A5100697445- Influenza Virus Research Studies
- Animal Virus Infections Studies
- Virus-based gene therapy research
- interferon and immune responses
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Animal Disease Management and Epidemiology
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- RNA and protein synthesis mechanisms
- Vector-Borne Animal Diseases
- Plant Virus Research Studies
- Gut microbiota and health
- Viral Infections and Vectors
- Bacteriophages and microbial interactions
- Clostridium difficile and Clostridium perfringens research
- RNA modifications and cancer
- Mycobacterium research and diagnosis
- Transgenic Plants and Applications
- Reproductive tract infections research
- RNA regulation and disease
- Toxin Mechanisms and Immunotoxins
- vaccines and immunoinformatics approaches
Shandong Academy of Agricultural Sciences
2015-2025
Poultry Research Institute
2024
Shandong Agricultural University
2004-2017
Harbin Veterinary Research Institute
2009
Chinese Academy of Agricultural Sciences
2009
Pigeons (Columba livia) are usually kept as free-ranging or racing birds, and they have direct contact with livestock, poultry, humans. Therefore, may an important role in the ecology of influenza virus among various species. In present study, we bring together all available sequence data pigeon avian (AIV) from public databases to address current understanding genomic characteristics emergence each subtype AIV pigeons. Collectively, identified 658 strains 21 countries across world, which...
In this study, we determined and analyzed the complete nucleotide sequence of genome a fowl adenovirus isolate SD1356 in China examined its pathogenicity specific pathogen-free chick embryos newly hatched chicks. The full was 44,454 nucleotides length with 58.1% G + C content. Sequence alignment phylogenetic analysis revealed that strain clustered together belonging to serotype 8b adenoviruses E species (FAdV-8b). No regions homologous early E1, E3, E4 mastadenoviruses were recognized, being...
Avian leukosis virus subgroup K (ALV-K) is composed of newly emerging isolates, which cluster separately from the well-characterized subgroups A, B, C, D, E, and J in sequence analysis, exhibits a specific host range unique pattern superinfection interference. ALV-K replicate more slowly avian cells than other ALV strains, leading to escaped detection during eradication, but underlying mechanism are largely unknown. In our previous study, we have reported that JS11C1 most suspected strains...
Newcastle disease virus (NDV) infection leads to disproportion of intestinal tract microbiol population in chickens. Whether vertical NDV affects the formation a healthy and diverse community newly hatched chicks, which might further perturb establishment normal mucosal immunity, is unclear. This study examined effects chick embryos on microbiome chicks at hatch using 16S rRNA genes pyrosequencing. Eleven-day-old specific-pathogen-free chicken eggs were inoculated via intra-allantoic way...
Avian leukosis virus (ALV) continues evolving to obtain new genomic characters enhance its pathogenicity. In the present study, an ALV-J strain LH20180301 was isolated from broiler breeder chickens that reached speak of paralyzation before 20-week-old. The necropsy showed subcutaneous and muscular hemorrhage, developed tumors in multiple organs including bone, liver, spleen, kidney. complete provirus then cloned sequenced investigate molecular characteristics oncogenicity etiology this...
H9N2 subtype avian influenza virus (AIV) is widely prevalent in poultry, and the becoming adaptive to mammals, which poses pandemic importance. Here, BALB/c mice were employed as a model evaluate adaption mammals of 21 field viruses isolated from species between 2016 2019 China. The replication capacity was evaluated lungs mice. pathogenicity compared by weight loss lung lesions infected whole genomic sequences further characterized define associated phenotypes vitro vivo. results showed...
Abstract Background The red-crowned crane is one of the vulnerable bird species. Although captive population has markedly increased over last decade, infectious diseases can lead to death young cranes while few virological studies have been conducted. Methods Using a viral metagenomics approach, we analyzed virome tissues dead with diarrhea symptoms in Dongying Biosphere Reserve, Shandong Province, China and feces individual birds breeding at corresponding center, which were pooled...
N-Linked glycosylation of hemagglutinin (HA) has been demonstrated to regulate the virulence and receptor-binding specificity avian influenza virus (AIV). In this study, we characterized variation trend naturally isolated H9N2 viruses for potential N-linked sites in HA proteins, explored any important role some sites. genes 19 subtype AIV strains since 2001 were sequenced analyzed The results showed that varied by losing one site at residues 200 202, having an additional 295 297 over past...
In recent years, clinical cases of inclusion body hepatitis (IBH) and hydropericardium syndrome (HPS) have been emerging increasing in chicken flocks worldwide. Mixed infections with 2 or more fowl adenovirus (FAdV) serotypes were common these cases. Herein, we collected a sample that was positive for FAdV from 40-day-old broilers IBH HPS symptoms Shandong province China determined the complete genome FAdVs on Illumina HiSeq4000 platform. The results showed contained strains D species C...