A5073550038- Genetic diversity and population structure
- Sunflower and Safflower Cultivation
- Genomics and Phylogenetic Studies
- Species Distribution and Climate Change
- Plant and animal studies
- Microbial Community Ecology and Physiology
- Forest Ecology and Biodiversity Studies
- Isotope Analysis in Ecology
- Genetic and Environmental Crop Studies
- Plant Reproductive Biology
- Nitrogen and Sulfur Effects on Brassica
- Environmental DNA in Biodiversity Studies
- Plant Diversity and Evolution
- Cannabis and Cannabinoid Research
- Diet, Metabolism, and Disease
- Ecology and Vegetation Dynamics Studies
- Plant Pathogens and Fungal Diseases
- Pacific and Southeast Asian Studies
- Plant Molecular Biology Research
- Marine Biology and Ecology Research
- Marine and coastal plant biology
- Biological Control of Invasive Species
- Pneumonia and Respiratory Infections
- Pancreatic function and diabetes
- Botany, Ecology, and Taxonomy Studies
Harvard University
2018-2025
University of British Columbia
2011-2025
Canada's Michael Smith Genome Sciences Centre
2025
Sunrise Medical (United States)
2018-2021
Laboratoire des Interactions Plantes Micro-Organismes
2020
Harvard University Press
2019
Centre National de la Recherche Scientifique
2017
Université de Toulouse
2017
A high-quality reference for the sunflower genome (Helianthus annuus L.) and analysis of gene networks involved in flowering time oil metabolism provide a basis nutritional exploitation analyses adaptation to climate change. Nicolas Langlade colleagues report sequence domesticated sunflower, Helianthus L., global crop that can maintain stable yields across wide range environmental conditions. Their comparative insights into evolutionary history Asterids. They also analysed transcriptomic...
Flax (Linum usitatissimum) is an ancient crop that widely cultivated as a source of fiber, oil and medicinally relevant compounds. To accelerate improvement, we performed whole-genome shotgun sequencing the nuclear genome flax. Seven paired-end libraries ranging in size from 300 bp to 10 kb were sequenced using Illumina analyzer. A de novo assembly, comprised exclusively deep-coverage (approximately 94× raw, approximately 69× filtered) short-sequence reads (44-100 bp), produced set scaffolds...
Abstract Natural history collections (NHCs) are the foundation of historical baselines for assessing anthropogenic impacts on biodiversity. Along these lines, online mobilization specimens via digitization—the conversion specimen data into accessible digital content—has greatly expanded use NHC across a diversity disciplines. We broaden current vision digitization (Digitization 1.0)—whereby digitized within NHCs—to include new approaches that rely products rather than physical 2.0)....
Demand for cannabidiol (CBD), the predominant cannabinoid in hemp (Cannabis sativa), has favored cultivars producing unprecedented quantities of CBD. We investigated ancestry a new cultivar and synthase genes relation to inheritance. A nanopore-based assembly anchored high-resolution linkage map provided chromosome-resolved genome CBDRx, potent CBD-type cultivar. measured expression by cDNA sequencing conducted population genetic analysis diverse Cannabis accessions. Quantitative trait locus...
Summary Cytonuclear discordance is commonly observed in phylogenetic studies, yet few studies have tested whether these patterns reflect incomplete lineage sorting or organellar introgression. Here, we used whole‐chloroplast sequence data combination with over 1000 nuclear single‐nucleotide polymorphisms to clarify the extent of cytonuclear wild annual sunflowers ( Helianthus ), and test alternative explanations for such discordance. Our analyses indicate that widespread within this group,...
Populus trichocarpa is an ecologically important tree across western North America. We used a large population sample of 498 accessions over wide geographical area genotyped with 34K SNP array to quantify patterns genetic variation in this species (landscape genomics). present evidence that three processes contribute the observed patterns: (1) introgression from sister P. balsamifera, (2) isolation by distance (IBD), and (3) natural selection. Introgression was detected only at margins...
Abstract Genetic mapping of quantitative traits requires genotypic data for large numbers markers in many individuals. For such studies, the use single nucleotide polymorphism ( SNP ) genotyping arrays still offers most cost‐effective solution. Herein we report on design and performance a array Populus trichocarpa (black cottonwood). This was designed with s pre‐ascertained 34 wild accessions covering species latitudinal range. We adopted candidate gene approach to that resulted selection...
Summary The development of modern crops typically involves both selection and hybridization, but to date most studies have focused on the former. In present study, we explore how processes, their interactions, molded genome cultivated sunflower ( Helianthus annuus ), a globally important oilseed. To identify genes targeted by during domestication improvement sunflower, detect post‐domestication hybridization with wild species, analyzed transcriptome sequences 80 genotypes, including wild,...
