Organic fluorescent nanoparticles, excitation-dependent photoluminescence, hydrogen-bonded clusters and lysobisphosphatidic acid are four interesting individual topics in materials biological sciences. They have attracted much attention not only because of their unique properties important applications, but also the nature intriguing phenomena remained unclear. Here we report a new type organic nanoparticles with intense blue visible fluorescence range 410–620 nm. The composed ten...

Robot-assisted therapy (RT) is a widely used intervention approach to enhance motor recovery in patients after stroke, but its effects on functional improvement remained uncertain. Neuromuscular electrical stimulation (NMES) one potential adjuvant RT that could directly activate the stimulated muscles and improve use of paretic hand. This was randomized, double-blind, sham-controlled study. Thirty-nine individuals with chronic stroke were randomly assigned combined NMES (RT + ES) or sham...

Background. Few studies have addressed early out-of-bed mobilization specifically in acute intracerebral hemorrhage (ICH) patients. Patient benefit such cases is unclear, with intervention timing and duration identical to those standard care. Objective. We investigated the efficacy of an (EM) protocol, administered within 24 72 hours stroke onset, for functional independence mild-moderate ICH Methods. Sixty patients admitted a center were randomly assigned or rehabilitation (SER). The EM...

This study was conducted to evaluate the risks of adverse birth outcomes including low birthweight, preterm and small-for-gestational age among teen mothers.Data were collected from Taiwan Birth Registry between 1985 1997. Among a total 1,185,597 live births born mothers aged 24 years or less, 151,259 (12.8%) 19 less. Crude odds ratios (ORs), adjusted ORs (AORs), their 95% confidence intervals test for linear trend maternal age-specific AOR estimated using logistic regression analysis.After...

Summary Chronic kidney disease (CKD) is a worldwide health issue with heavy economic burden. hepatitis C virus (HCV) infection common cause of CKD, which can significantly impact the progression and mortality among patients CKD. The prevalence both illnesses high in Taiwan. A multicentre population‐based cross‐sectional study including 24 642 subjects was conducted to explore association HCV severity measurements metabolic parameters, eGFR CKD stages were compared between seropositivity...

The purpose of this study was to examine the effects downhill walking training on gait and thoracic kyphosis in patients with Parkinson's disease.Thirty-three disease were randomized into an experimental group (n = 16) or a control 17). Subjects underwent 4-wks training, whereas subjects received conventional therapy for 4 wks. Gait parameters, kyphosis, muscle strength knee measured at pretraining, posttraining, 1-mo follow-up.There significant interaction between time evaluation parameters...

Proteus mirabilis is a urinary tract pathogen and well known for its ability to move over agar surfaces by flagellum-dependent swarming motility. When P. encounters highly viscous environment, e.g., an surface, it differentiates from short rods with few flagella elongated, flagellated cells that lack septa contain multiple nucleoids. The bacteria detect surface monitoring the rotation of their flagellar motors. This process involves enigmatic protein called FliL, first gene in operon...

Nonpharmacologic interventions, such as cognitive training or physical exercise, are effective in improving functions for older adults with mild impairment (MCI). Some researchers have proposed that combining exercise may augment the benefits of cognition. However, strong evidence is lacking regarding whether a combined therapy superior to single type MCI. Moreover, which combination approach – sequentially simultaneously more advantageous improvement not yet clear. This study designed...

It has been proposed that strengthening and skill training of gluteus maximus (GM) may be beneficial in treating various knee injuries. Given the redundancy hip musculature small representational area GM primary motor cortex (M1), learning to activate this muscle before prescribing strength exercises modifying movement strategy would appear important. This study aimed determine whether a short-term activation program targeting results neuroplastic changes M1. Using transcranial magnetic...

Mirror therapy (MT) combined with mesh glove (MG) afferent stimulation (MT + MG) has been suggested as an effective intervention for motor recovery in patients stroke. This study aimed to further determine the treatment effects of MT MG approach on muscular properties, sensorimotor functions, and daily function.This was a single-blind, randomized, placebo-controlled study. Forty-eight participants chronic stroke were recruited from medical centers randomly assigned MT, MG, sham sham) groups....

Study Design Controlled laboratory study. Background Joint mobilization and manipulation decrease pain improve patient function. Yet, the processes underlying these changes are not well understood. Measures of corticospinal excitability provide insight into potential mechanisms mediated by central nervous system. Objectives To investigate differential effects joint at talocrural on in individuals with resolved symptoms following ankle sprain. Methods Twenty-seven participants a history...

Degenerative cervical myelopathy (DCM) is a common aging condition caused by spinal cord compression. Individuals with DCM often presented residual balance and functional impairments postoperatively. Perturbation-based training (PBT) has been shown to have positive effects on populations neurological disorders but yet be investigated in DCM. The objective of this study was therefore evaluate the PBT performance postoperative individuals Fifteen (DCM group) 14 healthy adults (healthy control...

The priming effect of mirror visual feedback can be simply provided by inexpensive therapy (MT), which exhibits beneficial effects on sensorimotor recovery in stroke. present study was a single-blind pretest-posttest that examined whether the bilateral task practice would render better outcomes. Twenty-three patients with chronic stroke were randomized to receive hospital-based task-oriented MT or arm training (BAT) for 4 weeks at 90 minutes/day, 3 days/week and home 30-40 5 days/week. There...

Reliability study.To determine the feasibility and reliability of using transcranial magnetic stimulation (TMS) to assess corticomotor excitability (CE) gluteus maximus.Sport-specific skill training targeting greater utilization maximus has been proposed as a method reduce incidence noncontact knee injuries. The use TMS changes in CE may help training-induced central mechanisms associated with activation.Within- between-day was measured 10 healthy adults. by stimulating ìhotspotî at 120%...

Context-dependent learning is a phenomenon in which people demonstrate superior performance the context they originally learned skill but perform less well novel context. This study investigated context-dependent with Parkinson's disease (PD) and age-matched nondisabled adults. All participants practiced 3 finger sequences, each embedded within unique (colors locations on computer screen). One day after practice, were tested either under sequence-context associations remained same as during...

Abstract Objective Verbal instruction is one of the most commonly used methods that therapists use to correct walking pattern for people with Parkinson’s disease (PD). This study aimed compare long-term training effects two different verbal instructions either asked participants ‘take big steps’ or ‘strike ground heel’ on ability in individuals PD. Design Forty-five PD were randomized into big-step (BIG) heel strike (HS) group. The underwent 12 sessions treadmill and overground gait...