- Cannabis and Cannabinoid Research
- Diet and metabolism studies
- Sports Performance and Training
- Autoimmune and Inflammatory Disorders Research
- Multiple Sclerosis Research Studies
- Adipose Tissue and Metabolism
- Sports injuries and prevention
- Muscle metabolism and nutrition
- Lower Extremity Biomechanics and Pathologies
- Cancer survivorship and care
- Exercise and Physiological Responses
- Genetics, Aging, and Longevity in Model Organisms
- Fibroblast Growth Factor Research
- Childhood Cancer Survivors' Quality of Life
- Cancer-related cognitive impairment studies
- Cancer, Hypoxia, and Metabolism
- Sleep and related disorders
- Rheumatoid Arthritis Research and Therapies
- Muscle activation and electromyography studies
- Biochemical effects in animals
- Regulation of Appetite and Obesity
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Epigenetics and DNA Methylation
- Motor Control and Adaptation
- Immune Cell Function and Interaction
University of Wisconsin–Madison
2020-2024
The University of Texas Medical Branch at Galveston
2023-2024
University of Illinois Chicago
2023
University of Northern Colorado
2020-2023
Foundation for Physical Medicine and Rehabilitation
2023
William S. Middleton Memorial Veterans Hospital
2021-2022
California State University, Long Beach
2018-2020
Institute for Social Security and Services for State Workers
2020
Sacramento City Unified School District
2019
e-Therapeutics (United Kingdom)
2017
Abstract Low‐protein (LP) diets are associated with a decreased risk of diabetes in humans, and promote leanness glycaemic control both rodents humans. While the effects an LP diet on mediated by reduced levels branched‐chain amino acids, we have observed that reducing dietary other six essential acids leads to changes body composition. Here, find histidine plays key role response male C57BL/6J mice. Specifically 67% reduces weight gain young, lean mice, adipose mass without altering glucose...
There is a lack of research on the effects cannabidiol (CBD) health-related fitness, physical activity, cognitive health, psychological wellbeing, and concentrations C-reactive protein (CRP) in healthy individuals. CBD has potential anti-inflammatory neuroprotective effects.
The endocannabinoid system is active in nervous and immune cells involves the expression of two cannabinoid receptor genes (CB1 CB2), along with endogenous ligands, 2-arachidonoyl glycerol (2-AG) arachidonoyl ethanolamide (anandamide), their synthetic enzymes. Cannabidiol (CBD) a non-intoxicating exogenous agonist derived from plants that, at high doses, has received FDA approval as an anticonvulsant for epileptic seizures, low doses marketed food-grade supplement improved mental health,...
Abstract Flores, V, Becker, J, Burkhardt, E, and Cotter, J. Knee kinetics during squats of varying loads depths in recreationally trained women. J Strength Cond Res 34(7): 1945–1952, 2020—The back squat exercise is typically practiced with barbell loads. However, depth has been inconsistently defined, resulting unclear safety precautions when squatting In addition, women exhibit anatomical kinematic differences to men, which may predispose them knee joint injuries. The purpose this study was...
Fatigue, stress, and depression contribute to poor health-related quality of life (HRQoL) among cancer survivors. This study examined the effects combined aerobic resistance training (CART) on HRQoL biomarkers stress. Cancer survivors (n = 76, 91% female, 39% breast cancer, 32% gynecologic cancer) were enrolled in CART for three 60-min sessions, weekly, 26 weeks. Participants completed National Institutes Health's Patient Reported Outcomes Measurement Information System (NIH PROMIS) fatigue...
Abstract The amino acid composition of the diet has recently emerged as a critical regulator metabolic health. Consumption branched-chain isoleucine is positively correlated with body mass index in humans, and reducing dietary levels rapidly improves health diet-induced obese male C57BL/6J mice. However, it unknown how sex, strain, intake may interact to impact response Western Diet (WD). Here, we find that although magnitude effect varies by sex protects DBA/2J mice both sexes from...
Abstract Aim Duration of untreated psychosis, or the time between onset psychosis symptoms and accurate diagnosis treatment, is a significant predictor both initial treatment response long‐term outcomes. As such, efforts to improve rapid identification are key. Because early signs commonly emerge in adolescence, schools have potential play an important role psychosis‐spectrum disorders. Methods To illustrate this effort, current paper describes implementation screening tool as part larger...
Introduction: This study evaluated depression, monocyte phenotype, and immune function in physically active cannabis users. Methods: Participants (N = 23) were classified as either users (CU, n 11) or non-users (NU, 12). White blood cells isolated from analyzed for co-expression of cluster differentiation 14 16 using flow cytometry. Lipopolysaccharide (LPS) was cultured with whole assessed interleukin-6 tumor necrosis factor-α (TNF-α) release. Results: The percentage white monocytes not...
Abstract Back squats are a common strengthening exercise for knee and hip musculature. However, repetitive loaded movements like backs result in high patellofemoral joint loading therefore may contribute to the development of overuse injuries. Thus, it is important understand how changing parameters such as squat depth or load influences loading. This study investigated differences when experienced female lifters squatted three depths (above parallel, below parallel) with loads (unloaded,...
Curcumin may improve athletic performance through a reduction in inflammation following exercise and mental states of well-being. The purpose this investigation was to explore the effects 14 day HIIT intervention oral supplementation with Longvida® optimized curcumin on performance, lactate response, Sixteen males twenty females participated double-blinded, randomized, placebo-controlled trial Longvida(R) (1.0 g/day) or placebo (PLA) taken daily during protocol. Participants were randomized...
The purpose of this cross-sectional study was to explore physical activity, depression, fatigue, and quality life (QOL), their relationship brain-derived neurotrophic factor (BDNF) nerve growth (NGF) in cancer survivors enrolled a structured exercise program. Participants were recruited into two groups: in-treatment (IT), currently receiving chemotherapy and/or radiotherapy, out treatment (OT), not undergoing therapy. wore accelerometers for 7 days completed cardiorespiratory fitness,...
This study investigated the effects of 12 wk postexercise kefir consumption in cancer survivors who have undergone chemotherapy and/or radiation therapy.All participants were enrolled a structured exercise training program and separated into (KEF) or control (CON) treatment groups. KEF consumed 8 oz. after sessions (3 d·wk-1) for wk. Outcome measures included assessments body size composition, aerobic fitness muscular strength, medical history, psychological state at pre- postintervention...
Abstract Low protein (LP) diets promote health and longevity in diverse species. Although the precise components of an LP diet that mediate its beneficial effects have not been defined, reducing dietary levels three branched-chain amino acids (BCAAs) leucine, isoleucine valine promotes metabolic both sexes, increases lifespan while frailty male, but female, C57BL/6J mice. Each BCAA has unique effects, we recently showed restriction is sufficient to required for benefits male Here, tested...
Abstract Background: One of the primary risk factors for development diabetes is obesity. Although moderate weight loss can lead to improvements in metabolic health, reduced-calorie diets are difficult sustain. A number groups have shown that low protein associated with health both rodents and humans. In particular, branched-chain amino acids (BCAAs) leucine, isoleucine, valine insulin resistance Blood levels BCAAs decrease humans fed a diet, we recently showed reducing either dietary or...