Abstract Cannabis has been cultivated for millennia with distinct cultivars providing either fiber and grain or tetrahydrocannabinol. Recent demand cannabidiol rather than tetrahydrocannabinol favored the breeding of admixed extremely high content. Despite several draft genomes, genomic structure cannabinoid synthase loci remained elusive. A genetic map derived from a tetrahydrocannabinol/cannabidiol segregating population complete chromosome assembly high-cannabidiol cultivar together...
Abstract The billions of specimens housed in natural science collections provide a tremendous source under–utilized data that are useful for scientific research, conservation, commerce, and education. Digitization mobilization specimen images promises to greatly accelerate their utilization. While digitization collection has been occurring decades, the vast majority remain un–digitized. If task is be completed near future, innovative, high–throughput approaches needed. To create dataset...
For more than 225 million y, all seed plants were woody trees, shrubs, or vines. Shortly after the origin of angiosperms ∼140 y ago (MYA), Nymphaeales (water lilies) became one first lineages to deviate from their ancestral, habit by losing vascular cambium, meristematic population cells that produces secondary xylem (wood) and phloem. Many genes gene families regulate differentiation tissues also primary phloem, which are produced apical meristems retained in nearly plants. Here, we...
Abstract The Streptanthoid complex, a clade of primarily Streptanthus and Caulanthus species in the Thelypodieae (Brassicaceae) is an emerging model system for ecological evolutionary studies. This complex spans full range California Floristic Province including desert, foothill, mountain environments. ability these related to radiate into dramatically different environments makes them desirable study subject exploring how plant expand their ranges adapt new over time. Ecological studies...
Abstract The genomics of local adaptation is an increasingly active field, providing insights into the forces driving ecological speciation and repeatability evolution. Demography gene flow play important role in determining paths by which parallel evolution occurs genomic signatures adaptation. In annual sunflowers, hybridization between species has repeatedly led to colonization extreme habitats, such as sand dunes. a new case dunes that populations H . petiolaris growing at Great Sand...
Few studies have investigated the causes of evolutionary rate variation among plant nuclear genes, especially in recently diverged species still capable hybridizing wild. The recent advent Next Generation Sequencing (NGS) permits investigation genome wide rates protein evolution and role selection generating maintaining divergence. Here, we use individual whole-transcriptome sequencing (RNAseq) to refine our understanding population genomics wild sunflowers (Helianthus spp.) factors that...
We present a draft genome assembly for the tropical liverwort, Marchantia inflexa, which adds to growing body of genomic resources bryophytes and provides an important perspective on evolution diversification land plants. specifically address questions related sex chromosome evolution, sexual dimorphisms, underpinnings dehydration tolerance. This leveraged recently published M. polymorpha, improve scaffolding annotation, aid in identification sex-linked sequences, quantify patterns sequence...
Gracilariaceae has a worldwide distribution including numerous economically important species. We applied high‐throughput sequencing to obtain organellar genomes (mitochondria and chloroplast) from 10 species of and, combined with published genomes, infer phylogenies compare genome architecture among representing main lineages. obtained similar topologies between chloroplast mitochondrial phylogenies. However, the phylogeny was better resolved full support. In this phylogeny, Melanthalia...
We report the draft genome sequence of Exiguobacterium pavilionensis strain RW-2, isolated from a cold thrombolytic microbialite. The isolate grows at temperatures 4 to 50°C, pH levels 5 11, and in media without added NaCl or KCl with 7% NaCl.
Originally isolated from a pediatric patient with otitis media, Haemophilus influenzae strain 375 (Hi375) has been extensively studied as model system for intracellular invasion of airway epithelial cells and other pathogenesis traits. Here, we report its complete genome sequence methylome.
ABSTRACT Dense genetic maps are critical tools for plant breeders and geneticists. While many have been developed sunflower in the last few decades, most based on low‐throughput technologies include marker numbers hundreds. However, two with reasonably dense coverage of about 5000 9000 single nucleotide polymorphism (SNP) loci each recently produced using high‐throughput genotyping methods. Unfortunately, no mapping population is common between maps, making development a joint map challenge....
ABSTRACT This is the first complete mitochondrial genome sequence for sunflower and any member of Asteraceae , largest plant family, which includes over 23,000 named species. The master circle 300,945-bp long 27 protein-coding sequences, 18 tRNAs, 26S, 5S, 18S rRNAs.
Among closely related taxa, proteins involved in reproduction generally evolve more rapidly than other proteins. Here, we apply a functional and comparative genomics approach to compare divergence across deep phylogenetic array of egg-laying live-bearing vertebrate taxa. We aligned annotated set 4,986 1 : orthologs Anolis carolinensis (green lizard), Danio rerio (zebrafish), Xenopus tropicalis (frog), Gallus gallus (chicken), Mus musculus (mouse) according function using ESTs from available...