- Vasculitis and related conditions
- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Skin Diseases and Diabetes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Systemic Sclerosis and Related Diseases
- Eosinophilic Disorders and Syndromes
- Sarcoidosis and Beryllium Toxicity Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Renal and Vascular Pathologies
- Immunodeficiency and Autoimmune Disorders
- Atherosclerosis and Cardiovascular Diseases
- Sports Performance and Training
- Inflammasome and immune disorders
- Pregnancy and Medication Impact
- Otitis Media and Relapsing Polychondritis
- Coronary Artery Anomalies
- Dialysis and Renal Disease Management
- Heterotopic Ossification and Related Conditions
- Parathyroid Disorders and Treatments
- Soft tissue tumor case studies
- Potassium and Related Disorders
- Salivary Gland Disorders and Functions
- Muscle and Compartmental Disorders
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2020-2024
We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17.1 (secrete IFN-γ, associate with corticosteroid resistance) and PD1+Th17 TGF-β1, implicated in fibrosis), related cytokines peripheral blood of Takayasu arteritis (TAK).We circulating Th1, Th2, Th17, Th17.1, PD1+CD4+ lymphocytes, PD1+Th17, Treg inflammatory (IFN-γ, IL-4, IL-6, IL-17A, IL-23, IL-1β, TNF-α) regulatory (IL-10, TGF-β1) TAK (n = 57; median age 35 (interquartile range 26-45) years; 40 females) a...
The present study validates the 2022 ACR/European Alliance of Associations for Rheumatology (EULAR) classification criteria Takayasu's arteritis (TAK), compared with 1990 ACR TAK criteria.The fulfilment ACR/EULAR and from four referral centres was assessed extracranial giant cell (EC-GCA) other controls. Sensitivity, specificity, positive predictive value (PPV), negative (NPV), likelihood ratio a test (LR+) or (LR-), area under receiver operating characteristics curve (AUC) were...
Takayasu arteritis (TAK) could cause a stroke or transient ischemic attack (TIA) in young individuals due to inflammatory vascular occlusion intracerebral hemorrhage. We compared the clinical presentation, angiographic features, longitudinal patterns of disease activity, medical treatments, and survival 34 TAK patients with stroke/TIA 157 without from single-center retrospective cohort. were older (p = 0.044) greater proportion males 0.022), more frequent vision loss (odds ratio (OR) for vs....
To analyze the risk, causes, and predictors of mortality in Takayasu arteritis (TAK).Survival was assessed a cohort patients with TAK using Kaplan-Meier curves. Age- sex-standardized ratio (SMR = observed: expected deaths) for were calculated by applying age- sex-specific rates local population to calculate deaths. Hazard ratios (HR 95%CI) based on demographic characteristics, presenting features, baseline angiographic involvement, disease activity, number immunosuppressive medications used,...
The present study compares disease characteristics, imaging modalities used, and patterns of treatment in two large cohorts Takayasu arteritis (TAK) from Italy India. Clinic files were retrospectively reviewed to retrieve information about initial choices vascular immunosuppressive therapies. Unpaired t-tests compared means, proportions using Fisher’s exact test or Chi square [Odds ratios (OR) with 95% confidence intervals (95%CI) calculated where appropriate]. comprised 318 patients [Italy...
Psoriasiform rashes as the first manifestation of anti-MDA5 associated myositis Upendra Rathore, Rathore Department Clinical Immunology, Sanjay Gandhi Postgraduate Institute Medical Sciences, Lucknow https://orcid.org/0000-0003-1658-8155 Search for other works by this author on: Oxford Academic PubMed Google Scholar Saloni Haldule, Haldule Byramjee Jeejeebhoy Government College, Sassoon General Hospitals, Pune, India Latika Gupta Correspondence to: Gupta, Immunology and Rheumatology,...
To describe the incidence, risk factors, and outcomes associated with serious infections in patients Takayasu arteritis (TA).
To compare clinical, demographic, laboratory data, prognostic and treatment characteristics of patients with antisynthetase syndrome (ASSD) treated in two different centers India Brazil.This international, two-center, retro-prospective cohort study which was conducted at tertiary rheumatology (one Brazil one India) between January 2000 to 2020 included a total 115 ASSD (21 males, 94 females; mean age; disease diagnosis 40.3; range, 18 80 years). Demographic, clinical data the were recorded....
Idiopathic inflammatory myopathies (IIMs) form a heterogeneous group of disorders with deficit quality evidence regarding its management. Therefore, we aimed to explore the prevalent treatment practices in MyoCite cohort from India.Drug usage patterns, their predictors, drug retention rates, efficacy, and adverse reactions were analyzed for adults children newly diagnosed IIM (2017-2020) followed prospectively compared real-world data by performing medical records review. GraphPad Prism...
The mechanisms leading to chronic kidney disease (CKD) in patients with idiopathic inflammatory myopathies (IIMs) are poorly understood. We assessed the prevalence of subclinical renal injury IIMs, through elevation biomarker levels tubular and fibrosis (NGAL, KIM1, Activin A, CD163, Cys-c), differences between subtypes effect activity duration.Clinical data, core set measures, sera urine were prospectively collected from all enrolled MyoCite cohort 2017 2021. Twenty healthy subjects (HC) 16...