A5086579423- Stroke Rehabilitation and Recovery
- Cardiac Arrest and Resuscitation
- Muscle activation and electromyography studies
- Traumatic Brain Injury and Neurovascular Disturbances
- EEG and Brain-Computer Interfaces
- Transcranial Magnetic Stimulation Studies
- Prosthetics and Rehabilitation Robotics
- Anesthesia and Neurotoxicity Research
- Cardiac Ischemia and Reperfusion
- Cerebral Palsy and Movement Disorders
- Functional Brain Connectivity Studies
- Acute Ischemic Stroke Management
- Botulinum Toxin and Related Neurological Disorders
- Thermal Regulation in Medicine
- Musculoskeletal pain and rehabilitation
- Dementia and Cognitive Impairment Research
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Optical Imaging and Spectroscopy Techniques
- Mental Health Research Topics
- Neuroscience of respiration and sleep
- S100 Proteins and Annexins
- Ergonomics and Musculoskeletal Disorders
- Complementary and Alternative Medicine Studies
- Gaze Tracking and Assistive Technology
Tan Tock Seng Hospital
2024
Nanyang Technological University
2024
National Yang Ming Chiao Tung University
2023
Fujita Health University
2022
National University of Singapore
2017-2021
Duke-NUS Medical School
2020
National Taiwan University
2011-2019
Chia-Yi Christian Hospital
2018
National Taiwan University Hospital
2009-2015
Robot-assisted therapy (RT) is a widely used intervention approach to enhance motor recovery in patients after stroke, but its effects on functional improvement remained uncertain. Neuromuscular electrical stimulation (NMES) one potential adjuvant RT that could directly activate the stimulated muscles and improve use of paretic hand. This was randomized, double-blind, sham-controlled study. Thirty-nine individuals with chronic stroke were randomly assigned combined NMES (RT + ES) or sham...
Abstract Stroke leads to both regional brain functional disruptions and network reorganization. However, how networks reconfigure as task demand increases in stroke patients whether such reorganization at baseline would facilitate post-stroke motor recovery are largely unknown. To address this gap, connectivity (FC) were examined rest tasks eighteen chronic subcortical eleven age-matched healthy controls. underwent a 2-week intervention using imagery-assisted computer interface-based...
Mild-to-moderate therapeutic hypothermia after resuscitation from cardiac arrest is neuroprotective, but its effect on postresuscitation myocardial dysfunction not clear. We hypothesized that cardioprotective in postresuscitation. Male adult Wistar rats underwent asphyxia-induced and manual with epinephrine. Therapeutic induced immediately successful the return of spontaneous circulation (ROSC). One hour ROSC, achieved a target temperature 30 degrees C to 31 C, which was maintained for 1.5 h...
Brain-computer interface-assisted motor imagery (MI-BCI) or transcranial direct current stimulation (tDCS) has been proven effective in post-stroke function enhancement, yet whether the combination of MI-BCI and tDCS may further benefit rehabilitation functions remains unknown. This study investigated brain functional activity connectivity changes after a 2 week combined intervention 19 chronic subcortical stroke patients. Patients were randomized into with group only who underwent 10...
Abstract Background Effective stroke rehabilitation requires high-dose, repetitive-task training, especially during the early recovery phase. However, usability of upper-limb technology in acute and subacute survivors remains relatively unexplored. In this study, we introduce to MyoGuide, a mobile training platform that employs surface electromyography (sEMG)-guided neurofeedback specifically targets wrist extension. Notably, study emphasizes evaluating platform’s within clinical contexts....
We evaluated the feasibility, safety, and efficacy of a 2D-planar robot for minimally supervised home-based upper-limb therapy post-stroke hemiparesis. The H-Man, end effector robot, combined with web-based software application remote tele-monitoring were at homes participants. Inclusion criteria were: strokes > 28 days, Fugl-Meyer Motor Assessment (FMA) 10-60/66, presence carer absence medical contraindications. Participants performed self-directed, robotics-assisted (RAT) home 30...
