A5000850485- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Head and Neck Surgical Oncology
- Spinal Fractures and Fixation Techniques
- Neurogenesis and neuroplasticity mechanisms
- Pituitary Gland Disorders and Treatments
- Cerebrospinal fluid and hydrocephalus
- Brain Metastases and Treatment
- Vascular Malformations Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- CNS Lymphoma Diagnosis and Treatment
- Nerve injury and regeneration
- Bone and Joint Diseases
- Spondyloarthritis Studies and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Spinal Cord Injury Research
- Attention Deficit Hyperactivity Disorder
- Epilepsy research and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer therapeutics and mechanisms
- Zebrafish Biomedical Research Applications
- Spinal Dysraphism and Malformations
Chang Gung University
2013-2024
Chang Gung Memorial Hospital
2012-2024
Linkou Chang Gung Memorial Hospital
2016-2024
Keelung Chang Gung Memorial Hospital
2024
Taoyuan Chang Gung Memorial Hospital
2023
Memorial Hospital of South Bend
2019-2020
Weatherford College
2020
Chiayi Chang Gung Memorial Hospital
2016-2018
Chung Shan Medical University Hospital
2017
Chung Shan Medical University
2017
A dural substitute is frequently used to repair dura mater during neurosurgical procedures. Although autologous or commercially available substitutes matched most of the requirements; difficulties repair, including insufficient space for suturing, mechanical strength, easy tear and cerebrospinal fluid leakage, represent major challenges. To meet this need, a photo-crosslinked hydrogel was developed as substitute/anti-adhesion barrier in study, which can show sol-to-gel phase transition situ...
Atypical and malignant meningiomas are rare. Our aim was to examine the treatment outcomes following surgical resection, analyze associations between clinical characteristics overall survival (OS) or relapse free (RFS). 102 patients with atypical underwent microsurgical resection June 2001 November 2009 were analyzed retrospectively. We compared demographics, characteristics, treatment, complications. The five-year ten-year rates 93.5% 83.4%, respectively. Three factors significantly reduced...
Despite intensive medical treatment, patients with glioblastoma (grade IV glioma [GBM]) have a low 5-year survival rate of 5.5%. In this study, the authors tried to improve currently used therapies by identification therapeutic target, IGFBP3, for treatment.
Attention-deficit hyperactivity disorder (ADHD) is associated with higher risk for fracture. Whether the medical treatment ADHD would mitigate remains unclear. In this study, we sought to investigate effect of methylphenidate on fracture, as well moderational role duration in a large national sample. Cases less than 18 years old were identified from Taiwan's National Health Insurance Research Database new primary diagnosis (ICD-9:314) between 1996 and 2013. A total 6201 cases included study...
The incidence and associated mortality of major intraoperative rupture (MIOR) in intracranial aneurysm surgery is diverse. One possible reason that many studies failed to consider properly adjust the factor surgical experience context. We conducted this study clarify role on MIOR outcome. 538 consecutive surgeries performed 501 patients were enrolled study. Various potential predictors evaluated with stratified analysis multivariate logistic regression. impact outcome was further studied a...
<i>Background:</i> Epilepsy is the most common symptom of cavernoma. Although microsurgery mainstay treatment for epileptogenic cavernoma, this procedure may cause severe complications some lesions. This report aimed to study if linear accelerator (LINAC) radiosurgery was an alternative modality <i>Methods:</i> In retrospective study, 29 patients were diagnosed with cavernomas from September 1995 March 2005. Fifteen treated surgical excision and 14 LINAC radiosurgery....
Liver cirrhosis was identified as an independent predictor of poor outcomes in patients suffering trauma and those undergoing major surgeries. The aim this study to report the authors' experiences treating with who undergo brain surgeries.Between 2004 2009, 121 consecutive underwent 144 procedures. Patients were categorized Child-Turcotte-Pugh (referred "Child") Class A, B, or C. patient profiles, including severity cirrhosis, reason for surgery, complications, prognosis factors, analyzed.In...
Abstract Background Spinal cord injury (SCI) and spinal fracture are major complications in patients with ankylosing spondylitis (AS) who sustain trauma. The purpose of this study was to investigate the incidence, predictors, sequelae trauma AS. Methods This retrospective included AS were admitted for between January 1, 2006, June 30, 2016. compared clinical outcomes group 1: SCI alone, 2: alone (no SCI), 3: both fracture. Results Of 6285 during period, only 105 suffered from enrolled study....
OBJECTIVE: Burr hole craniostomy is an effective and simple procedure for treating chronic subdural hematoma (CSDH). However, the surgical outcomes recurrence of CSDH in patients with liver cirrhosis (LC) remain unknown. METHODS: A nationwide population-based cohort study was retrospectively conducted using data from Taiwan National Health Insurance Research Database. The included 29,163 who underwent first-time removal between January 1, 2001, December 31, 2013. In total, 1223 LC 2446...
Introduction. Postoperative delayed hyponatremia is a complication associated with transsphenoidal pituitary surgery. Due to wide spectrum of symptoms, the reported incidence and predictors postoperative vary among studies, this deserves be reviewed systematically. Methods. PubMed, EMBASE, CENTRAL databases were searched until September 1, 2020. Studies included when (1) event number after surgery was reported, or (2) factors such evaluated. Results. A total 27 studies for meta-analysis. The...
To restore lost functions while repairing the neuronal structure after spinal cord injury (SCI), pharmacological interventions with multiple therapeutic agents will be a more effective modality given complex pathophysiology of acute SCI. Toward this end, we prepared electrospun membranes containing aligned core-shell fibers polylactic acid (PLA) shell, and docosahexaenoic (DHA) or brain-derived neurotropic factor (BDNF) in core. The controlled release both pro-regenerative is expected to...
The prognosis and recurrence rate after resection of an anterior skull base lesion via transciliary supraorbital keyhole craniotomy depend on residual tumor volume. extent to which pathology size influence the using this approach is unknown. Sixty-two patients underwent a total 64 operations in retrospective study. Meningioma was most common tumor, followed by pituitary adenoma craniopharyngioma. Age, sex, volume, operative duration, blood loss, complication rates were evaluated. Pre-...
OBJECTIVE Cranioplasty is a relatively simple and less invasive intervention, but it associated with high incidence of postoperative seizures. The of, the risk factors for, such seizures effect prophylactic antiepileptic drugs (AEDs) have not been well studied. authors’ aim was to evaluate that predispose patients postcranioplasty examine role seizure prophylaxis in cranioplasty. METHODS records who had undergone cranioplasty at medical center between 2009 2014 last 2 years follow-up were...
Glioma is the most common and aggressive type of brain tumor. While long non-coding RNAs (lncRNAs) are clearly more abundant in human than protein-coding genes, specific roles lncRNAs mechanisms underlying their dysregulation glioma remain unclear. Here, we focused on that differentially expressed tumor potential biological functions. LOC441204, a novel RNA gene displaying high expression clinical specimens significant upregulation cell lines microarray analyses, was selected for further...