A5112572905- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Bone Tissue Engineering Materials
- Respiratory and Cough-Related Research
- 3D Printing in Biomedical Research
- Muscle Physiology and Disorders
- Forensic Toxicology and Drug Analysis
- Asthma and respiratory diseases
- Opioid Use Disorder Treatment
- Knee injuries and reconstruction techniques
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Ion Channels and Receptors
- Peripheral Artery Disease Management
- Circadian rhythm and melatonin
- Osteoarthritis Treatment and Mechanisms
- Diabetic Foot Ulcer Assessment and Management
- Nerve injury and regeneration
- Cerebral Palsy and Movement Disorders
- Nutrition and Health in Aging
- Orthopedic Infections and Treatments
- Additive Manufacturing and 3D Printing Technologies
- Poisoning and overdose treatments
- Trace Elements in Health
- Tissue Engineering and Regenerative Medicine
Nanjing Drum Tower Hospital
2020-2024
Southeast University
2016-2024
Chinese University of Hong Kong
2024
Prince of Wales Hospital
2024
Nanjing Medical University
2022
Nanjing University
2020-2022
Model Animal Research Center
2020-2021
Biomaterial-based scaffolds fabricated by electrospinning technique are promising platforms for bone tissue engineering. However, the current have some limitations in terms of poor osteogenic bioactivities. In this study, citrate-stabilized gold-nanoparticles (GNPs) were encapsulated into polyvinylpyrrolidone/ethylcellulose coaxial technique. Three types GNPs-loaded electrospun (P/E-0.5, P/E-1, and P/E-1.5) prepared changing feeding GNPs. The morphological physicochemical properties these...
Mesenchymal stem cells (MSCs) can be effective in alleviating the progression of osteoarthritis (OA). However, low MSC retention and survival at injection site frequently require high doses and/or repeated injections, which are not economically viable create additional risks complications. In this study, we produced MSC-laden microcarriers spinner flask culture as cell delivery vehicles. These containing a initial dose MSCs administered through single rat anterior cruciate ligament (ACL)...
Injectable hydrogels offer a new therapy option for irregular bone deformities. Based on gelatin methacryloyl (GelMA), marrow mesenchymal stem cells (BMSCs), and morphogenetic protein 2 (BMP2), we created photo-crosslinked composite bioactive scaffold. The scaffolds had appropriate mechanical properties adhesion proliferation, as well good biocompatibility the ability to stimulate BMSCs osteogenic differentiation in vitro. synergistic effect of BMP2 enabled scaffold exhibit higher potential...
Abstract Background Deep vein thrombosis (DVT) has been one of the most dangerous complications in total hip arthroplasty (THA). If a patient’s pre-surgical DVT is overlooked, it can easily be mistaken for post-operative thrombus and lead to an increased risk during after surgery. This retrospective study was explore incidence associated factors deep non-fracture patients before Methods From September 2015 2020, 1242 admitted THA were enrolled with 1120 (90.2%) primary 122 (9.8%) revision...
Abstract Neuromuscular junction (NMJ) degeneration is one of pathological factors sarcopenia. Low‐magnitude high‐frequency vibration (LMHFV) was reported effective in alleviating the sarcopenia progress. However, no previous study has investigated treatment effects LMHFV targeting NMJ We first compared morphological differences between sarcopenic and non‐sarcopenic subjects, as well young old C57BL/6 mice. then systematically characterized age‐related SAMP8 against its control strain, SAMR1...
To evaluate the accuracy and safety of LANCET robotic system, a robot arm assisted operation system for total hip arthroplasty via multicenter clinical randomized controlled trial. A 116 patients were into two groups: THA group (N = 58) conventional 58). General information about was collected preoperatively. Operational time bleeding recorded during surgery. The position acetabular prosthesis evaluated by radiographs one week after surgery compared with preoperative planning. Harris score,...
The aim of this study was to investigate the effects melatonin on oxidative stress, expression transient receptor potential melastatin-2 (TRPM2) in guinea pig brains, and influence stress lungs airway inflammation induced by particulate matter 2.5 (PM2.5). A particle suspension (0.1 g/ml) nasally administered pigs prepare a PM2.5 exposure model. Cough frequency cough incubation period were determined through RM6240B biological signal collection disposal system. Oxidative markers, including...
Background: Deep Vein Thrombosis (DVT) is a common disease, frequently afflicting the lower limb veins of bedridden patients. Intermittent Pneumatic Compression (IPC) often employed as an effective solution for this problem. In our study, random selection 264 patients underwent IPC treatment either one or 8 hours daily. The rate severe venous thrombosis was substantially reduced in IPC-treated group compared to control group. However, real-time monitoring blood flow during operation periods...
The study aimed to examine the impact of melatonin on mitigating brain inflammation and cough sensitivity resulting from exposure particulate matter 2.5 (PM2.5). Guinea pigs were randomly assigned blank control group, normal saline PM2.5 + group. groups given intranasal instillations suspension twice daily for 28 consecutive days. Starting day 21, group was treated with an intraperitoneal injection at 10 pm. Cough citric acid, microglia activation, IL-1β TNF-α levels in airway dorsal vagal...
To analyze the changes of lower limb hemodynamics parameters before and after wearing graduated compression stockings (GCS) during ankle pump exercise in patients preparing for arthroplastic surgery.The leg veins 16 awaiting arthroplasty were analyzed using a Sonosite M-Turbo ultrasound system with or without GCS. The age them was 70 ± 7 years (mean SD) (range 56-82 years) body mass index 25.8 3.0 kg/m2 18.0-30.5 kg/m2). Measured data including cross-sectional area (CSA), anteroposterior...
Abstract Deep vein thrombosis (DVT) is a common disease often occurring in the lower limb veins of bedridden patients. Intermittent pneumatic compression (IPC) has been considered an effective approach to solve this problem. In our previous research, 264 patients were randomly treated either with IPC for one or eight hours per day. The incidence severe venous was significantly lowered group than control group. However, it still chanllenge real-time monitoring blood flow and thrombus...
Abstract Objectives: To analyze the changes of lower limb hemodynamics parameters before and after wearing graduated compression stockings (GCS) during ankle pump exercise in patients preparing for arthroplastic surgery. Method: The leg veins 16 awaiting arthroplasty were analyzed using a Sonosite M-Turbo ultrasound system with or without GCS. Measured data including cross-sectional area (CSA), anteroposterior (AP) diameter lateromedial (LM) soleus vein (SV), posterior tibial (PTV) great...