A5060755675- Atrial Fibrillation Management and Outcomes
- Angiogenesis and VEGF in Cancer
- Cardiac Fibrosis and Remodeling
- Cancer Research and Treatments
- Protease and Inhibitor Mechanisms
- Petroleum Processing and Analysis
- Atherosclerosis and Cardiovascular Diseases
- Enhanced Oil Recovery Techniques
- Hydraulic Fracturing and Reservoir Analysis
- ATP Synthase and ATPases Research
- Remote-Sensing Image Classification
- Lipoproteins and Cardiovascular Health
- Sirtuins and Resveratrol in Medicine
- Medicinal Plants and Bioactive Compounds
- Global Financial Crisis and Policies
- Environmental Changes in China
- Cardiac Imaging and Diagnostics
- Saffron Plant Research Studies
- Artificial Intelligence in Healthcare
- Face and Expression Recognition
- Heat shock proteins research
- State Capitalism and Financial Governance
- IL-33, ST2, and ILC Pathways
- Infective Endocarditis Diagnosis and Management
- Environmental and Agricultural Sciences
Sinopec (China)
2022-2024
Shangqiu First People's Hospital
2010-2022
Tsinghua University
2004-2019
Peking University First Hospital
2019
Peking University
2019
Protgen (China)
2008-2019
Xi'an Jiaotong University
2014
University of Science and Technology of China
2005
Shandong University
2005
State Key Laboratory of Microbial Technology
2005
Heat shock protein 90-alpha (Hsp90alpha) is an intracellular molecular chaperone. However, it can also be secreted with the underlying regulatory mechanism remaining far from clear. Here we show that Hsp90alpha a C-terminal truncated form and its secretion regulated by EEVD motif via interacting proteins containing tetratricopeptide repeat domains. We demonstrate of determined phosphorylation status at residue Thr-90, kinase A phosphatase 5. further prerequisite for proinvasiveness function...
BACKGROUND Irregular heart rhythms are a primary manifestation of cardiovascular disease, considerably contributing to global morbidity and mortality rates. Moreover, patients with cardiac arrhythmias often experience higher prevalence sleep disorders, anxiety, depression owing various factors. AIM To investigate the epidemiological characteristics psychological factors associated arrhythmia in elderly establish theoretical foundation for its prevention treatment older adults. METHODS A...
The aim of this study was to explore the role IL-6-miR-210 in regulation Tregs function and atrial fibrosis fibrillation (AF). levels interleukin (IL)-6 IL-10 AF patients were detected by using ELISA. Proportions Treg cells fluorescence activated cell sorting analysis patients. expression Foxp3, α-SMA, collagen I III determined western blot. mechanocytes authenticated vimentin immunostaining. miR-210 performed quantitative real-time polymerase chain reaction (qRT-PCR). TargetScan used...
To analyze the role of PD-1/PD-L1 signaling pathway in regulating T cell activation and secretion proinflammatory factors atrial fibrillation.
Abstract Recombinant human endostatin ( MES ), showing potent inhibition on angiogenesis and tumour growth, has great potential as a therapeutic agent for tumours. The aim of this study was to evaluate the biophysical biological characterization PEG ylated recombinant (M 2 ES ). mono‐ by conjugation with methoxy polyethylene glycol aldehyde mPEG ‐ ALD modification site identified digested peptide mapping matrix assisted laser desorption/ionization–time flight–mass spectrometry...
Objective To investigate effects of early administration high-dose rosuvastatin(40 mg) on coronary microvascular function and short-term outcome in patients treated with primary percutaneous intervention (PCI) for acute myocardial infarction(AMI). Methods Ninety-four consequent AMI PCI were divided into rosuvastatin group (50 patients) control (44 group). The infarct-related artery flow epicardium was classified compliance the TIMI criteria. Myocardial perfusion assessed using TMPG....
Objective To study the correlation of coronary heart disease with matrix metalloproteinascs-9 and C-reactive protein in order to provide evidence for treatment. Methods 75 examples patients from October 2005 January 2009 my courtyard treatment was observed based on stable angina acute syndrome. 25 group, 50 syndrome group. At same time, 30 normal healthy person were selected as control The level all tested compared. Results After comparision,we found that group compared ,P ＜0.01, difference...
Objective To study the diagnostic value about plasma brain natriureticpeptide level in chronic heart failure order to provide evidence for obout failure. Methods 56examples with patients from August 2007 March 2009 my courtyard treatment were divided into A group( 28 examples)and B group(28 examples)based on NYHA. 50 normal healthy person exam-ples selected as control C group). The natriuretic peptide of three groups compared and studied. Results After comparative study, we found that group...
Objective To assess the influence of metabolic syndrome(MS)on success rate catheter ablation for treatment atrial fibrillation(AF)in elderly. Methods A retrospective study included a total 221 aged patients with AF who underwent first time.The were divided into two groups: an MS group(n=72)and control group(without MS)(n=149). The group had mean age (67.1±5.2) years; (68.3±5.7) years.Forty-six in and 105 experienced paroxysmal fibrillation.Prognoses groups compared at end...