A5041725081- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- HER2/EGFR in Cancer Research
- Thyroid Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- BRCA gene mutations in cancer
- Cancer Diagnosis and Treatment
- CRISPR and Genetic Engineering
- Global Cancer Incidence and Screening
- Ovarian cancer diagnosis and treatment
- Cancer Treatment and Pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Cancer Risks and Factors
- RNA modifications and cancer
- Metastasis and carcinoma case studies
- Advanced Breast Cancer Therapies
- Cancer-related cognitive impairment studies
- Lymphatic System and Diseases
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- Transplantation: Methods and Outcomes
- Cancer-related gene regulation
Pusan National University Yangsan Hospital
2014-2024
Christiana Care Health System
2020
Sungkyunkwan University
2015-2017
Samsung Medical Center
2015-2017
Novem (Netherlands)
2017
Creative Commons
2017
Ministry of Health and Welfare
2017
Samsung (South Korea)
2017
Korea Health Industry Development Institute
2017
American Society of Clinical Oncology
2017
Purpose: A duodenal stump fistula is one of the most severe complications after gastrectomy for gastric cancer.We aimed to analyze risk factors this problem, and identify methods used its prevention management.Methods: We retrospectively reviewed clinical data 716 consecutive patients who underwent curative with a cancer between 2008 2013.Results: occurred in 16 (2.2%) there were 2 deaths group.Univariate analysis revealed age >60 years (odds ratio [OR], 3.09; 95% confidence interval [CI],...
<b><i>Purpose:</i></b> Quality of sleep (QoS), anxiety, depression, and quality life (QoL) are common issues among breast cancer patients. Prospective longitudinal studies QoS, QoL in patients lacking. The aim this study was to find out whether there is a proper treatment point associated with during early <b><i>Methods:</i></b> We used 4 self-report questionnaires about QoL. QoS measured using the Pittsburgh Sleep Index, anxiety Beck Anxiety...
IntroductionThe aim of our study was to analyze the risk lymphedema (LE) according clinicopathologic factors and investigate serial change in body weight during neoadjuvant anthracycline plus cyclophosphamide followed by taxane its correlation with incidence LE.Patients MethodsWe performed a retrospective 2-center 406 patients who had undergone chemotherapy (NAC) surgery from 2007 2014. The regimen included 4 cycles cyclophosphamide, taxane. We investigated presence degree LE using telephone...
The use of immediate breast reconstruction (IBR) following total mastectomy (TM) has increased markedly in patients with cancer. As the indications for IBR have been broadened and more breast-conserving surgery-eligible are undergoing IBR, comparing oncologic safety between TM only becomes difficult. This study aimed to analyze outcomes via a matched case-control methodology. A retrospective review was conducted identify all who underwent 2008 2014. We excluded neoadjuvant chemotherapy,...
Conditional disease-free survival (CDFS) reflects changes over time. Because traditional (DFS) is estimated from the date of diagnosis, it limited in ability to predict risk recurrence patients who have been disease free. In this study, we determined CDFS breast cancer and prognostic factors for DFS. We retrospectively reviewed clinical data 7587 consecutive underwent curative surgery between January 2004 December 2013 at Samsung Medical Center. Univariate multivariate analyses were...
Luminal A breast cancer has a much better prognosis than other subtypes, with low risk of local or regional recurrence. However, there is controversy around under- versus overtreatment regard to adjuvant treatment node-positive, luminal cancer. The purpose this study was identify whether systemic chemotherapy any benefit in and evaluate feasibility endocrine therapy without group.This retrospective 11,025 patients who were surgically treated for invasive at Samsung Medical Center between...
Purpose The purpose of this study was to determine whether magnetic resonance imaging (MRI) could assess the size ductal carcinoma in situ (DCIS) more accurately compared mammography and ultrasonography using histopathological dimension surgical specimen as reference measurement. Methods This a retrospective review data from our institution database breast cancer. Preoperative contrast-enhanced MRI, were performed detect DCIS 131 patients. greatest dimensions determined by modalities with...
Gonadotropin-releasing hormone (GnRH) agonists have been used with adjuvant chemotherapy to protect ovarian function. However, there are no data on the actual pregnancy rates among young breast cancer patients receiving GnRH and concurrent in Korea. Among who underwent surgery from January 2002 April 2012, premenopausal aged between 20 40 years were included analysis. We retrospectively reviewed clinicopathologic features (e.g., age, obstetric menstruation history), recurrence, survival...
