- Renal Diseases and Glomerulopathies
- Renal Transplantation Outcomes and Treatments
- Vasculitis and related conditions
- Renal and Vascular Pathologies
- COVID-19 Clinical Research Studies
- Chronic Kidney Disease and Diabetes
- SARS-CoV-2 and COVID-19 Research
- Cytomegalovirus and herpesvirus research
- Organ Donation and Transplantation
- Neurological Complications and Syndromes
- Dialysis and Renal Disease Management
- Systemic Lupus Erythematosus Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Autoimmune Bullous Skin Diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Long-Term Effects of COVID-19
- Immune responses and vaccinations
- Sarcoidosis and Beryllium Toxicity Research
- Impact of Technology on Adolescents
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Organ and Tissue Transplantation Research
- Diagnosis and treatment of tuberculosis
- Digital Mental Health Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Palliative Care and End-of-Life Issues
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2016-2025
All India Institute of Medical Sciences Bhubaneswar
2022-2025
Institute of Medical Sciences
2025
KIIT University
2020-2024
Jaypee Institute of Information Technology
2024
Leicester General Hospital
2022
Christie's
2022
Creative Commons
2022
Christian Medical College & Hospital
2021
We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17.1 (secrete IFN-γ, associate with corticosteroid resistance) and PD1+Th17 TGF-β1, implicated in fibrosis), related cytokines peripheral blood of Takayasu arteritis (TAK).We circulating Th1, Th2, Th17, Th17.1, PD1+CD4+ lymphocytes, PD1+Th17, Treg inflammatory (IFN-γ, IL-4, IL-6, IL-17A, IL-23, IL-1β, TNF-α) regulatory (IL-10, TGF-β1) TAK (n = 57; median age 35 (interquartile range 26-45) years; 40 females) a...
This study was carried out to look for diagnostic and prognostic role of neutrophil gelatinase-associated lipocalin (NGAL) in early diabetic nephropathy (DN) type 2 diabetes individuals. NGAL measured both urinary serum sample 144 individuals stratified into three categories based on albumin-creatinine ratio 54 control populations with estimated glomerular filtration rate >60 mL/min/1.73 m2 creatinine <1.2 mg/dl. The (sNGAL), urine (uNGAL), uNGAL/urine were significantly higher than the...
Background: This cross-sectional study analyzed the pulmonary function in children with sickle cell disease (SCD), assessing abnormalities and comparing these a control group of other forms anemia. Materials methodology: was conducted from July 2022 to June 2024 at Kalinga Institute Medical Sciences, Bhubaneswar, Odisha, India, included 126 (63 SCD, 63 anemia) aged between six 18 years. Anthropometric data, clinical history, laboratory parameters were collected, tests (PFTs) performed using...
Background: Focal segmental glomerulosclerosis (FSGS) is a kidney disease with diverse causes, classified as primary, genetic, or secondary. There high recurrence rate of FSGS posttransplant and associated significant risk graft loss, especially in the primary cases. In this descriptive study, we aimed to analyze presentation, treatment response, outcomes recurrent (rFSGS) Indian population. Methodology: retrospective from North tertiary care center, identified 18 cases rFSGS over 12 years....
Takayasu arteritis (TAK) could cause a stroke or transient ischemic attack (TIA) in young individuals due to inflammatory vascular occlusion intracerebral hemorrhage. We compared the clinical presentation, angiographic features, longitudinal patterns of disease activity, medical treatments, and survival 34 TAK patients with stroke/TIA 157 without from single-center retrospective cohort. were older (p = 0.044) greater proportion males 0.022), more frequent vision loss (odds ratio (OR) for vs....
Owing to changing epidemiology and therapeutic practices, a change in the spectrum of renal involvement Type-2 diabetes mellitus (T2DM) has also been noted. The treatment non-diabetic kidney disease (NDKD) differs from diabetic (DKD) reversibility NDKD many cases normal, prompts biopsy for rapid accurate diagnosis. Data are scarce on findings T2DM.In this observational study, we prospectively collected data biopsies patients aged ≥ 18 years with T2DM admitted between 1 August 2005 31 July...
To analyze the risk, causes, and predictors of mortality in Takayasu arteritis (TAK).Survival was assessed a cohort patients with TAK using Kaplan-Meier curves. Age- sex-standardized ratio (SMR = observed: expected deaths) for were calculated by applying age- sex-specific rates local population to calculate deaths. Hazard ratios (HR 95%CI) based on demographic characteristics, presenting features, baseline angiographic involvement, disease activity, number immunosuppressive medications used,...
