- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Dermatologic Treatments and Research
- Animal Disease Management and Epidemiology
- Diagnosis and Treatment of Venous Diseases
- Viral Infections and Immunology Research
- Microbial infections and disease research
- interferon and immune responses
- Influenza Virus Research Studies
- melanin and skin pigmentation
- Thermoregulation and physiological responses
- Skin Protection and Aging
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Plant Virus Research Studies
- Plant and animal studies
- Virology and Viral Diseases
- Crystallization and Solubility Studies
- Advanced oxidation water treatment
- X-ray Diffraction in Crystallography
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Biochemical Analysis and Sensing Techniques
- Constructed Wetlands for Wastewater Treatment
Shandong Academy of Agricultural Sciences
2016-2025
Shenyang Pharmaceutical University
2024-2025
Shandong Normal University
2018-2024
Shandong University
2017-2024
Ministry of Agriculture and Rural Affairs
2024
Wuyi University
2023
Guangdong Academy of Sciences
2023
Shandong Agricultural University
2008-2023
Nanchang University
2023
Second Affiliated Hospital of Nanchang University
2023
ABSTRACT Foot-and-mouth disease virus (FMDV) causes a highly contagious, debilitating in cloven-hoofed animals with devastating economic consequences. To survive the host, FMDV has evolved to antagonize host type I interferon (IFN) response. Previous studies have reported that leader proteinase (L pro ) and 3C of are involved inhibition IFN production. However, whether proteins can inhibit signaling is less well understood. In this study, we first found functioned interfere JAK-STAT pathway....
Abstract Background Honey bee gut microbiota transmitted via social interactions are beneficial to the host health. Although microbial community is relatively stable, individual variations and high strain-level diversity have been detected across honey bees. structure influenced by environmental factors, heritability of members contribution genetics remains elusive. Considering bees within a colony not readily genetically identical due polyandry queen, we hypothesize that can be shaped...
Introduction Early detection of the virus in environment or infected pigs is a critical step to stop African swine fever (ASFV) transmission. The p22 protein encoded by ASFV KP177R gene has been shown have no effect on viral replication and virulence can serve as molecular marker for distinguishing field strains from future candidate deletion vaccine strains. Methods This study established an assay specific highly conserved based recombinase polymerase amplification (RPA) CRISPR/Cas12...
A COF-based multifunctional reusable face mask, which exhibits solar-powered self-sanitizing ability with excellent antibacterial and antiviral performance via a triple-modal synergistic treatment, is reported.
Sepsis is a major cause of mortality in intensive care units (ICUs) and continues to pose significant global health challenge, with sepsis-related deaths contributing substantially the overall burden on healthcare systems worldwide. The primary objective was construct evaluate machine learning (ML) model for forecasting 28-day all-cause among ICU sepsis patients. Data study sourced from eICU Collaborative Research Database (eICU-CRD) (version 2.0). main outcome mortality. Predictor selection...
Abstract In the face of escalating antibiotic resistance crisis, world is embroiled in a silent “antibacterial war”. Scientists are actively searching for innovative antibacterial materials that can be used as effective weapons against bacterial infections. As promising new crystalline porous polymer materials, covalent organic frameworks (COFs) gradually revealing their vast potential applications. This study investigates classification COF‐based agents, provides comprehensive overview...
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is an important pathogen that seriously endangers pig breeding, causing significant economic losses to the global swine industry. Our previous study found DNA sensing innate cGAS-STING signaling pathway plays role in inducing interferon (IFN) upon PRRSV infection inhibition of replication. However, immune evasion its mechanism by still unclear. In current study, we Non-structural protein 5 (Nsp5) strongly inhibits cGAS-STING-IFN...
Goose astrovirus (GAstV), an agent of fatal visceral gout in goslings, has been widely circulating eastern China since 2017, but little is known about its genetic diversity and systematic evolution. In this study, we isolated sequenced nine nearly full-length GAstV genomes conducted comprehensive evolutionary analysis compared them with other reported sequences. Our results indicated that two genotypic species were China, GAstV-2 subgenotype II-c had arisen as the dominant genotype Shandong...
Reflectance confocal microscopy (RCM) images skin at cellular resolution and has shown utility for the diagnosis of nonmelanoma cancer in vivo. It potential to define lesion margins before surgical therapy.To investigate feasibility RCM defining basal cell carcinoma surgery.The 10 lesions were evaluated using RCM. Biopsies used confirm results. A protocol was constructed margins. delineate preoperative 13 patients. Intraoperative frozen biopsy margins.In seven (70.0%) cases, identified suing...
Two floating treatment wetlands (FTWs) in experimental tanks were compared terms of their effectiveness on removing nutrients. The results showed that the FTWs dominated by emergent wetland plants and constructed to remove nutrients from simulated urban stormwater. Iris pseudacorus Thalia dealbata systems effective reducing nutrient. T. higher nutrient removal performance than I. FTWs. Nitrogen (N) phosphorous (P) rates water 3.95 ± 0.19 0.15 0.01 g/m
Abstract PRRS is one of the most important diseases in swine industry. Current inactivated vaccine provides only a limited protection and cannot induce sufficient cell-mediated immune responses. In this study, we first found that mRNA protein levels Th1-type cytokines (IFN-γ, IL-12) Th2-type (IL-6, IL-10) were significantly increased through TRIF/MyD88-NF-κB signaling pathway when porcine peripheral blood monocyte-derived dendritic cells (MoDCs) treated with poly (I: C) TLR3 ligand imiquimod...
Pseudorabies, a highly contagious infectious disease of swine is caused by pseudorabies virus (PRV). PRV can cause fatal infection in other animal species. We report deadly outbreak that killed 87.2% (3522/4028) minks farm 2014 Shandong Province, China. was isolated using Vero cell culture and detected mink samples PCR from died during the outbreak. Epidemiological analysis indicated 5.8% (33/566) were positive to Province. Phylogenetic strains this study same clade with Chinese porcine...
In this study, a bimetallic oxide catalyst of cobalt-manganese (CoMn2O4) was synthesized using the sol-gel method, and it then characterized variety techniques such as scanning electron microscopy (SEM), transmission (TEM), X-ray diffraction (XRD) spectroscopy, photoelectron spectroscopy (XPS), nitrogen adsorption-desorption isotherms. The obtained novel catalyst, i.e., CoMn2O4, used an activator peroxymonosulfate (PMS) for catalytic degradation commonly-used UV filter,...