A5068644329- Neurobiology and Insect Physiology Research
- Silk-based biomaterials and applications
- Insect and Arachnid Ecology and Behavior
- Insect Resistance and Genetics
- Insect Utilization and Effects
- Silkworms and Sericulture Research
- Genetics, Aging, and Longevity in Model Organisms
- Protein Tyrosine Phosphatases
- Viral Infectious Diseases and Gene Expression in Insects
- Insect symbiosis and bacterial influences
- Microtubule and mitosis dynamics
- CRISPR and Genetic Engineering
- Coleoptera Taxonomy and Distribution
- RNA Research and Splicing
- Beetle Biology and Toxicology Studies
- Heat shock proteins research
- Galectins and Cancer Biology
- Natural product bioactivities and synthesis
- Invertebrate Immune Response Mechanisms
- Plant Reproductive Biology
- Antimicrobial Peptides and Activities
- Insect and Pesticide Research
- RNA modifications and cancer
- Histone Deacetylase Inhibitors Research
- Neuropeptides and Animal Physiology
Nihon University
2012-2025
National Agriculture and Food Research Organization
2019
Institute of Agrobiological Sciences
2012-2019
Tokyo Metropolitan University
1997-2009
University of Georgia
2007-2008
The Krüppel homolog 1 gene ( Kr-h1 ) has been proposed to play a key role in the repression of insect metamorphosis. is assumed be induced by juvenile hormone (JH) via JH receptor, methoprene-tolerant (Met), but mechanism induction unclear. To elucidate molecular induction, we first cloned cDNAs encoding BmKr-h1 and Met BmMet1 BmMet2 homologs from Bombyx mori . In B. cell line, was rapidly subnanomolar levels natural JHs. Reporter assays identified response element k JHRE), comprising 141...
Abstract Background The most abundant family of insect cuticular proteins, the CPR family, is recognized by R&R Consensus, a domain about 64 amino acids that binds to chitin and present throughout arthropods. Several species have now been shown more than 100 genes, inviting speculation as functional importance this large number diversity. Results We identified 156 genes in Anopheles gambiae code for putative proteins over 1% total predicted species. Annotation was verified using several...
The mandibles of coleopteran insects are typical examples external morphological asymmetry in animals. developmental molecular mechanisms underlying the remain to be elucidated compared those internal asymmetric organ. In tenebrionid beetle, Zophobas atratus , inner teeth adult asymmetric, while pupal nearly symmetric. morphogenesis is assumed caused by left-right regulatory differences formation, but even involved per se remains unknown. this study, we investigated morphogenetic process...
Histone deacetylases, such as silent information regulator 2 (Sir2) and Rpd3 are involved in chromatin silencing implicated lifespan determination several organisms. The yeast Dot1 gene encoding a histone methyltransferase affects localization of proteins including Sir2, plays an essential role the repair damaged DNA. However, it is not known whether alteration activity influences or stress resistance, which often associated with extended lifespan. Here we investigated Drosophilagrappa (gpp)...
To analyze the role of protein kinase CK2 (CK2) during early embryogenesis in non-diapause and diapause silkworm, distribution localization Bombyx mori (BmCK2) were investigated by an immunohistochemical technique using antibodies against α- β-subunits BmCK2. Both localized blastoderm cells eggs until 24 h after oviposition. More than oviposition, however, BmCK2 was different eggs. In eggs, mainly yolk cells. contrast, observed germ-band Furthermore, we confirmed that RNA helicase-like...
The fruit fly, Drosophila melanogaster, is an excellent model system for the study of complex biological processes including aging. Through genetic manipulation antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, roles these enzymes in oxidative stress resistance life span determination were established. Transgenic flies overexpressing enzyme peptide methionine sulfoxide reductase A (MSRA) have been shown to live longer are more resistant paraquat-induced stress. It has...
The amino acid sequence of the motor domain AnKinA, kinesin-1 from Aspergillus nidulans, growing optimally at 37°C, was compared with that SbKin1, snow mold Sclerotinia borealis. For cold-adaptation, some enzymes are thought to exhibit augmented protein structure flexibility, acquired most effectively by substituting a glycine residue for another residue. By comparison described above, two residues proximal tightly bound ADP were identified in SbKin1 domain, which corresponding AnKinA...
Resilin is an elastic protein that vital to insects’ vigorous movement. Canonical resilin proteins possess the R&R Consensus, a chitin-binding domain conserved in family of cuticular proteins, and highly repetitive sequences conferring properties. In malaria vector mosquito, Anopheles gambiae, however, has been found Consensus resembling but lacks (here, we call it resilin-related or resilin-r). The relationship between resilin-r was unclear. It also unknown whether mosquitoes. this...
Protein tyrosine phosphatase, mitochondrial 1 (PTPMT1) is a phosphatase that highly conserved in animals. Functional analyses using knockout animals have revealed variety of physiological roles PTPMT1 vertebrates and insects. However, because the high lethality these animals, later postembryonic development remain relatively obscure. In present study, RNA interference technique, we analyzed functions larval stages red flour beetle, Tribolium castaneum. was expressed both anterior posterior...