A5100748137- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- Cancer-related gene regulation
- CRISPR and Genetic Engineering
- MicroRNA in disease regulation
- Genomics and Phylogenetic Studies
- RNA Research and Splicing
- Drug Transport and Resistance Mechanisms
- RNA modifications and cancer
- Kruppel-like factors research
- Water Treatment and Disinfection
- Infant Nutrition and Health
- Water Quality Monitoring Technologies
- Pulsed Power Technology Applications
- Magnetic and Electromagnetic Effects
- Bacterial biofilms and quorum sensing
- dental development and anomalies
- Extracellular vesicles in disease
- Animal Genetics and Reproduction
- Algebraic structures and combinatorial models
- Tryptophan and brain disorders
- Cancer Research and Treatments
- Homotopy and Cohomology in Algebraic Topology
- Speech and dialogue systems
- Cytokine Signaling Pathways and Interactions
Tianjin University of Traditional Chinese Medicine
2025
Xuzhou Medical College
2023
Second People’s Hospital of Huai’an
2023
Chengdu University
2023
Ocean University of China
2019-2023
Tianjin Medical University Cancer Institute and Hospital
2023
National Clinical Research Center for Digestive Diseases
2023
Huaian First People’s Hospital
2023
Nanjing Medical University
2022-2023
Qingdao National Laboratory for Marine Science and Technology
2019-2022
Rediscovered as a potential eukaryotic epigenetic mark, DNA N6-adenine methylation (6mA) varies across species in abundance and its relationships with transcription. Here we characterize AMT1-representing distinct MT-A70 family methyltransferase-in the ciliate Tetrahymena thermophila. AMT1 loss-of-function leads to severe defects growth development. Single Molecule, Real-Time (SMRT) sequencing reveals that is required for bulk of 6mA all symmetric at ApT dinucleotides. The detection...
Recent multimodal large language models (MLLMs) have demonstrated significant potential in open-ended conversation, generating more accurate and personalized responses. However, their abilities to memorize, recall, reason sustained interactions within real-world scenarios remain underexplored. This paper introduces MMRC, a Multi-Modal Real-world Conversation benchmark for evaluating six core of MLLMs: information extraction, multi-turn reasoning, update, image management, memory answer...
Abnormal N6-methyladenosine (m6A) modification caused by m6A regulators is a common characteristic in various tumors. However, little known about the role of regulator AlkB homolog 5 (ALKBH5) triple-negative breast cancer (TNBC). In this study, we analyzed influence ALKBH5 on stemness TNBC and molecular mechanism using bioinformatics analysis vivo animal experiments.
Background The brain development of preterm infants is easily affected by various adverse extrauterine factors and complications, resulting in abnormal neurological cognitive development. Recent studies have found that there a significant correlation between intestinal microbial changes behavior. Nevertheless, the impairment microflora newborn has been rarely elucidated. Aim To analyze differences fecal flora, short chain fatty acids (SCFAs) microbiota-gut-brain axis (MGBA)-related serum...
Abstract Background Ciliated protists are a widely distributed, morphologically diverse, and genetically heterogeneous group of unicellular organisms, usually known for containing two types nuclei: transcribed polyploid macronucleus involved in gene expression silent diploid micronucleus responsible transmission genetic material during sexual reproduction generation the macronucleus. Although studies few species culturable ciliated have revealed highly dynamic nature replicative...
ATP-binding cassette subfamily B (ABCB) has been implicated in various essential functions such as multidrug resistance, auxin transport and heavy metal tolerance animals plants. However, the functions, genomic distribution evolutionary history have not characterized systematically lower eukaryotes. As a lineage of highly specialized unicellular eukaryotes, ciliates extremely diverse features including nuclear dimorphism. To further understand structure this gene family, we investigated ABCB...
In the present study, based on both morphologic and phylogenetic analyses, a new genus, Monourostylopsis n. gen., species, Metaurostylopsis alrasheidi sp. as well combination, antarctica ( Jung et al., 2011 ) comb. (original combination: ), are suggested. The genus is diagnosed mainly by having three or more frontoterminal cirri, midventral complex with pairs single row, one right marginal row two left rows. can be easily separated from morphologically similar genera (vs. rows). Based live...
Thousands of genes are expressed in the testis mice. However, details about their roles during spermatogenesis have not been well-clarified for most genes. The purpose this study was to examine effect Slc26a1 deficiency on mouse and male fertility. -knockout (KO) mice were generated using CRISPR/Cas9 technology C57BL/6J background. We found no obvious differences between -KO -WT fertility tests, testicular weight, sperm concentrations, or morphology. Histological analysis that testes had...
<p>Supplementary Figure 1. HNSCC exerts robust activity of the STAT3/EZH2 and PI3K/AKT signaling axes, which were related to growth drug sensitivity.; Supplementary 2. TCGA RNA-seq datasets analysis.; 3. Sequence STAT3 binding sites in HOTAIR gene promoter.</p>
<p>Supplementary Figure 1. HNSCC exerts robust activity of the STAT3/EZH2 and PI3K/AKT signaling axes, which were related to growth drug sensitivity.; Supplementary 2. TCGA RNA-seq datasets analysis.; 3. Sequence STAT3 binding sites in HOTAIR gene promoter.</p>
Motivated by recent developments of $\infty$-categorical theories related to differential graded (dg for short) Lie algebras, we develop a general framework locally finite $\infty$-$\mathfrak{g}$-modules over dg algebra $\mathfrak{g}$. We show that the category such is almost model in sense Vallette. As homotopy theoretical generalization Loday and Pirashvili's objects tensor linear maps, further study weak Loday-Pirashvili modules consisting $\infty$-morphisms from adjoint module From...