A5076885268- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Pancreatic and Hepatic Oncology Research
- Cancer and Skin Lesions
- Cancer Treatment and Pharmacology
- Thyroid Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Breast Implant and Reconstruction
- Genetic factors in colorectal cancer
- Colorectal Cancer Surgical Treatments
- Neutropenia and Cancer Infections
- Airway Management and Intubation Techniques
- Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple and Secondary Primary Cancers
- Sperm and Testicular Function
- Radiomics and Machine Learning in Medical Imaging
- Hemostasis and retained surgical items
- Renal cell carcinoma treatment
- Thyroid Disorders and Treatments
- Bariatric Surgery and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
University of Palermo
2008-2021
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2001-2021
Ospedale D. Cotugno
2007
Weatherford College
1993
Several studies report a higher rate of papillary thyroid carcinomas (PTC) in patients with Hashimoto thyroiditis (HT), indicating possible correlation between the two diseases. We studied group 89 subjects undergoing surgery for compared control operated on normofunctioning goiter, and second 47 total thyroidectomy HT. Association HT was found 19 71 PTC (26.7%) 8 goiter (8.9%), which significant difference ( P < 0.02). Thirteen patients, mostly nodular form, showed coexistent (27.6%)....
The association between Hashimoto's thyroiditis (HT) and papillary thyroid carcinoma (PTC) is a controversial question that still under debate, its pathological significance the eventual clinical implications of this remaining unclear.The data regarding 305 patients were retrospectively analyzed. divided in two different groups. A first group made up 142 undergoing surgery for differentiated was compared to control analogous subjects operated normofunctioning goiter. second 163 who had...
Objective: To evaluate BRAFV600E mutation on consecutive fine-needle aspiration biopsy (FNAB) specimens in order to assess FNAB's usefulness preoperative papillary thyroid carcinoma (PTC) diagnosis with the contemporaneous analysis of RET/PTC1 and RET/PTC3 rearrangements obtained from ex vivo nodules. Design: Thyroid FNABs 156 subjects nodules 49 corresponding surgical samples were examined for presence BRAF by real-time allele-specific polymerase chain reaction, confirmed use a laser...
Summary Background A major problem in assessing the likelihood of survival patients with hepatocellular carcinoma (HCC) arises from a lack models capable predicting outcome accurately. Aim To compare ability Italian score (CLIP), French classification (GRETCH) and Barcelona (BCLC) staging system HCC. Methods We included 406 consecutive cirrhosis Seventy‐eight per cent had hepatitis C. Independent predictors were identified using Cox model. Results One‐hundred seventy‐eight treated, while 228...
BRAF V600E is the most common mutation found in papillary thyroid carcinoma (PTC). Tissue inhibitor of metalloproteinases (TIMP-1) and nuclear factor (NF)-κB have been shown to play an important role cancer. In particular, TIMP-1 binds its receptor CD63 on cell surface membrane activates Akt signaling pathway, which eventually responsible for anti-apoptotic activity. The aim our study was evaluate whether interplay among these three factors exists exerts a functional PTCs. To this purpose,...
Abstract Background Seroma formation frequently occurs in patients who have undergone axillary lymphadenectomy. The aim of the study was to evaluate effect fibrin glue prevention seroma after Materials and Methods Hundred fifty‐nine breast cancer about undergo quadrantectomy or mastectomy plus lymphadenectomy were enrolled randomized into two groups. Fibrin spray applied fossa placement closed suction drainage used 80 (group A); only 79 B). Results Group A showed a slight advantage with...
Forty patients with chemotherapy-related diarrhea were randomized to receive (i) octreotide 0.5 mg three times per day s.c. or (ii) loperamide 4 p.o. until complete remission of was achieved. In the group 80% showed resolution loose bowel movements within days therapy, while in this goal obtained only 30% cases (p < 0.001). If after no benefit seen, considered have failed antidiarrheal therapy. Failure recorded one case (5%) treated and five (25%) who received loperamide. The mean duration...
Secretory mammary carcinoma is a rare breast neoplasia originally described in children but sometimes also found adults. It presents more favourable outcome than common histological types of carcinoma; published literature fact reports only few cases with axillary lymph node metastases and four distant metastases. In this paper we report case secretory 33-year-old woman. To our knowledge, the first involving biopsy sentinel investigation e-cadherin expression. We positivity for e-cadherin,...
Background Preoperative lymphoscintigraphy is without doubt a valid method for the detection of sentinel lymph node (SLN). There has been considerable debate regarding optimal site introduction tracer; various sites include peritumoral (PT), periareolar (PA), subdermal, and intradermal injection. Purpose To evaluate retrospectively lymphoscintigraphic identification rate (PT) injection versus subdermal (PA) in SLNs breast cancer. Material Methods Between October 2002 December 2011, cohort...
The aim of this study was to evaluate the current role frozen section in identifying patients who could benefit from an immediate axillary lymph node dissection (ALND), following criteria ASOCOG Z0011 and IBCSG 23-10 trials.A retrospective review performed involving 2,079 with early breast cancer underwent conservative surgery or total mastectomy sentinel biopsy.Sensitivity diagnostic accuracy were 63.8% 90.3%, respectively. Sensitivity significantly higher (p<0.001) finding macrometastases...
Thyroidectomy is the preferred approach as definitive treatment for Graves' disease. The outcomes total thyroidectomy in a large series of 594 patients, who were observed last decade, will be presented this study.The study concerned retrospective review undergoing incidence complications and on hyperthyroidism correlated symptoms resolution also evaluated.The mean age patients was 44.7 ± 12.7 years 456 (76.7%) females. gland weight 67.3 10.8 g (range: 20-350 g) and, 397 (66.8%), weighed >40...
The prognostic value of DNA ploidy, S-phase fraction (SPF) and K-ras-2 mutations in gastric carcinoma (GC) has not yet been clearly defined. aim this study was to clarify the association between biomolecular variables, tumor characteristics, clinical outcome GC patients.Resected specimens from a consecutive series 69 patients with who underwent potentially curative surgery were studied prospectively. ploidy SPF assessed by flow cytometry on multiple frozen samples, whereas detected...