Florent Murat
A5047473749- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Wheat and Barley Genetics and Pathology
- Cocoa and Sweet Potato Agronomy
- Plant Taxonomy and Phylogenetics
- Genetic diversity and population structure
- Plant Disease Resistance and Genetics
- Plant Pathogens and Fungal Diseases
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Food Chemistry and Fat Analysis
- Plant Reproductive Biology
- Single-cell and spatial transcriptomics
- Plant Gene Expression Analysis
- Congenital heart defects research
- Plant biochemistry and biosynthesis
- Sperm and Testicular Function
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- MicroRNA in disease regulation
- Neuroinflammation and Neurodegeneration Mechanisms
- Glycosylation and Glycoproteins Research
- Forest ecology and management
- Plant Ecology and Taxonomy Studies
- Legume Nitrogen Fixing Symbiosis
Fish Physiology and Genomics Institute
2022-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2010-2024
DKFZ-ZMBH Alliance
2021-2023
Heidelberg University
2021-2023
Génétique, Diversité, Écophysiologie des Céréales
2009-2018
Institut National de la Recherche Agronomique
2010-2015
Université Clermont Auvergne
2010-2014
Centre de Recherche en Nutrition Humaine d'Auvergne
2010
Eucalypts are the world's most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have made them a global renewable resource of fibre energy. We sequenced assembled >94% 640-megabase genome Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, largest proportion thus far plant genomes. also shows highest diversity genes for specialized metabolites such as terpenes that act chemical defence provide unique...
Zhangjun Fei and colleagues report the draft genome of a Chinese elite watermelon inbred line 97103 resequencing 20 diverse accessions that represent three subspecies Citrullus lunatus. Comparative genome-wide analyses identify extent genetic diversity population structure germplasm. Watermelon, lanatus, is an important cucurbit crop grown throughout world. Here we high-quality sequence east Asia cultivar (2n = 2× 22) containing 23,440 predicted protein-coding genes. genomics analysis...
Xavier Argout and colleagues report the draft genome of Theobroma cacao, tropical crop that is source chocolate. The sequence assembly covers approximately 80% genome. We sequenced assembled an economically important tropical-fruit tree This corresponds to 76% estimated size contains almost all previously described genes, with 82% these genes anchored on 10 T. cacao chromosomes. Analysis this information highlighted specific expansion some gene families during evolution, for example,...
A high-quality reference for the sunflower genome (Helianthus annuus L.) and analysis of gene networks involved in flowering time oil metabolism provide a basis nutritional exploitation analyses adaptation to climate change. Nicolas Langlade colleagues report sequence domesticated sunflower, Helianthus L., global crop that can maintain stable yields across wide range environmental conditions. Their comparative insights into evolutionary history Asterids. They also analysed transcriptomic...
Genome sequences of nine species citrus, including oranges, pummelos and mandarins, reveal pathways domestication provide resources for breeding. Cultivated citrus are selections from, or hybrids of, wild progenitor whose identities contributions to remain controversial. Here we sequence compare genomes—a high-quality reference haploid clementine genome mandarin, pummelo, sweet-orange sour-orange genomes—and show that cultivated types derive from two species. Although represent one species,...
We used a novel approach that incorporated chromosome sorting, next-generation sequencing, array hybridization, and systematic exploitation of conserved synteny with model grasses to assign ~86% the estimated ~32,000 barley (Hordeum vulgare) genes individual arms. Using series bioinformatically constructed genome zippers integrate gene indices rice (Oryza sativa), sorghum (Sorghum bicolor), Brachypodium distachyon in model, we were able assemble 21,766 putative linear order. show (H)...
The draft genome of the moss model, Physcomitrella patens, comprised approximately 2000 unordered scaffolds. In order to enable analyses structure and evolution we generated a chromosome-scale assembly using genetic linkage as well (end) sequencing long DNA fragments. We find that 57% comprises transposable elements (TEs), some which may be actively transposing during life cycle. Unlike in flowering plant genomes, gene- TE-rich regions show an overall even distribution along chromosomes....
Oaks are an important part of our natural and cultural heritage. Not only they ubiquitous in most common landscapes1 but have also supplied human societies with invaluable services, including food shelter, since prehistoric times2. With 450 species spread throughout Asia, Europe America3, oaks constitute a critical global renewable resource. The longevity (several hundred years) probably underlies their emblematic historical importance. Such long-lived sessile organisms must persist the face...
The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological molecular level in mammals1-6, probably owing to evolutionary pressure on males be reproductively successful7. However, evolution of individual spermatogenic cell types across mammals remains largely uncharacterized. Here we report analyses single-nucleus transcriptome data for testes from 11 species that cover three main mammalian lineages (eutherians, marsupials monotremes) birds (the...