To investigate the effect of erythropoietin for management postresuscitation myocardial dysfunction following asphyxia-induced cardiac arrest. Male adult Wistar rats were used prospective controlled animal study. Asphyxia-induced arrest was performed by turning-off ventilator and clamping endotracheal tube. Cardiopulmonary resuscitation with an intravenous injection 0.01 mg/kg epinephrine mechanical ventilation started after 6.5 minutes asphyxia. The resuscitated animals received either...
Abstract Over one third of stroke patients have long-term cognitive impairment. The likelihood dysfunction is poorly predicted by the location or size infarct. macroscale damage caused ischaemic relatively localised, but effects occur across brain. Structural covariance networks represent voxelwise correlations in cortical morphometry. Atrophy and topographical changes within such distributed brain structural may contribute to decline after stroke, this has not been thoroughly investigated....
Bihemispheric tDCS combined with a novel MCI training for motor control of wrist extensor can improve upper limb function especially training-specific effect on the movement in patients chronic stroke. The regimen be personalized adjustments made daily to accommodate functional change throughout intervention. This demonstrates that bihemispheric could complement conventional poststroke neurorehabilitation.
Conjugated polymers (CPs) have been actively utilized as photocatalysts for hydrogen evolution due to their easy synthetic tunability endow specific functionalities, including visible-light absorption, higher-lying LUMO energy proton reduction, and sufficient photochemical stability. Enhancing interfacial surface compatibility of hydrophobic CPs with hydrophilic water is the central focus improve rate (HER). Although a number successful approaches developed in recent years, tedious chemical...
This paper presents a novel omnidirectional platform for gait rehabilitation of people with hemiparesis after stroke. The mobile platform, henceforth the "walker", allows unobstructed pelvic motion during walking, helps user maintain balance and prevents falls. system aids mobility actively by combining three types therapeutic intervention: forward propulsion pelvis, controlled body weight support, functional electrical stimulation (FES) compensation deficits in angular joints. FES is using...
Abstract One third of ischemic stroke patients develop cognitive impairment. It is not known whether topographical secondary neurodegeneration within distributed brain structural covariance networks (SCNs) underlies this decline. We examined longitudinal changes in SCNs and their relationship to domain-specific decline 73 patients. Patients were scanned with magnetic resonance imaging (MRI) assessed on five domains at subacute (3-months) chronic (1-year) timepoints. Individual-level SCN...
<title>Abstract</title> <bold>Aims:</bold> We evaluated the feasibility, safety and efficacy of a 2D-planar robot for minimally-supervised home-based upper-limb therapy post-stroke hemiparesis. <bold>Materials Methods:</bold> The H-Man, end effector robot, combined with web-based software application remote tele-monitoring were at homes participants. Inclusion criteria were: strokes > 28 days, Fugl-Meyer Motor Assessment (FMA) >10-60/66, presence carer absence medical...
Compensatory movements are commonly observed post-stroke and can negatively affect long-term motor recovery. In this context, a system that monitors movement quality provides feedback would be beneficial. study, we aimed to detect compensatory during seated reaching using conventional tablet camera an open-source markerless body pose tracking algorithm called MediaPipe [1]. We annotated of stroke patients per frame based on the comparison between paretic non-paretic arms. trained binary...
ABSTRACT Transcranial direct current stimulation (tDCS) may facilitate neuroplasticity but with a limited effect when administered while stroke patients are at rest. Muscle-computer interface (MCI) training is promising approach for even if they cannot produce overt movements. However, using tDCS to enhance MCI has not been investigated. We combined bihemispheric of the paretic wrist and examined effectiveness this intervention in chronic patients. A crossover, double-blind, randomized trial...
In this paper, a novel walker robot is proposed for post-stroke gait rehabilitation. It consists of an omni-directional mobile platform which provides high mobility in horizontal motion, linear motor that moves vertical direction to support the body weight patient and 6-axis force/torque sensor measure interaction between patient. The improves pelvis so it can provide more natural patterns This paper analytically derives kinematic dynamic models robot. Simulation results are given validate models.
We present a novel control method for an omnidirectional robotic platform gait training. This mobile or "walker" provides trunk support and allows unrestricted motion of the pelvis simultaneously. In addition to helping user maintain balance preventing falls, walker combines two types therapeutic intervention: forward propulsion partial body weight (BWS). The core walker's is admittance controller that maximizes platform's horizontal mobility by optimizing virtual mass model. Said represents...