022

Soochow University
2019-2022

Guang’anmen Hospital
2022

Tokyo Institute of Technology
2021

East Tennessee State University
2019

Wuhan University
2013-2017

In-Q-Tel
2017

State Key Laboratory of Virology
2013-2017

Capital Medical University
2014

Abstract Three different sizes (15.9 ± 2.1 nm, 26.4 3.2 nm and 39.8 4.0 respectively) of citrate‐coated silver nanoparticles (SNPs) have been synthesized characterized. The interactions the SNPs with human serum albumin (HSA) at physiological pH systematically studied by UV‐vis absorption spectroscopy, fluorescence synchronous three‐dimensional spectroscopy circular dichroism (CD) spectroscopy. results indicate that can bind to HSA high affinity quench intrinsic HSA. binding constants...

10.1002/bio.2748 article EN Luminescence 2014-08-08

Abstract Depression may be associated with reduced monoamine neurotransmission, particularly serotonin and norepinephrine (NE). Reuptake of NE by the transporter (NET) is primary mechanism which many antidepressants are high-affinity substrates for NET. This study aimed to examine effect lentivirus-mediated shRNA targeting NET in locus coeruleus (LC) on depression-like behaviors rats. We randomly assigned 60 male Wistar rats 6 experimental groups: (1) Control group: without chronic...

10.1038/s41398-020-0808-8 article EN cc-by Translational Psychiatry 2020-05-04

The high mechanical strength, large specific surface area, favorable biocompatibility, and degradability of nanocellulose (CNC) enable it to be a potential alternative petroleum-based materials. However, the traditional preparation CNCs requires amount strong acid, which poses serious challenge equipment maintenance, waste liquid recycling, economics. In this study, solid easily recoverable zirconium phosphate (ZrP) was used assist in phosphoric acid co-catalyzed hydrolysis lignocellulose...

10.3390/polym15020447 article EN Polymers 2023-01-14

As a novel delocalized lipophilic cation, F16 selectively accumulates in mitochondria of carcinoma cells and shows broad spectrum antiproliferative action towards cancer cell lines. In order to reveal the mode molecular mechanism inducing cytotoxicity, we investigated effects on isolated relative its precursor compound (E)-3-(2-(pyridine-4yl)vinyl)-1 H-indole (PVI), which has similar structure without positive charge. It was found that PVI did not accumulate mitochondria, exhibited lower...

10.1093/toxsci/kfx218 article EN Toxicological Sciences 2017-10-20

Multiple methods are employed to reveal the effects and nonspecific mechanism of silver(<sc>i</sc>) ions on isolated mitochondria.

10.1039/c7tx00079k article EN Toxicology Research 2017-01-01

Organic arsenical<bold>MOPIMP</bold>induced mitochondrial membrane permeability transition pore opening, respiration suppression and metabolic thermogenesis dysfunction in isolated mitochondria.

10.1039/c7tx00234c article EN Toxicology Research 2017-12-19

Abstract Background Cognitive impairment is core feature of schizophrenia. The impact antipsychotics on cognition remains controversial. This study aimed to examine the effects long‐term use different types cognitive in schizophrenia patients. Methods We used Repeatable Battery for Assessment Neuropsychological Status (RBANS) assess three groups patients (318 clozapine, 125 risperidone, and 166 typical antipsychotic drugs) 399 healthy controls, Positive Negative Syndrome Scale symptoms...

10.1002/hup.2754 article EN Human Psychopharmacology Clinical and Experimental 2020-09-17

Herein, chemically modified HSAs with different surface charges are used to study the process of protein fibrillation and inhibition mechanism quantum dots (QDs) in aqueous solutions<italic>in vitro</italic>.

10.1039/c6ra20303e article EN RSC Advances 2016-01-01

The origin of the S1 ← S0 transition (E1) and adiabatic ionization energy (IE) cis-p-methoxyphenol-d1-OD are determined to be 33 660 62 302 cm-1, whereas those cis-p-methoxyphenol-d1-OCH2D 669 323 respectively. Similarly, E1 IE trans-p-methoxyphenol-d1-OD 563 191 cm-1 trans-p-methoxyphenol-d1-OCH2D 575 216 Comparing these data with p-methoxyphenol suggests that H/D exchange on OH substituent gives rise a red shift in both IE, OCH3 group yields blue shift. mass-analyzed threshold spectra...

10.1021/jp052850c article EN The Journal of Physical Chemistry A 2005-09-30

Owing to hardware advancements, a resurgence of interest has emerged in low field MRI systems recently. However, the intrinsic signal noise ratio (SNR) due magnetic strength hindered acquisition high-resolution images on systems. Here we propose non-local robust PCA-based method jointly denoise multi-contrast acquired 0.5 T system. In-vivo brain data are used test proposed method. The results show that outperforms BM3D and BM4D denoising methods.

10.58530/2022/4715 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2023-08-03

Objective To investigate the clinical significance between congestive heart failure (CHF) and serum thyroxine. Methods 50 patients with CHF (7 cases of grade Ⅱ function,grade Ⅲ 19 cases,grade Ⅳ 24)and 30 normal persons wre selected. The triiodothyronine( T3 ), four-triiodothyronine( T4 free triiodothyronine (FT3), (FT4), thyroid stimulating hormone TSH were determined by radioimmunoassay. Results T3, FT3 contens ( 1.95 ± 0.55) nmol/L, (2.20 0.39 ) pmol/L in group lower than control (2.4...

10.3760/cma.j.issn.1008-6706.2010.19.015 article EN Zhongguo jiceng yiyao 2010-10-01

Abstract Depression and obesity are both risk factors for suicide attempts; however, the pattern of attempts in individuals with major depressive disorder (MDD) who overweight or obese remains uncertain. The purpose this study was to examine prevalence variables first-episode drug-naïve (FEND) MDD patients obesity. This included a total 1026 FEDN were obese. Their demographic data metabolic parameters collected. To patients' symptoms, researchers employed Hamilton Scale (HAMD), Anxiety...

10.21203/rs.3.rs-1484694/v1 preprint EN cc-by Research Square (Research Square) 2022-04-01

Rationale: Pseudoaneurysm (PSA) is a common complication related to vascular intervention, and surgical therapy the primary method. However, giant brachial artery PSA over 2 weeks rarely observed. Due adhesion of surrounding tissue, thrombus organization, extensive injury, high expense transluminal stent-graft placement, single ultrasound-guided local high-dose thrombin injection can be option. Such cases are reported. Patient concerns: A 71-year-old man with history left elbow fossa...

10.1097/md.0000000000030103 article EN cc-by-nc Medicine 2022-08-19
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