The expansion of the neocortex, a hallmark mammalian evolution
Florent Murat1,4, Jian-Hong Xu2,4, Eric Tannier3,4, Michael Abrouk1, Nicolas Guilhot1, Caroline Pont1, Joachim Messing2,5 and Jérôme Salse1,5 INRA, UMR 1095, Laboratoire Génétique, Diversité et Ecophysiologie des Céréales, 63100 Clermont Ferrand, France; The Plant Genome Initiative at Rutgers (PGIR), Waksman Institute of Microbiology, Rutgers, State University New Jersey, Piscataway, Jersey 08854, USA; INRIA Rhône-Alpes, Université de Lyon 1, CNRS UMR5558, Biométrie Biologie Évolutive, 69622...
Abstract Bread wheat (Triticum aestivum) inflorescences, or spikes, are characteristically unbranched and normally bear one spikelet per rachis node. Wheat mutants on which supernumerary spikelets (SSs) develop particularly useful resources for work towards understanding the genetic mechanisms underlying inflorescence architecture and, ultimately, yield components. Here, we report characterization of genetically unrelated leading to identification FRIZZY PANICLE (FZP) gene, encoding a member...
The origin of bread wheat (Triticum aestivum; AABBDD) has been a subject controversy and intense debate in the scientific community over last few decades. In 2015, three articles published New Phytologist discussed hexaploid (AABBDD) from diploid progenitors Triticum urartu (AA), relative Aegilops speltoides (BB) tauschii (DD). Access to new genomic resources since 2013 offered opportunity gain novel insights into paleohistory modern wheat, allowing characterization its at unprecedented...
Abstract The 1.5 Gbp/2C genome of pedunculate oak ( Quercus robur ) has been sequenced. A strategy was established for dealing with the challenges imposed by sequencing such a large, complex and highly heterozygous whole‐genome shotgun WGS approach, without use costly time‐consuming methods, as fosmid or BAC clone‐based hierarchical methods. combined short long reads. Over 49 million reads provided Roche 454 GS ‐ FLX technology were assembled into contigs shorter Illumina sequence from...
Abstract To identify genes involved in phenotypic traits, translational genomics from highly characterized model plants to poorly crop provides a valuable source of markers saturate zone interest as well functionally candidate genes. In this paper, an integrated view the pea genetic map was developed. A series gene were mapped and their best reciprocal homologs identified on M. truncatula, L. japonicus, soybean, poplar pseudomolecules. Based syntenic relationships uncovered between 5460...
Brassicaceae is a family of green plants high scientific and economic interest, including thale cress (Arabidopsis thaliana), cruciferous vegetables (cabbages) rapeseed. We reconstruct an evolutionary framework composed high-resolution ancestral karyotypes using the genomes modern A. thaliana, Arabidopsis lyrata, Capsella rubella, Brassica rapa Thellungiella parvula. The karyotype (Brassicaceae lineages I II) eight protochromosomes 20,037 ordered oriented protogenes. After speciation, it...
Abstract The vertebrate brain emerged more than ~500 million years ago in common evolutionary ancestors. To systematically trace its cellular and molecular origins, we established a spatially resolved cell type atlas of the entire sea lamprey—a jawless species whose phylogenetic position affords reconstruction ancestral traits—based on extensive single-cell RNA-seq situ sequencing data. Comparisons this to neural data from mouse other jawed vertebrates unveiled various shared features that...
Bread wheat derives from a grass ancestor structured in seven protochromosomes followed by paleotetraploidization to reach 12 chromosomes intermediate and neohexaploidization (involving subgenomes A, B D) event that finally shaped the 21 modern chromosomes. Insights into syntenome sequencing conserved orthologous set (COS) genes unravelled differences genomic structure (such as gene conservation diversity) genetical landscape recombination pattern) between ancestral well recent duplicated...
Modern plant genomes are diploidized paleopolyploids. We revisited grass genome paleohistory in response to the diploidization process through a detailed investigation of evolutionary fate duplicated blocks. Ancestrally genes can be conserved, deleted, and shuffled, defining dominant (bias toward duplicate retention) sensitive erosion) chromosomal fragments. propose new deriving from an ancestral karyotype structured seven protochromosomes containing 16,464 protogenes following rules where...
The recent access to a large set of genome sequences, combined with robust evolutionary scenario modern monocot (i.e. grasses) and eudicot rosids) species from their founder ancestors, offered the opportunity gain insights into disease resistance genes (R-genes) plasticity. We unravel in current article (i) R-genes repertoire consisting 7883 for monocots 15758 eudicots, (ii) contrasted conservation 23.8% 6.6% dicots, (iii) minimal ancestral pool 384 150 (iv) general pattern organization...