A5100723152- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Advanced X-ray Imaging Techniques
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Laser-Plasma Interactions and Diagnostics
- Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Tracheal and airway disorders
- Cell Adhesion Molecules Research
- Proteoglycans and glycosaminoglycans research
- Digital Radiography and Breast Imaging
- X-ray Spectroscopy and Fluorescence Analysis
- Radiation Dose and Imaging
- RNA modifications and cancer
- Protease and Inhibitor Mechanisms
- Advanced Sensor and Energy Harvesting Materials
- Autophagy in Disease and Therapy
- Electrical and Bioimpedance Tomography
- Ferroelectric and Piezoelectric Materials
- Cell death mechanisms and regulation
University of Nottingham Ningbo China
2025
Beihang University
2015-2025
Inserm
2025
Centre de recherche en Epidémiologie et Santé des Populations
2025
NRG Oncology
2025
Université Paris-Saclay
2025
Jiangsu University
2017-2025
Affiliated Hospital of Jiangsu University
2017-2025
Hefei University of Technology
2022-2024
Ningbo University of Technology
2020-2024
Endorepellin, the COOH-terminal domain of heparan sulfate proteoglycan perlecan, inhibits several aspects angiogenesis. We provide evidence for a novel biological axis that links soluble fragment perlecan protein core to major cell surface receptor collagen I, α2β1 integrin, and an initial investigation intracellular signaling events lead endorepellin antiangiogenic activity. The interaction between integrin triggers unique pathway causes increase in second messenger cAMP; activation two...
Perlecan, a ubiquitous basement membrane heparan sulfate proteoglycan, plays key roles in blood vessel growth and structural integrity. We discovered that the C terminus of perlecan potently inhibited four aspects angiogenesis: endothelial cell migration, collagen-induced tube morphogenesis, chorioallantoic Matrigel plug assays. The was active at nanomolar concentrations blocked adhesion to fibronectin type I collagen, without directly binding either protein; henceforth we have named it...
Endorepellin, the COOH-terminal domain of heparan sulfate proteoglycan perlecan, inhibits several aspects angiogenesis. We provide evidence for a novel biological axis that links soluble fragment perlecan protein core to major cell surface receptor collagen I, α2β1 integrin, and an initial investigation intracellular signaling events lead endorepellin antiangiogenic activity. The interaction between integrin triggers unique pathway causes increase in second messenger cAMP; activation two...
Endorepellin, the C-terminal domain of heparan sulfate proteoglycan perlecan, possesses angiostatic activity. The terminal laminin-like globular (LG3) endorepellin appears to possess most biological activity on endothelial cells. LG3 protein has been detected in urine patients with end-stage renal disease and amniotic fluid pregnant women premature rupture fetal membranes. These findings suggest that proteolytic processing generation might have significance. In this study, we identified...
Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often. Conventional reconstruction algorithms are not easy to deal data. They usually involved complicated parameter selection operations, also sensitive noise time-consuming. In this paper, we reported new deep learning framework data DPC-CT. It tight coupling of neural...
Relaxor ferroelectrics are highly desired for pulse-power dielectric capacitors, however it has become a bottleneck that substantial enhancements of energy density generally sacrifice efficiency under superhigh fields. Here, we demonstrate novel concept polarizable concentrated dipole glass in delicately-designed high-entropy (Bi
The goal of this study was to discover novel partners for perlecan, a major heparan sulfate proteoglycan basement membranes, and examine new interactions through which perlecan may influence cell behavior. We employed the yeast two-hybrid system used domain V as bait screen human keratinocyte cDNA library. Among strongest interacting clones, we isolated ∼1.6-kb insert that encoded extracellular matrix protein 1 (ECM1), secreted glycoprotein involved in bone formation angiogenesis. sequencing...
Breast cancer is a major threat to health and lives of females. Biomimetic nanotechnology brought brighter hope for early diagnosis treatment breast cancer. Here, we proposed platelet (PLT) membrane-derived strategy enhanced photoacoustic (PA)/ultrasonic (US)/fluorescence (FL) multimodal imaging augmented synergistic photothermal/chemotherapeutic efficacy in tumor cells. A PA contrast photothermal agent, nanocarbons (CNs), chemotherapeutic FL material, doxorubicin (DOX), perfluoropentane...
