A5035778660- Fungal and yeast genetics research
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Fermentation and Sensory Analysis
- Plant nutrient uptake and metabolism
- Protein Kinase Regulation and GTPase Signaling
- Metabolism, Diabetes, and Cancer
- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Polyamine Metabolism and Applications
- Endoplasmic Reticulum Stress and Disease
- Plant biochemistry and biosynthesis
- Pancreatic function and diabetes
- Catalysis for Biomass Conversion
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- Biotin and Related Studies
- Plant Molecular Biology Research
- Cellular transport and secretion
- Enzyme Catalysis and Immobilization
- Microbial Inactivation Methods
- Probiotics and Fermented Foods
- Plant Gene Expression Analysis
- PI3K/AKT/mTOR signaling in cancer
- Plant Stress Responses and Tolerance
KU Leuven
2015-2024
VIB-KU Leuven Center for Microbiology
2015-2024
Czech Academy of Sciences, Institute of Botany
1999-2024
Novelis (Canada)
2023
Vlaams Instituut voor Biotechnologie
2005-2019
International Center for Tropical Agriculture
2014
VTT Technical Research Centre of Finland
2011
Volgograd Institute of Business
2008
Universidad Autónoma del Estado de Morelos
2004
Universidad Nacional Autónoma de México
2004
The profitability and sustainability of future biorefineries are dependent on efficient feedstock use. Therefore, it is essential to valorize lignin when using wood. We have developed an integrated biorefinery that converts 78 weight % (wt %) birch into xylochemicals. Reductive catalytic fractionation the wood produces a carbohydrate pulp amenable bioethanol production oil. After extraction oil, crude, unseparated mixture phenolic monomers catalytically funneled 20 wt phenol 9 propylene (on...
The yeast Saccharomyces cerevisiae responds to osmotic stress, i.e., an increase in osmolarity of the growth medium, by enhanced production and intracellular accumulation glycerol as a compatible solute. We have cloned gene encoding key enzyme synthesis, NADH-dependent cytosolic glycerol-3-phosphate dehydrogenase, we named it GPD1. gpd1 delta mutants produced very little glycerol, they were sensitive stress. Thus, is indeed essential for cells during reduced water availability. hog1 lacking...
We have analyzed the transcriptional response to osmotic shock in yeast <i>Saccharomyces cerevisiae</i>. The mRNA level of 186 genes increased at least 3-fold after a shift NaCl or sorbitol, whereas that more than 100 was 1.5-fold diminished. Many induced encode proteins presumably contribute protection against different types damage enzymes glycerol, trehalose, and glycogen metabolism. Several genes, which poorly expressed isoforms carbohydrate metabolism, were induced. high osmolarity...
The yeast Saccharomyces cerevisiae responds to osmotic stress, i.e., an increase in osmolarity of the growth medium, by enhanced production and intracellular accumulation glycerol as a compatible solute. We have cloned gene encoding key enzyme synthesis, NADH-dependent cytosolic glycerol-3-phosphate dehydrogenase, we named it GPD1. gpd1 delta mutants produced very little glycerol, they were sensitive stress. Thus, is indeed essential for cells during reduced water availability. hog1 lacking...
ABSTRACT Volatile esters are responsible for the fruity character of fermented beverages and thus constitute a vital group aromatic compounds in beer wine. Many fermentation parameters known to affect volatile ester production. In order obtain insight into production ethyl during fermentation, we investigated influence several variables. A higher level unsaturated fatty acids medium resulted general decrease On other hand, temperature greater octanoate decanoate production, while carbon or...
Abstract In Arabidopsis (Arabidopsis thaliana), trehalose is present at almost undetectable levels, excluding its role as an osmoprotectant. Here, we report that overexpression of AtTPS1 in using the 35S promoter led to a small increase and trehalose-6-P levels. spite this, transgenic plants displayed dehydration tolerance phenotype without any visible morphological alterations, except for delayed flowering. Moreover, seedlings overexpressing exhibited glucose (Glc)- abscisic acid...
The production of bioethanol from lignocellulose hydrolysates requires a robust, D-xylose-fermenting and inhibitor-tolerant microorganism as catalyst. purpose the present work was to develop such strain prime industrial yeast strain, Ethanol Red, used for production.An expression cassette containing 13 genes including Clostridium phytofermentans XylA, encoding D-xylose isomerase (XI), enzymes pentose phosphate pathway inserted in two copies genome Red. Subsequent EMS mutagenesis, shuffling...
Elucidation of the catalyst role during reductive catalytic fractionation, enabling integration lignin valorization and bio-ethanol production.
The phytohormones jasmonates (JAs) constitute an important class of elicitors for many plant secondary metabolic pathways. However, JAs do not act independently but operate in complex networks with crosstalk to several other phytohormonal signaling Here, was detected between the JA and abscisic acid (ABA) pathways regulation tobacco ( Nicotiana tabacum ) alkaloid biosynthesis. A gene from PYR/PYL/RCAR family, NtPYL4 , expression which is regulated by JAs, found encode a functional ABA...
Significance Saponins are plant molecules that produced as a chemical defense against herbivores and eukaryotic pathogens. They constitute structurally diverse, bioactive compounds composed of 30-carbon triterpene backbone adorned with multiple functional groups sugars. Saikosaponins abundant saponins accumulating in the Asian medicinal Bupleurum falcatum , but none enzymes involved their biosynthesis had been characterized. We identified cytochrome P450 oxidation saikosaponins, thereby...