To study the outcomes of adjuvant goserelin combined with tamoxifen (GosTam) compared to chemotherapy followed by (ChemTam) in premenopausal patients early stage, luminal A breast cancer.From 2008 until 2013, data were retrospectively collected for who underwent surgery invasive tumors that ≤2.0 cm, node-negative, strongly positive estrogen and progesterone receptors, HER-2-negative, Ki-67 < 25%. The divided into two groups according regimen, either GosTam or ChemTam. All different regimens...
Purpose: The BRCA1/2 gene is the most well-known and studied associated with hereditary breast cancer. genetic testing widely performed in high-risk patients of cancer Korea. This study aimed to investigate clinicopathological characteristics mutation-positive patients. Methods: clinical data 188 Korean who underwent mutation between March 2015 February 2020 at Pusan National University Yangsan Hospital were retrospectively reviewed. according expression BRCA1 BRCA2 mutations analyzed using...
81 Background: As known, larger tumor size and more extensive lymph node (LN) involvement have been considered an independent factor for poor prognosis of breast cancer. We evaluated if very small may be a worse compared to in sized cancer with LN involvement. Methods: A retrospective analysis was made single center all 1400 patients (below 2cm, T1) involved (N1~N3) without metastasis diagnosed between 2004 2014. Their ages ranged from 23 88 years (mean age 49.1 ± 9.9 years) mean follow-up...
Methyltransferase-like (METTL)18 has histidine methyltransferase activity on the RPL3 protein and is involved in ribosome biosynthesis translation elongations. Several studies have reported that actin polymerization serves as a Src regulator, HSP90 forming polymerized bundles. To understand role of METTL18 breast cancer to demonstrate importance HER-2 negative metastasis, we used biochemical, molecular biological, immunological approaches
Abstract Recently, a SET domain containing 3 (SETD3) was identified as an actin histidine methyltransferase, functioning to control replication and pathogenesis in multiple mouse models for enterovirus infection well the regulation of smooth muscle contractility linked primary dystocia. Here, this study, we report another type METTL18, that regulates metastatic potential breast cancer human. Among methyltransferases, METTL18 highly amplified human cancer. In particular, poor prognosis...
Abstract: Metastasis to breast from ovarian cancer is very rare, and it difficult distinguish the primary secondary one. In our case, a 61-year-old woman presented hospital with complaints of lower abdominal pain distention. Abdominal-pelvic computed tomography (CT) imaging revealed solid cystic tumor numerable ascites in cavity disseminated peritoneal carcinomatosis. To confirm presence metastasis other organs, preoperative studies including chest CT was performed. Chest an enlargement both...
Women from Asian and western countries have vastly different ages of onset breast cancer, with the disease tending to occur at an older age in West. Through investigation patterns old-onset cancer (OBC) Korean women, we aimed identify characteristics OBC evaluate whether these are changing relation increasing westernization.This study retrospectively evaluated 102,379 patients who underwent surgical treatment primary between January 1, 2000 December 31, 2013 Korea. We used hospital -based...
Core needle biopsy (CNB) is a widely used procedure for breast cancer diagnosis and analyzing results of immunohistochemistry (IHC). Several studies have shown concordance or discordance in IHC between CNB surgical specimens (SS). A double-check (CNB SS) inefficient costly to perform on all patients. Therefore, it important determine which patients would benefit from double-check.We collected the medical records who underwent surgery at Pusan National University Yangsan Hospital April 2009...
1Busan National University Yangsan Hospital, Dept of Anaesthesiology & Pain Medicine, Yansgan, Kyoungnam, Korea, Republic of, 2Busan Surgery,
Purpose Larger tumor size and more extensive lymph node (LN) involvement have been considered independent factors for poor prognosis of breast cancer. We evaluated whether smaller may be a factor worse compared with larger in small-sized cancer LN involvement. Methods A retrospective analysis was conducted at single center 1,400 patients (â¤2 cm) involved (N1âN3) who underwent radical surgery, had no distant metastases, were diagnosed between 2004 2014. subdivided their into four...