Tacrolimus (TAC) is the mainstay immunosuppressant for renal transplantation. A narrow therapeutic index, multiple drug interactions, and interindividual variability in pharmacokinetics make it obligatory to monitor levels. The Multidrug resistance gene 1 (MDR1) CYP3A5 polymorphism may blend achieve optimal level. dose as per body weight difficult single out early posttransplantation period. In this study, we aimed analyze melding effect of both polymorphisms elicit depending on combination...
Vaccination-induced SARS-CoV-2 neutralizing antibodies are required for herd immunity. Vaccine availability and poor vaccine response in renal transplant recipients (RTRs) remain a concern. There is no report on the efficacy of Covaxin Covishield vaccines RTRs. We recruited 222 live donors RTRs analyzed serum titer anti-SARS-CoV-2 spike protein antibody by chemiluminescent magnetic microparticle immunoassay. Patients were categorized into three groups: group1 with infection vaccination (n =...
Globally, adolescent mental health problems reportedly manifest more severely in individuals with lower literacy. Mental curriculum interventions using social media have been associated positive implementation outcomes. This study aimed to investigate whether such an intervention significantly improves literacy and is outcome measures.This employed a quasi-experimental design, comparing the before-and-after difference between group (n1=77) control (n1=76). A module was delivered media. Data...
Introduction Vaccination is an effective strategy for preventing SARS-CoV-2 infection and associated mortality. Renal Transplant Recipients (RTRs) are vulnerable to acquiring high mortality due their immunocompromised state. Varying responses the different vaccines, depending on types of vaccines population, have been reported. Vaccines supply also limited. The current study evaluated seroconversion rate after 2 doses either COVAXIN™ or COVISHIELD™ vaccination in RTR. Methods serum...
The present study compares disease characteristics, imaging modalities used, and patterns of treatment in two large cohorts Takayasu arteritis (TAK) from Italy India. Clinic files were retrospectively reviewed to retrieve information about initial choices vascular immunosuppressive therapies. Unpaired t-tests compared means, proportions using Fisher’s exact test or Chi square [Odds ratios (OR) with 95% confidence intervals (95%CI) calculated where appropriate]. comprised 318 patients [Italy...
Antibiotic resistance (ABR) is a global issue that draws the attention of all healthcare experts in veterinary and medical fields. Of various factors, indiscriminate unregulated antibiotic usage animals reared for food production, especially cows buffaloes suffering from mastitis, contribute significantly to rising incidence resistant bacteria. A literature survey reveals spread strains mastitis-causing bacteria, like Staphylococcus aureus Escherichia coli, humans. In addition, residues...
Background. CKD patients are often asymptomatic in the early stages and referred late to nephrologists. Late carry a poor prognosis. There is lack of data on outcomes associated with referral patterns from northern India. Methods. In this observational cohort study, all who visited nephrology OPD institute between Nov 1, 2018, Dec 31, 2020, were classified as (ER) if their first encounter nephrologist occurred more than one year before initiation dialysis education about (from nurse or...
To describe the incidence, risk factors, and outcomes associated with serious infections in patients Takayasu arteritis (TA).
A BSTRACT Background: Basic sanitation and waste management have always remained a central issue in India. The country launched its flagship program – Swachh Bharat Abhiyan (SBA) (Clean India Mission) 2014 to abolish open defecation achieve universal coverage. Objective: This study aimed examine barriers toilet use women’s menstrual hygiene practices relation the availability of toilets among rural residents. Materials Methods: Using cross-sectional design multi-stage sampling method, 120...
Purpose: The purpose of the study was to analyze occurrence severe, typical cytomegalovirus (CMV) retinitis (CMVR) in human immunodeficiency virus (HIV) negative, partially immunosuppressed patients, emphasizing inconsistency clinical presentation CMVR and evaluate role combined anti-CMV therapy management such patients. Materials Methods: This a retrospective, observational, noncomparative case series. We examined treated consecutive HIV-negative adult patients CMVR. Blood-based polymerase...
This paper investigates the impact of 2024 Indian Lok Sabha elections on stock market, a relationship significant interest to economists, investors, and policymakers. Given pivotal role in shaping India's economic policies legislative landscape, outcomes these are expected have substantial implications for market dynamics. Historical data analysis reveals that past consistently led increased volatility activity, reflecting investor sentiment towards political stability policy continuity....
Introduction Lupus nephritis (LN) has a considerable impact on the morbidity and mortality of systemic lupus erythematosus (SLE) patients. Long-term comparative outcome data from Indian subcontinent treatment regimens with cyclophosphamide (CYP) mycophenolate mofetil (MMF) are sparse. We assessed renal patient survival for these patients in terms types induction – CYP or MMF two maintenance therapies azathioprine (AZA). Methods retrospectively analysed outcomes 100 LN patients, 67 treated...