Tong Zheng

ORCID: 0000-0002-2666-7618
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About
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Research Areas
  • Total Knee Arthroplasty Outcomes
  • Knee injuries and reconstruction techniques
  • Sports injuries and prevention
  • Lower Extremity Biomechanics and Pathologies
  • Foot and Ankle Surgery
  • Shoulder Injury and Treatment
  • Orthopedic Surgery and Rehabilitation
  • Hip disorders and treatments
  • Tendon Structure and Treatment
  • Ubiquitin and proteasome pathways
  • Spacecraft and Cryogenic Technologies
  • Renal and related cancers
  • Epigenetics and DNA Methylation
  • Bone fractures and treatments
  • Elbow and Forearm Trauma Treatment
  • Fluid Dynamics and Heat Transfer
  • Musculoskeletal synovial abnormalities and treatments
  • Shoulder and Clavicle Injuries
  • Chronic Kidney Disease and Diabetes
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Adhesion, Friction, and Surface Interactions
  • Cancer, Hypoxia, and Metabolism
  • Gout, Hyperuricemia, Uric Acid
  • Intracerebral and Subarachnoid Hemorrhage Research

Dalian University of Technology
2025

Peking University
2018-2024

Beijing Jishuitan Hospital
2019-2024

Capital Medical University
2023-2024

Northeastern University
2024

Third Affiliated Hospital of Sun Yat-sen University
2021-2023

Sun Yat-sen University
2021-2023

Harbin Institute of Technology
2023

China Earthquake Administration
2023

Technology and Engineering Center for Space Utilization
2022

Background: Steep posterior tibial slope (PTS; >13°), excessive anterior subluxation (ATS) in extension (>10 mm), and meniscus horn tears (MPHTs) have been identified to be associated with primary cruciate ligament (ACL) reconstruction (ACLR) failure. Recent studies reported that steep PTS is directly correlated ATS concomitant MPHTs, especially for those patients chronic (>6 months) ACL deficiency. There increasing biomechanical evidence slope-reducing osteotomy decreases protects...

10.1177/0363546520963083 article EN The American Journal of Sports Medicine 2020-10-28

Background: It has been speculated that the patellar J sign may have a negative effect on clinical outcomes of patients with recurrent dislocation (RPD). Purpose: To (1) evaluate outcomes, postoperative stability, and maltracking correction in RPD treated derotational distal femoral osteotomy (DDFO) combined procedures (2) investigate influence severity outcomes. Study Design: Cohort study; Level evidence, 3. Methods: Between January 2015 December 2016, total 78 (81 knees) RPD, positive...

10.1177/0363546519884669 article EN The American Journal of Sports Medicine 2019-11-25

Background: Steep posterior tibial slope (PTS) and excessive anterior translation (ATT) have been identified as important anatomic risk factors for cruciate ligament (ACL) injury, which raised concerns about clinical outcomes after primary ACL reconstruction (ACLR). Purpose: To investigate of ACLR failure to determine the cutoff values PTS ATT predicting failure. Study Design: Case-control study; Level evidence, 3. Methods: Between November 2015 May 2017, a total 215 consecutive patients...

10.1177/0363546520949212 article EN The American Journal of Sports Medicine 2020-08-31

The lateral meniscus posterior root (LMPR) lesion further decreases dynamic knee stability after anterior cruciate ligament (ACL) injury owing to the loss of "wedge effect" maintained by horn meniscus. However, effect LMPR lesions on static tibiofemoral relationship in extension ACL injuries is not determined.To (1) determine tibial subluxation compartment (ATSLC) patients with and (2) identify LMPR-related factors associated excessive ATSLC extension.Cohort study; Level evidence, 3.Between...

10.1177/0363546520902150 article EN The American Journal of Sports Medicine 2020-02-14

Controversy exists regarding the surgical treatment of recurrent patellar dislocation (RPD) with an increased femoral anteversion angle (FAA). Medial patellofemoral ligament reconstruction (MPFL-R) either alone or combined derotational distal osteotomy (DDFO) results in favorable clinical outcomes.To compare outcomes MPFL-R versus DDFO treating RPD FAA (>30°).Cohort study; Level evidence, 3.Between January 2014 and December 2017, 126 patients (135 knees) (>30°) were surgically treated using...

10.1177/0363546520968566 article EN The American Journal of Sports Medicine 2020-11-12

Background: Derotational distal femoral osteotomy (DDFO) has been used to treat patients with recurrent patellar dislocation (RPD) increased anteversion. However, no study reported second-look arthroscopic findings in the patellofemoral joint after DDFO. Purpose: To report clinical and outcomes for DDFO combined medial ligament reconstruction (MPFL-R) treating RPD Study Design: Case series; Level of evidence, 4. Methods: From 2015 2019, 131 consecutive (144 knees) were treated MPFL-R...

10.1177/03635465221147484 article EN The American Journal of Sports Medicine 2023-01-20

Dropwise condensation offers substantial heat transfer advantages over filmwise condensation, enhancing the industrial condenser efficiency and reducing energy losses. However, dynamics of condensate droplets on horizontal tube bundles remains complex insufficiently studied. This paper presents a detailed investigation impact dynamic behaviors by numerical simulation using Volume Fluid model. The droplet Weber number (Wed) between determines characteristics behaviors. study examines effects...

10.1021/acs.langmuir.4c04489 article EN Langmuir 2025-01-30

NLRP3, a decisive role in inflammation regulation, is obviously upregulated by oxidative stress kidney injury. The NLRP3 upregulation leads to unsolved and other pathological effects, contributing aggravation of injury even transition chronic disease (CKD). However, the mechanism for further remains largely elusive. In this study, we found 3'UTR was shortened response vivo vitro. Functionally, such shortening expression amplified inflammation, fibrogenesis, ROS production apoptosis,...

10.1038/s41419-021-03751-3 article EN cc-by Cell Death and Disease 2021-05-19

Alternative polyadenylation (APA), a posttranscriptional mechanism of gene expression via determination 3'UTR length, has an emerging role in carcinogenesis. Although abundant APA reprogramming is found kidney renal clear cell carcinoma (KIRC), which one the major malignancies, whether functions KIRC remains unknown. Herein, we that chromatin modifier MORC2 gained oncogenic potential among genes with reprogramming, and moreover, its was enhanced by shortening through stabilization mRNA. to...

10.1172/jci.insight.162893 article EN cc-by JCI Insight 2023-09-21

Background: Anterior tibial subluxation (ATS) in extension after anterior cruciate ligament (ACL) injury highlights an increased position of the tibia relative to femur. Recent studies demonstrated that is sometimes irreducible and normal tibiofemoral relationship not restored by ACL reconstruction (ACLR), which raises concerns regarding clinical outcomes ACLR. Hypothesis: Excessive preoperative ATS associated with inferior knee stability anatomic Study Design: Cohort study; Level evidence,...

10.1177/0363546519900158 article EN The American Journal of Sports Medicine 2020-02-06

Abstract Objective The purpose of this study was to analyze the relationship between tibiofemoral rotation and patellar maltracking in patients with recurrent dislocation. Methods A total 143 consecutive knees (118 patients) clinically diagnosed dislocation from January 2018 December 2019 were retrospectively analyzed. Patellar tilt angle bisect offset index recorded on axial CT assesses severity maltracking. Tibiofemoral is measured by comparing posterior femoral tibial condylar lines...

10.1111/os.13358 article EN Orthopaedic Surgery 2022-06-13
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