A5034594856- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Reproductive Biology and Fertility
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- Infectious Aortic and Vascular Conditions
- Organ Donation and Transplantation
- Reconstructive Surgery and Microvascular Techniques
- Molecular Biology Techniques and Applications
- Osteoarthritis Treatment and Mechanisms
- Cardiac and Coronary Surgery Techniques
- Pluripotent Stem Cells Research
- Organ and Tissue Transplantation Research
- RNA Interference and Gene Delivery
- Biomedical Ethics and Regulation
- Infective Endocarditis Diagnosis and Management
- 3D Printing in Biomedical Research
- Pancreatic function and diabetes
- Knee injuries and reconstruction techniques
- Bone Tissue Engineering Materials
- Reproductive Health and Technologies
- Insect Utilization and Effects
- Hematopoietic Stem Cell Transplantation
Clemson University
2015-2024
Medical University of South Carolina
1987-2024
Applied Tissue Technologies (United States)
2019-2024
John Radcliffe Hospital
2020
Wellcome Centre for Integrative Neuroimaging
2020
Harefield Hospital
2020
Johns Hopkins Hospital
2019
Wake Forest University
2019
Georgia Institute of Technology
2007-2014
Cell and Tissue Systems (United States)
2007-2014
A scalable technology using iron oxide nanoparticles and inductive radiofrequency heating rapidly uniformly rewarms vitrified tissues.
Collagens and elastin form the fundamental framework of all tissues organs, their expression post-translational processing are tightly regulated in disease health. Because unique structural composition properties, it is a recognized challenge to access these protein structures within complex tissue microenvironment understand how localized changes modulate We describe new workflow using combination matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) with matrix...
Molecules 616 22.5 Synopsis of Vitrification Compared with Freezing, and the Advantagesof Vitreous Cryopreservation 620 22.5.1 Avoidance Ice 620 22.5.2 Advantages Approach 62122.6 Application to Viable Tissues 621 22.6.1 Corneas 622 22.6.2 Vascular Grafts 622
It is well established that, in multicellular systems, conventional cryopreservation results damaging ice formation, both the cells and surrounding extracellular matrix. As an alternative to cryopreservation, we performed a feasibility study using vitrification (ice-free cryopreservation) cryopreserve tissue-engineered blood vessels. Fresh, frozen, vitrified tissueengineered vessels were compared histological methods, cellular viability, mechanical properties. Cryosubstitution methods used...
Tissue-engineered blood vessels may provide a solution to the lack of suitable for coronary and peripheral vessel bypass grafting. Cyclic strain can be used more physiological environment that result in tissue closely resembles native artery. In this study, cyclic is applied collagen-based, tissue-engineered vascular medium. An increased culture time was allow adhere silastic sleeve eliminate longitudinal compaction. improved strength through collagen content as well some radial Mechanical...
Cold preservation has greatly facilitated the use of cadaveric kidneys for transplantation but damage occurs during episode. It is well established that oxidant production increases cold renal and mitochondria are a key target injury. Our laboratory demonstrated storage cells rat leads to increased mitochondrial superoxide levels electron transport chain damage, addition Mitoquinone (MitoQ) solutions blunted this In order better translate animal studies, inclusion large models necessary...
Advances in regenerative medicine manufacturing continue to be a priority for achieving the full commercial potential of important breakthrough therapies. Equally will establishment distribution chains that support transport live cells and engineered tissues organs resulting from these advanced biomanufacturing processes. The importance well-managed chain products requiring specialized handling procedures was highlighted during COVID-19 pandemic serves as reminder critical role logistics...