Wearable sweat sensors are a rapidly rising research area owing to their convenience for personal healthcare and disease diagnosis in real-time noninvasive manner. However, the fast scalable fabrication of flexible electrodes remains major challenge. Here, we develop wearable epidermal sensor multiplexed analysis based on laser-induced graphene (LIG) technique. This simple mask-free technique allows direct manufacturing electrode patterns commercial polyimide foils. The resulting LIG devices...
<title>Abstract</title> Background Recurrent hemoptysis after bronchial artery embolization (BAE) in patients with bronchiectasis remains a major clinical challenge. The Computed Tomography Bronchiectasis Score (CTBS) quantifies disease severity based on radiological characteristics. This study aims to assess the prognostic value of CTBS predicting 3-year recurrence following BAE bronchiectasis. Methods retrospective cohort included 121 who underwent for bronchiectasis-related from January...
Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often. Conventional reconstruction algorithms face difficulty when given data. They usually involve complicated parameter selection operations, which are also sensitive to noise time-consuming. In this paper, we report new deep learning framework data DPC-CT. It involves...
To evaluate whether preoperative mean corpuscular volume (MCV) is a prognostic indicator in patients with resectable esophageal squamous cell carcinoma (ESCC).A total of 298 consecutive, prospectively enrolled histologically diagnosed ESCC who underwent surgery curative intent from 2001 to 2011 were retrospectively evaluated. Patients excluded if they had previous malignant disease, distant metastasis at the time primary treatment, history neoadjuvant undergone non-radical resection, or died...
Objective This study was conducted to examine the causal association between exercise and risk of dementia among older Chinese adults. Design Longitudinal population-based with a follow-up duration 9 years. Setting Data for Healthy Longevity Survey waves occurring from 2002 2011–2012 were extracted survey database. Participants In total, 7501 dementia-free subjects who than 65 years included at baseline. Dementia defined as self-reported or proxy-reported physician’s diagnosis disease....
Objective: The objective of this study was to explore the association between social engagement and cognitive impairment with psychological well-being (PWB) as a mediator in older Chinese adults further test gender differences association. Method: Data were drawn from Longitudinal Healthy Longevity Survey adults, aged 65 ( N = 6,998). total effect decomposed into direct indirect effects by logistic regression based on Karlson, Holm, Breen method. Results: Higher significantly associated...
Aero engines are the key power source for aerospace vehicles. Cermet turbine blades guarantee new-generation fighters to improve aero-engine overall performance. X-ray non-destructive reconstruction can obtain internal structure and morphology of cermet blades. However, beam hardening effect causes artifacts in objects affects quality, which is an issue that needs be solved urgently. This study proposes a hardening-correction framework industrial computed tomography (ICT) images based on...
To evaluate percutaneous laser ablation in treating benign thyroid nodules, we conducted a meta-analysis based on summarizing existing researches.A literature search for clinical trial was performed PubMed, Cochrane Library and Excerpt Medica Database. The qualities of included studies were evaluated. We calculated the indexes with mean difference. Heterogeneity publication bias tested explored. subgroup analyses sensitivity analysis further.A total 19 researches 2137 patients this...
Wearable sweat sensors are a rapidly rising research area owing to their convenience for personal healthcare and disease diagnosis in real-time noninvasive manner. However, the fast scalable fabrication of flexible electrodes remains major challenge. Here, we develop wearable epidermal sensor multiplexed analysis based on laser-induced graphene (LIG) technique. This simple mask-free technique allows direct manufacturing electrode pattern commercial polyimide foils. The resulting LIG devices...
AIM:To compare postoperative complications and prognosis of esophageal squamous cell carcinoma patients treated with different routes reconstruction. METHODS:After obtaining approval from the Medical Ethics Committee Sun Yat-Sen University Cancer Center, we retrospectively reviewed data 306 consecutive histologically diagnosed who were between 2001 2011.All underwent radical McKeown-type esophagectomy at least two-field lymphadenectomy.Regular follow-up was performed in our outpatient...
Iterative reconstruction has a wide spectrum of proven advantages in the field conventional X-ray absorption-based computed tomography (CT). In this paper, we report on an algebraic iterative technique for grating-based differential phase-contrast CT (DPC-CT). Due to nature DPC-CT projections, operator and smoothing are added reconstruction, compared one commonly used data. This work comprises numerical study algorithm its experimental verification using dataset measured at two-grating...