The aim of this study was to prepare and characterize membranes silk fibroin (SF) chitosan (CHI) blends. Moreover, a conformation transition SF more stable form induced by the addition CHI verified. Blend were prepared, after pH adjustment, in different ratios, physical integrity, crystallinity, structural thermal stability characterized. results crystallographic analysis (XRD) indicated tendency higher organization caused CHI. Fourier transformed infrared spectroscopy (FTIR) showed that is...

In this study, we proposed the use of biopolymers silk fibroin, chitosan and alginate, which are recognized for their biocompatibility biodegradability, preparation multilayer membranes aiming at high performance wound dressings with controlled drug delivery. The rationale was to combine in one material mechanical properties antimicrobial action ideal exudate absorption reaching a synergic effect each biopolymer, without losing individual intrinsic properties. were prepared by casting...

The moisture equilibrium isotherms of chitosan were determined at 20, 30, 40, 50 and 60 °C, using the gravimetric static method. Experimental data analyzed by GAB, Oswin, Halsey Smith equations. Isosteric heat differential entropy sorption from GAB model Clausius-Clapeyron Gibbs-Helmholtz equations, pore size distribution was calculated Kelvin Oswin equations showed best fit to experimental with R2 ≈ 99% low mean relative deviation values (E% < 10%). Monolayer content (from 0.12 0.20 kg...

ABSTRACT Biocomposite membranes from biodegradable and biocompatible natural polymers were prepared sodium alginate solution reinforced with silk fibroin fibers in several fiber content by casting solvent evaporation. The properties of these biocomposites investigated scanning electron microscopy, swelling test, water vapor transmission, mechanical thermal analyses, cytotoxicity test. A biocomposite uniform dispersion good fiber–matrix interaction was obtained through the incorporation...

Chitosan films have been extensively studied as dressings in formulations for the treatment of chronic wounds. The incorporation aloe vera (Aloe barbadensis Miller) into chitosan could potentialize healing process since shows several pharmacological activities. This work aimed to evaluate effect and concentrations on physicochemical properties developed films. were obtained by casting technique characterized with respect their color parameters, morphology, barrier mechanical properties,...

Abstract Silk fibroin has been widely explored for many biomedical applications, due to its biocompatibility and biodegradability. Sterilization is a fundamental step in biomaterials processing it must not jeopardize the functionality of medical devices. The aim this study was analyze influence different sterilization methods physical, chemical, biological characteristics dense porous silk membranes. membranes were treated by several procedures: immersion 70% ethanol solution, ultraviolet...

Silk fibroin has been widely explored for many biomedical applications, due to its biocompatibility and biodegradability. The aim of this work was study the role dialysis freezing on structural conformation, thermal properties morphology silk hydrogels. Hydrogels were prepared after 3 7 days effect analyzed. For that purpose, a part hydrogels underwent at -20 °C 24 h, followed by lyophilization rest kept 8 with further lyophilization. characterized X-ray diffraction (XRD), Fourier...

ABSTRACT The aim of this work was to study the drying Spirulina platensis , evaluating final product characteristics about its phycocyanin content and protein solubility in water. Two techniques were used: spouted bed thin layer. For a bed, cone‐cylindrical geometry chosen, namely type conventional (CSB) jet‐spouted with paste concentration 5%. thin‐layer performed at temperatures 50 60C, load material 4 kg/m 2 tray. dryer CSB demonstrated good functionality, not presenting collapse during...

ABSTRACT Silk hydrogels are interesting materials to be used as matrix in controlled drug delivery devices. However, methods accelerate fibroin gelation and allow the incorporation during hydrogel preparation needed literature. In this article we report of silk with addition several contents ethanol, kinetics, also evaluate potential these matrices for delivery. Chemical conformational properties did not change despite amount ethanol incorporated hydrogel. Hydrogels containing diclofenac...

Miscibility is an important issue in biopolymer blends for analysis of the behavior polymer pairs through detection phase separation and improvement mechanical physical properties blend. This study presents formulation a stable one-phase mixture collagen regenerated silk fibroin (RSF), with highest miscibility ratio between these two macromolecules, inducing electrostatic interactions, using salt ions. For this aim, ternary diagram was experimentally built mixtures, based on observations...

Summary The moisture equilibrium isotherms of garlic and apple were determined at 50, 60 70 °C using the gravimetric static method. experimental data analysed GAB, BET, Henderson–Thompson Oswin equations. isosteric heat differential entropy desorption by applying Clausius–Clapeyron Gibbs–Helmholtz equations, respectively. GAB equation showed best fitting to ( R 2 &gt; 99% E % &lt; 10%). monolayer content values for higher than those studied temperatures; varied from 0.050 0.056 0.107 0.168...

Abstract A microstructured composite material made of collagen hydrogel (matrix) and silk fibroin microfibers (randomly oriented reinforcing fibers) is investigated in order to conjugate the mechanical resistance with suitable biological performance design new scaffolds for vascular tissue engineering. Results show that fibrils have interfacial adhesion, scaffold exhibits improved properties if compared a pure hydrogel. Furthermore, overall improved. magnified image

Abstract Silk fibroin (SF) films have been largely studied as biomaterials due to their biocompatibility and biodegradability. Casting a SF aqueous solution at room temperature is common technique produce relative low cost processing time; however, brittleness solubility in water make them unsuitable for certain biomedical applications. In this study, the incorporation of additives, ethanol glycerin, are presented an alternative both improve mechanical properties decrease water. with...