A5104652259- Vasculitis and related conditions
- Renal Diseases and Glomerulopathies
- Sarcoidosis and Beryllium Toxicity Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Pulmonary Hypertension Research and Treatments
- Renal and Vascular Pathologies
- Congenital Heart Disease Studies
- Systemic Sclerosis and Related Diseases
- Autoimmune and Inflammatory Disorders Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- Rheumatoid Arthritis Research and Therapies
- Breast Cancer Treatment Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Coronary Artery Anomalies
- Vascular anomalies and interventions
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Digital Radiography and Breast Imaging
- Adrenal and Paraganglionic Tumors
- Cancer, Hypoxia, and Metabolism
- Cardiovascular Function and Risk Factors
- Atherosclerosis and Cardiovascular Diseases
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2019-2024
Netaji Subhash Chandra Bose Medical College
2024
Sir Ganga Ram Hospital
2014-2023
Aurobindo Pharma (India)
2021
Louisiana State University Health Sciences Center New Orleans
2021
Sir Ganga Ram Hospital
2020
Stanford Medicine
2016
King Edward Memorial Hospital and Seth G.S. Medical College
2015
We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17.1 (secrete IFN-γ, associate with corticosteroid resistance) and PD1+Th17 TGF-β1, implicated in fibrosis), related cytokines peripheral blood of Takayasu arteritis (TAK).We circulating Th1, Th2, Th17, Th17.1, PD1+CD4+ lymphocytes, PD1+Th17, Treg inflammatory (IFN-γ, IL-4, IL-6, IL-17A, IL-23, IL-1β, TNF-α) regulatory (IL-10, TGF-β1) TAK (n = 57; median age 35 (interquartile range 26-45) years; 40 females) a...
Takayasu arteritis (TAK) could cause a stroke or transient ischemic attack (TIA) in young individuals due to inflammatory vascular occlusion intracerebral hemorrhage. We compared the clinical presentation, angiographic features, longitudinal patterns of disease activity, medical treatments, and survival 34 TAK patients with stroke/TIA 157 without from single-center retrospective cohort. were older (p = 0.044) greater proportion males 0.022), more frequent vision loss (odds ratio (OR) for vs....
To analyze the risk, causes, and predictors of mortality in Takayasu arteritis (TAK).Survival was assessed a cohort patients with TAK using Kaplan-Meier curves. Age- sex-standardized ratio (SMR = observed: expected deaths) for were calculated by applying age- sex-specific rates local population to calculate deaths. Hazard ratios (HR 95%CI) based on demographic characteristics, presenting features, baseline angiographic involvement, disease activity, number immunosuppressive medications used,...
Diagnosing cardiac sarcoidosis (CS) is challenging due to the lack of a sensitive gold standard diagnostic test. Although advanced imaging techniques like magnetic resonance (MRI) (cardiovascular [CMR]) and fluorodeoxyglucose positron emission tomography (FDG-PET) CT are promising, they limited by their availability cost. Two-dimensional speckle-tracking echocardiography (2D-STE) emerging as valuable tool for early detection CS.
The present study compares disease characteristics, imaging modalities used, and patterns of treatment in two large cohorts Takayasu arteritis (TAK) from Italy India. Clinic files were retrospectively reviewed to retrieve information about initial choices vascular immunosuppressive therapies. Unpaired t-tests compared means, proportions using Fisher’s exact test or Chi square [Odds ratios (OR) with 95% confidence intervals (95%CI) calculated where appropriate]. comprised 318 patients [Italy...
To describe the incidence, risk factors, and outcomes associated with serious infections in patients Takayasu arteritis (TA).
To evaluate various types of right ventricular outflow tract obstruction associated with tetralogy Fallot (TOF) emphasis on the abnormality pulmonary arterial system and other cardiovascular anomalies using computed tomography (CT) angiography.We retrospectively evaluated 184 consecutive previously diagnosed TOF patients who underwent CT angiography in our department.Infundibular valvular stenosis was most common type (47.28%) found, followed by isolated infundibular (34.23%). Isolated both...
Xanthogranulomatous pyelonephritis (XGP) is a rare, serious, debilitating illness characterised by an infectious renal phlegmon. Most cases of XGP are unilateral and often associated with urinary tract obstruction, infection, nephrolithiasis, diabetes, and/or immune compromise. This disease process ultimately results in focal or diffuse destruction pathologically lipid-laden foamy macrophages. occurs approximately 1% all infections. The kidney usually non-functional. displays neoplasm like...
The clinical and radiological end points to stop anti-tubercular treatment in central nervous system (CNS) tuberculoma are not known. This retrospective study was done determine find the predictors of poor outcome patients with CNS tuberculoma. Patients who were admitted a diagnosis brain/spine between January 2015 December 2019 completed minimum 1-year follow-up enrolled. Clinical death (modified Rankin scale > 2) analyzed. One hundred eight (male-to-female ratio, 47 [43.5%]:61 [56.5%];...
Assessment of pulmonary vascular dimensions (PVDs) in Tetralogy Fallot (TOF) is an integral part planning transcatheter and surgical interventions. We sought to examine the reliability correlation echocardiography (ECHO) computed tomography angiography (CTA) measurements with those obtained by cardiac catheterization (CCA).Tetralogy physiology patients undergoing ECHO, CTA, CCA within a month prior correction during 2018-2020 were retrospectively enrolled. Indexed diameter annulus (iPAnn),...
Severe hyperkalemia is a life-threatening electrolyte imbalance that may lead to fatal arrhythmias. ECG (electrocardiogram) and serum potassium levels are vital for diagnosing stratifying the risk. Management involves shifting intracellularly eliminating it through renal gastrointestinal routes. Failure diagnose early manage severe requires emergent hemodialysis.
Background: Patients with spondyloarthropathy (SpA) have a higher risk of subclinical atherosclerosis (SCA). We assessed clinical and serological determinants SCA in Indian SpA patients. Methods: (fulfilling ASAS 2010 criteria; n = 104) attending our hospital were recruited; mean carotid intima-media thickness (CIMT) was performed by ultrasonography, along assessment traditional factor evaluation. Microparticles extracted from plasma total, as well endothelial microparticles (EMP), platelet...
<h3>Background:</h3> Takayasu Arteritis (TAK) is a rare large vessel vasculitis requiring long term immunosuppressive therapy. Being chronic disease, it associated with frequent relapses while on or tapering of immunosuppression. We assessed relapses, their predictors, and prognosis in an inception cohort TAK. <h3>Objectives:</h3> 1.To characterize the frequency relapse-free survival. 2.To analyze predictors relapses. 3.To effect mortality. <h3>Methods:</h3> From TAK patients fulfilling 2022...
Abstract Introduction: The aetiologies in unilateral and bilateral adrenal lesions can be different with clinical implications management guidelines, the latter having like hyperplasia, infections, infiltrative neoplasia. Bilateral tumours are more likely to have hereditary/syndromic associations. There is limited data on pathological profile of lesions. Methods: This was a retrospective study where patients were selected from total 266 who presented our institute between January 2016 August...