A5100785669- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Bone and Dental Protein Studies
- Retinal Development and Disorders
- dental development and anomalies
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Protist diversity and phylogeny
- Environmental Toxicology and Ecotoxicology
- Trace Elements in Health
- Glycosylation and Glycoproteins Research
- Microbial Community Ecology and Physiology
- Heavy Metal Exposure and Toxicity
- NF-κB Signaling Pathways
- RNA Interference and Gene Delivery
- Connexins and lens biology
- interferon and immune responses
- Methane Hydrates and Related Phenomena
- Retinal and Macular Surgery
- Pancreatic function and diabetes
- Yersinia bacterium, plague, ectoparasites research
- RNA and protein synthesis mechanisms
- Invertebrate Immune Response Mechanisms
- Bone Metabolism and Diseases
- Pharmaceutical and Antibiotic Environmental Impacts
Harbin Medical University
2024-2025
Second Affiliated Hospital of Harbin Medical University
2024-2025
Chinese Academy of Forestry
2016-2024
Research Institute of Forestry
2016-2024
Sichuan Agricultural University
2016-2024
Neijiang Normal University
2018-2024
Ocean University of China
2021-2024
Sun Yat-sen University
2021
Sun Yat-sen University Cancer Center
2021
University of Louisville
2002-2009
It was the aim of this study to determine cellular changes that occur in enamel organ, dental follicle, and surrounding bony crypt rat molar prior during tooth eruption. By use light microscope histochemistry detect cells containing tartrate-resistant acid phosphatase (TRAP), it seen TRAP-positive mononuclear were present follicle onset eruption (e.g., three days postnatal age) then declined number Concurrently, osteoclasts initially large numbers on surface molars (three as progressed....
Species of the ciliate class Heterotrichea Stein, 1859 are a cosmopolitan group unicellular eukaryotic microorganisms, many which have been widely used as models in various fields research such regenerative biology, functional ecology, environmental toxicology, and symbiotic behavior. However, species identification heterotrich family Condylostomatidae, especially most species-rich type genus
Single-tailed peptide-amphiphiles have been shown to form nanofibers in solution and gel after screening of their electrostatic charges, those containing cell-binding motifs are promising as tissue engineering scaffolds. A fibronectin-mimetic peptide sequence was developed, both the primary binding domain RGD synergy PHSRN, which has superior cell adhesion properties over simple sequences fibronectin 2D culture. In order test this a 3D environment future, we designed C16 single-tailed...
Abstract Background The pathogenesis of epilepsy is complex, and current antiepileptic drugs do not effectively control the seizures. Cytoplasmic polyadenylation element-binding protein 3 (CPEB3) regulates neuronal excitability, but its mechanism action in clear. In this paper, we investigated effect CPEB3 on seizures elucidated underlying molecular mechanism. Methods Bioinformatics-based search for genes closely associated with epilepsy. Changes expression cellular localization were...
Abstract Walnut oil is in great demand due to its high nutritional value. However, it easily oxidized and often loses typical flavor. This study focused on the role of microwave pretreatment improving flavor oxidative stability walnut oil, also investigated effects unsaturated fatty acids (oleic, palmitoleic, linoleic, linolenic acids) antioxidant components (tocopherols phytosterols). The results indicate that effective generating pyrazine compounds. ‘roasted’ was present when for 2 min or...
As an environmental and industrial pollutant, cadmium (Cd) can cause a broad spectrum of toxicological effects. Multiple organs, especially the liver, are considerably affected by Cd in both humans animals. We investigated protective effects metallothionein (MT) vitamin E (VE) supplementation on Cd‐induced apoptosis grass carp ( Ctenopharyngodon idellus ) liver. Grass were divided into four groups: control group, + phosphate‐buffered saline (PBS) VE MT group. All fish injected with CdCl 2...
Abstract Immunoperoxidase localization of epidermal growth factor receptors (EGFR) and (EGF) itself was examined in rat first second mandibular molars postnatally from day 0 to 12. The results showed that the dental follicle stained heavily for EGFR 8, declined staining at 9, devoid stain 10 onward. Preosteoblasts osteoblasts alveolar bone also lesser ameloblasts odontoblasts observed. Except occasional isolated cells, stellate reticulum did not stain. Light pulp molar seen onward but until...
A prominent cellular event in tooth eruption is the influx of mononuclear cells (monocytes?) into dental follicle at onset eruption. In mandibular first molar rat, this reaches its peak three days postnatally. Because transforming growth factor‐beta 1 (TGF‐β1) chemotactic for monocytes, we used immunocytochemical methods to determine localization rat during postnatal 1–4 and day 7. The results indicate that TGF‐βl displays both a spatial temporal molar. It present stellate reticulum (SR) on...
The aim of this study was to investigate the influence lipoxygenase-less (LOX-less) barley malt on quality wort and beer, with main focus beer flavour stability. In current study, pilot-scale (1000 L) brewing trials were conducted a control AC Metcalfe LOX-less malt, PolarStar. results clearly indicated that showed less nonenal potential than control, although LOX activities in both malts relatively low. brewed from contained much lower concentrations trans-2-nonenal (T2N) gamma-nonalactone,...
purpose. There is increasing evidence that the complement system may play a significant role in one of leading diseases causing blindness elderly population, age-related macular degeneration. In this study, novel retina for regulatory protein system, CD46, proposed. methods. The retinal pigment epithelium (RPE) was obtained from human donor eyes as well immortalized RPE cell lines (ARPE19). Immunohistochemistry and confocal microscopy were used to immunolocalize CD46 β1 integrin....
To determine the distribution and glutamate-mediated activation of nuclear factor (NF) kappaB members in retina pan-purified retinal ganglion cells (RGCs) to characterize steps signal transduction events that lead NFkappaB activation.Retinal expression patterns RGCs were evaluated for five proteins with aid immunohistochemistry. Retinal explants or treated glutamate without presence NDMA receptor antagonist memantine, calcium chelator EGTA, a specific inhibitor calcium/calmodulin-dependent...
Crustaceans have a more persistent starvation tolerance than mammals, birds, reptiles, and even fish. This study is aimed at assessing the survival strategy regulatory mechanism of crustaceans in response to through an animal model using Eriocheir sinensis . In 42-day experiment, hepatopancreas was found become target organ, which characterized by atrophy thin wall hepatic tubules expansion lumen. During short-term starvation, E. activates lipid glycogen metabolism with dominating....
Islet transplantation is a promising treatment for type 1 diabetes. Recent studies have demonstrated that human islet allografts can restore insulin independence to patients with this disease. As isolation and immunotherapeutic techniques improve, the demand cell-based therapy will dictate need other sources of islets. Pig islets could provide an unlimited supply xenotransplantation shown promise as alternative allografts. However, stresses imposed during decrease viability, leading loss...
The spleen is a separate organ of the teleost, playing an essential role in immune reactions. morphology different from fish species. Little knowledge about structure and blood splenic barrier (BSB) Nile tilapia has been reported. To address this issue, we studied histology BSB healthy tilapia. was observed, then H&E staining, modified Jame's ultrastructural techniques were performed to portion into three subregions analyze location components fibers. Thereafter, vital staining with Trypan...
We have previously shown that transplants of normal rat neonatal RPE cells rescued photoreceptor in retinas Royal College Surgeons (RCS) dystrophic rats for up to one year. In this study, we investigated the rescue effects RCS within first three weeks following transplantation an attempt determine if initiate repair mechanisms, specifically, outer segment (OS) regeneration.Freshly isolated from pigmented Long Evans were transplanted into subretinal space 22-23 day-old using a transscleral...