Yitong Chen

ORCID: 0000-0002-2577-2897
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About
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Research Areas
  • Energy Efficient Wireless Sensor Networks
  • Cancer-related gene regulation
  • Wireless Networks and Protocols
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Epigenetics and DNA Methylation
  • Gut microbiota and health
  • Computational Drug Discovery Methods
  • Blind Source Separation Techniques
  • Brain Tumor Detection and Classification
  • Indoor and Outdoor Localization Technologies
  • Sparse and Compressive Sensing Techniques
  • Distributed Sensor Networks and Detection Algorithms
  • Gene expression and cancer classification
  • Bioinformatics and Genomic Networks
  • Privacy-Preserving Technologies in Data
  • Genetic Associations and Epidemiology

Northwestern Polytechnical University
2024-2025

Guangxi Medical University
2023-2024

Henan University
2024

First Affiliated Hospital of GuangXi Medical University
2023-2024

Abstract As the most abundant messenger RNA (mRNA) modification, N6-methyladenosine (m6A) plays a crucial role in fate, impacting cellular and physiological processes various tumor types. However, our understanding of m6A methylome heterogeneity remains limited. Herein, we collected analyzed methylomes across nine human tissues from 97 sequencing (m6A-seq) (RNA-seq) samples. Our findings demonstrate that exhibits different compared to normal tissues, which contributes diverse clinical...

10.1093/gpbjnl/qzae052 article EN cc-by Genomics Proteomics & Bioinformatics 2024-07-05

10.1109/tsipn.2025.3543973 article EN IEEE Transactions on Signal and Information Processing over Networks 2025-01-01

This material introduces the D-Subspace algorithm derived on basis of centralized [1], which originally addresses parameter estimation problems under a subspace constraint.

10.48550/arxiv.2410.21320 preprint EN arXiv (Cornell University) 2024-10-26

Synthetic lethality (SL) is widely used to discover the anti-cancer drug targets. However, identification of SL interactions through wet experiments costly and inefficient. Hence, development efficient high-accuracy computational methods for prediction great significance. In this study, we propose MPASL, a multi-perspective learning knowledge graph attention network enhance synthetic prediction. MPASL utilizes hierarchy propagation explore multi-source neighbor nodes related genes. The...

10.3389/fphar.2024.1398231 article EN cc-by Frontiers in Pharmacology 2024-05-21

Federated learning has more flexible data ownership participants, therefore its (sample feature vector or label) is likely to be changed, and it vulnerable poisoning by malicious users, resulting in the final global model not getting expected effect. This paper focuses on this defense problem applies traditional centralized machine pruning optimization method each client of federated learning. Each needs execute before iteration. Pruning algorithm remove abnormal data. The experimental...

10.1117/12.3049006 article EN other-oa 2024-11-12

Abstract As the most abundant mRNA modification in mRNA, N 6 -methyladenosine (m A) plays a crucial role RNA fate, impacting cellular and physiological processes various tumor types. However, our understanding of function m A methylome heterogeneity remains limited. Herein, we collected analyzed methylomes across nine human tissues from 97 A-seq RNA-seq samples. Our findings demonstrate that exhibits different compared to normal tissues, which contributes diverse clinical outcomes cancer We...

10.1101/2023.12.11.571179 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-12-13
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