Tzung‐Dau Wang
A5078892748- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Sodium Intake and Health
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sexual function and dysfunction studies
- Pharmaceutical industry and healthcare
- Cardiac Ischemia and Reperfusion
- Hormonal Regulation and Hypertension
- Hemodynamic Monitoring and Therapy
- Genetic Associations and Epidemiology
- Lipoproteins and Cardiovascular Health
- Hormonal and reproductive studies
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Non-Invasive Vital Sign Monitoring
- Cardiac electrophysiology and arrhythmias
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
National Taiwan University Hospital
2016-2025
National Taiwan University
2015-2024
Min Sheng General Hospital
2024
Cambridge University Hospitals NHS Foundation Trust
2024
Mackay Memorial Hospital
2010-2023
Far Eastern Memorial Hospital
2023
Sanofi (France)
2023
Eli Lilly (United States)
2023
Boehringer Ingelheim (United States)
2023
Daiichi Sankyo (Germany)
2023
The appropriate target for systolic blood pressure to reduce cardiovascular risk in older patients with hypertension remains unclear.
BackgroundIncreased blood pressure is the biggest contributor to global burden of disease and mortality. Data suggest that less than half population with hypertension aware it. May Measurement Month was initiated raise awareness importance as a pragmatic interim solution shortfall in screening programmes.MethodsThis cross-sectional survey included volunteer adults (≥18 years) who ideally had not their pressures measured past year. Each participant three times received questionnaire about...
Hypertension is the most important modifiable cause of cardiovascular (CV) disease and all-cause mortality worldwide. Despite positive correlations between blood pressure (BP) levels later CV events since BP as low 100/60 mmHg have been reported in numerous epidemiological studies, diagnostic criteria hypertension thresholds targets antihypertensive therapy largely remained at level 140/90 past 30 years. The publication both SPRINT STEP trials (comprising > 8,500 Caucasian/African Chinese...
It has been almost 5 years since the publication of 2010 hypertension guidelines Taiwan Society Cardiology (TSOC). There is new evidence regarding management hypertension, including randomized controlled trials, non-randomized post-hoc analyses, subgroup retrospective studies, cohort and registries. More recently, European Hypertension (ESH) (ESC) published joint in 2013. The panel members who were appointed to Eighth Joint National Committee (JNC) also 2014 JNC report. Blood pressure (BP)...
Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an RNA-binding expressed in embryonic tissues and multiple cancers. To investigate the role of IMP3 hepatocellular carcinoma (HCC), its expression surgically resected unifocal tumors 377 HCC patients (296 men 81 women) with ages ranging from 7 to 88 years (mean, 55.49 years) was analyzed by immunohistochemistry. 255 (67.6%) primary HCCs. predominantly tumor border invasive front, it more abundant satellite nodules thrombi than...
The effect of Ca2+ antagonist drugs on uptake and Na+-induced release by isolated rabbit heart mitochondria has been studied using arsenazo III dansylaziridine-labeled troponin C as indicators. Mitochondria accumulated 20 nmol Ca2+/mg protein a respiration-dependent process. A23187, carbonyl cyanide p-trifluoromethoxyphenylhydrazone, or Na+ induced from Ca2+-loaded ruthenium red (RR)-treated mitochondria. had no the process either A23187 p-trifluoromethoxyphenylhydrazone but they were...
Genome-wide association studies (GWAS) have identified ~100 loci associated with blood lipid levels, but much of the trait heritability remains unexplained, and at most identities trait-influencing variants remain unknown. We conducted a trans-ethnic fine-mapping study 18, 22, 18 GWAS on Metabochip for their triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density (LDL-C), respectively, in individuals African American (n = 6,832), East Asian 9,449), European 10,829)...
Salt-sensitive hypertension (SSH) is characterized by impaired sodium excretion and subnormal vasodilatory response to salt loading. Sacubitril/valsartan (LCZ696) was hypothesized increase natriuresis diuresis result in superior blood pressure control compared with valsartan Asian patients SSH. In this randomized, double-blind, crossover study, 72 SSH received sacubitril/valsartan 400 mg 320 once daily for 4 weeks each. diagnosed if the mean arterial increased ≥10% when switched from low (50...
Even though the increasing clinical recognition of primary aldosteronism (PA) as a public health issue, its heightened risk profiles and availability targeted surgical/medical treatment being more understood, consensus in diagnosis management based on medical evidence, while recognizing constraints our real-world practice Taiwan, has not been reached.The Taiwan Society Aldosteronism (TSA) Task Force acknowledges above-mentioned issues reached this PA at inaugural meeting, order to provide...
Cardiovascular disease (CVD) is becoming the most important burden to health care systems in part of world, especially Asia. Aiming at identifying high risk individuals and tailoring preventive treatment, many cardiovascular assessment tools have been established them were developed Western countries. However, these cannot be used interchangeably without recalibration because different factor profiles (ie, greater absolute hypertension lower level total-cholesterol Asians higher prevalence...
Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot. Its distribution asymmetrical and primarily concentrated in the grooves. To date, it remains unclear which measurement of EAT best reflects its metabolic risk.We aimed to examine correlations between various multidetector computed tomographic measurements EAT, syndrome components, plasma levels high-sensitivity C-reactive protein adipokines.This study included 148 consecutive patients undergoing tomography prior...