A5027600989- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Ultrasound in Clinical Applications
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- Trauma Management and Diagnosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory viral infections research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Occupational and environmental lung diseases
- Myasthenia Gravis and Thymoma
- Long-Term Effects of COVID-19
- Pituitary Gland Disorders and Treatments
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Hemostasis and retained surgical items
- Esophageal Cancer Research and Treatment
- Pneumothorax, Barotrauma, Emphysema
- Vascular Procedures and Complications
- Radiomics and Machine Learning in Medical Imaging
- Meningioma and schwannoma management
- Simulation-Based Education in Healthcare
- Venous Thromboembolism Diagnosis and Management
University of Calgary
2019-2025
Harvard University
2023
The University of Texas MD Anderson Cancer Center
2017-2022
Association of Medical Microbiology and Infectious Disease Canada
2022
Pulmonary and Critical Care Associates
2019
Pulmonary Associates
2018
Clínica Alemana
2017
The University of Texas Health Science Center at Houston
2016-2017
Universidad del Desarrollo
2017
Georgetown University
2014
The role of remdesivir in the treatment patients hospital with COVID-19 remains ill defined a global context. World Health Organization Solidarity randomized controlled trial (RCT) evaluated across many countries, Canada enrolling using an expanded data collection format Canadian Treatments for (CATCO) trial. We report on findings, additional demographics, characteristics and clinical outcomes, to explore potential differential effects different health care systems.
<b><i>Background:</i></b> Thoracentesis with cytological examination of pleural fluid is the initial test choice for evaluation effusions in patients suspected malignant effusion (MPE). There limited data on sensitivity thoracentesis stratified by tumor type. A better understanding sensitivities clinical interest, and may guide early appropriate referral biopsy. <b><i>Objective:</i></b> The primary objective was cytology...
Abstract Background Respiratory syncytial virus ( RSV ) lower respiratory tract infection LRTI is associated with high mortality in patients hematologic malignancies HM ). We sought to determine whether allogeneic hematopoietic cell transplant (allo‐ HCT recipients would be at higher risk for 60‐day mortality. Methods examined a retrospective cohort of adults or without treated (n = 154) our institution from 1996‐2013. defined possible as detected only the upper new radiologic infiltrates...
Background: Diagnosis of sarcoidosis often involves endobronchial biopsy (EBB), but studies have shown varying yields for EBB in suspected sarcoidosis, partly due to differences identifying abnormal mucosa under white light (WL). Narrow band imaging (NBI) may assist the visualization mucosa, its role remains be characterized. Methods: Individuals referred were considered enrollment. Bronchoscopy with both WL and NBI was conducted, followed by EBB. The main objectives characterize...
The routine use of computed tomography and lung cancer screening has increased the incidence peripheral pulmonary lesions (PPLs). Sampling may be needed for some nodules. Many new technologies are available to improve diagnostic performance bronchoscopy sampling PPLs, but few comparative trials exist. objective this study was compare with radial endobronchial ultrasound (rEBUS) using an ultrathin bronchoscope (BF-MP190F, Olympus) a non-ultrathin bronchoscope, without rapid on-site evaluation...
Pleuroscopy is the test of choice for patients with suspected malignant pleural effusion and negative cytology. Biopsies malignancy are frequently attributed to non-specific pleuritis, which poses a dilemma in known active malignancy, raising concern false-negative result. Our primary objective was determine outcomes who had non-malignant diagnosis on pleuroscopy.Retrospective review all pleuroscopy cases from January 2005 2015 at our institution conducted. were categorized by histopathology...
The tyrosine kinase inhibitor pazopanib is used for treatment of sarcoma. Recent studies have suggested that the use may lead to development pneumothorax, an unexpected adverse effect in patients with sarcoma metastatic chest.We conducted a retrospective case control study metastases chest pneumothorax (cases) and without (controls). population was selected from tumor registry 1:4 (cases controls) ratio. primary outcome interest association between risk chest. Secondary objective evaluate...
Background: Population aging and lung cancer screening strategies may lead to an increase in detection of early-stage medical inoperable patients. Recent advances peripheral bronchoscopy have made it a suitable platform for ablation small tumors. Methods: We investigated the tissue-ablative effect diode laser bronchoscopically applied by delivery fiber (LDF) with wide aperture on porcine parenchyma. Laser was tested ex vivo identify most effective power settings LDF. Chest computed...
Pleuroscopy with pleural biopsy has a high sensitivity for malignant effusion (MPE). Because MPEs tend to recur, concurrent diagnosis and treatment of MPE during pleuroscopy is desired. However, proceeding directly at the time requires confidence in on-site diagnosis. The study's primary objective was create predictive model estimate probability pleuroscopy.A prospective observational multicentre cohort study consecutive patients undergoing conducted. We used logistic regression evaluate...
Pleural diseases include a spectrum of disorders broadly categorized into pneumothorax and pleural effusion. They often cause pain, breathlessness, cough, reduced quality life. The global burden reflects regional differences in conditions exposures associated with disease, such as smoking, pneumonia, tuberculosis, asbestos, cancer, organ failure. Disease high-income countries is overrepresented given the availability data disease lower-income likely underestimated. In United States, 2016,...
Keywords: Interventional pulmonologylung cancerpleural effusionpulmonary diseasepulmonary fibrosispulmonary nodulerespiratory diseasestaging
Abstract Objective Molecular subtyping of non‐small cell lung cancer (NSCLC) is critical in the diagnostic evaluation patients with advanced disease. This study aimed to examine whether samples from endobronchial ultrasound transbronchial needle aspiration (EBUS‐TBNA) intrathoracic lymph nodes and/or lesions are adequate for molecular analysis across various institutions. Methods We retrospectively reviewed all cases linear EBUS‐TBNA a final bronchoscopic diagnosis NSCLC entered Stather...
The optimal approach to sedation for pleuroscopy remains undefined. Propofol is the favored sedative-hypnotic many proceduralists but has a narrow therapeutic window and risk oversedation high. Propofol-based administered by anesthesiologists routine use of end-tidal capnography bispectral index (BIS) monitoring may attenuate risks complications.The purpose our study was evaluate safety efficacy monitored anesthesia care pleuroscopy.We conducted retrospective cohort patients who underwent...
During diagnostic thoracoscopy, talc pleurodesis after biopsy is appropriate if the probability of malignancy sufficiently high. Findings on direct visual assessment pleura during rapid onsite evaluation (ROSE) touch preparations (touch preps) thoracoscopic specimens, and preoperative imaging may help predict likelihood malignancy; however, data performance these methods are limited.To assess ROSE preps, in diagnosing malignancy.Patients who underwent preps thoracoscopy for suspected were...
The standard approach to staging of lung cancer in patients with pleural effusion (clinical M1a) is thoracentesis followed by biopsies if the cytologic analysis negative. If biopsy findings are negative, endobronchial ultrasound-guided transbronchial needle aspiration used complete process and, some cases, obtain diagnosis. In this case series we report 7 which a combined procedure was performed for known or suspected cancer. We found that both feasible and safe series.