- Insect and Pesticide Research
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Viral Infectious Diseases and Gene Expression in Insects
- Additive Manufacturing Materials and Processes
- Bee Products Chemical Analysis
- Plant Taxonomy and Phylogenetics
- 3D Printing in Biomedical Research
- bioluminescence and chemiluminescence research
- Plant and Fungal Interactions Research
- Cancer Research and Treatments
- Mobile Health and mHealth Applications
- Insect symbiosis and bacterial influences
- Nanoplatforms for cancer theranostics
- Plant and fungal interactions
- Bartonella species infections research
- High Entropy Alloys Studies
- Botanical Studies and Applications
- Welding Techniques and Residual Stresses
China Agricultural University
2018-2024
Shanghai University of Traditional Chinese Medicine
2021
Central South University
2021
Honeybee gut microbiota plays an important role in host physiology and metabolism. Recent studies have shown that the influence of resident microorganisms regulation honeybee immune system is profound, which protects against pathogen Serratia marcescens. However, only few core members functions been studied. Here, we explored how different bee bacterial species aided clearance pathogenic Hafnia alvei, causes septicemia with a high mortality rate. We found both Gilliamella apicola W8136...
Abstract Nosema ceranae is an intracellular parasite invading the midgut of honeybees, which causes serious nosemosis implicated in honeybee colony losses worldwide. The core gut microbiota involved protecting against parasitism, and genetically engineering native symbionts provides a novel efficient way to fight pathogens. Here, using laboratory-generated bees mono-associated with members, we find that Snodgrassella alvi inhibit microsporidia proliferation, potentially via stimulation host...
Abstract Background Honey bee gut microbiota transmitted via social interactions are beneficial to the host health. Although microbial community is relatively stable, individual variations and high strain-level diversity have been detected across honey bees. structure influenced by environmental factors, heritability of members contribution genetics remains elusive. Considering bees within a colony not readily genetically identical due polyandry queen, we hypothesize that can be shaped...
Abstract Background The spread of antibiotic resistance genes (ARGs) has been global concern as one the greatest environmental threats. gut microbiome animals found to be a large reservoir ARGs, which is also an indicator spectrum. conserved microbiota makes honeybee tractable and confined ecosystem for studying maintenance transfer ARGs across bacteria. Although it that bacteria harbor diverse sets influences variables mechanism driving their distribution remain unclear. Results We...
For the biomedical application of engineered bacteria, strictly regulating function bacteria has always been goal pursued. However, existing regulation methods do not meet needs in vivo bacteria. Therefore, exploration precise is necessary. Herein, heat-sensitive that can respond to thermal stimuli within 30 min were constructed, and control functions was verified intestines various model organisms (including C. elegans, bees, mice). Subsequently, shown colonize mouse tumor microenvironment....
Eusocial pollinators are crucial elements in global agriculture. The honeybees and bumblebees associated with a simple yet host-restricted gut community, which protect the hosts against pathogen infections. Recent genome mining has led to discovery of biosynthesis pathways bioactive natural products mediating microbe-microbe interactions from microbiota. Here, we investigate diversity biosynthetic gene clusters bee microbiota by analyzing 477 genomes cultivated bacteria metagenome-assembled...
Honeybees play a major role in crop pollination, which supports the agricultural economy and international food supply. The colony health of honeybees is threatened by parasitic mite Varroa destructor , inflicts physical injury on hosts serves as vector for variable viruses. Recently, it shows that V . may also transmit bacteria through feeding wound, yet remains unclear whether invading can exhibit pathogenicity to honeybees. Here, we incidentally isolate Enterococcus faecalis one most...
The gut microbiota of honeybees is highly diverse at the strain level and essential to proper function development host. Interactions between host its microbiota, such as specific microbes regulating innate immune system, protect against pathogen infections. However, little known about capacity these strains deposited in one colony inhibit pathogens. In this study, we assembled a defined microbial community based on phylogeny analysis, 'Core-20' community, consisting 20 isolated from...
, a parasite that parasitizes and reproduces in the gut of honeybees, has become serious threat to global apiculture industry. RNA interference (RNAi) technology can be used inhibit
Abstract Background : Honeybee gut microbiota transmitted via social interactions are beneficial to the host health. Although microbial community is relatively stable, individual variations and high strain-level diversity have been detected across honeybees. bee structure influenced by environmental factors, heritability of members contribution genetics remains elusive. Considering bees within a colony not readily genetically identical due polyandry queen, we hypothesize that can be shaped...
Abstract Nosema ceranae is an emergent microsporidia parasite of the European honey bee ( Apis mellifera ), which causes serious nosemosis implicated in honeybee colony losses worldwide. N. obligate intracellular eukaryotic that mainly invades midgut honeybees. Recent studies find gut microbiota potentially involved protecting against parasitism. Here, using laboratory-generated bees mono-associated with members, we Snodgrassella alvi inhibited proliferation, via stimulation host...
Through the literature material law, summary and analysis method, this paper gets result that main problems of physical mental health Chinese college students are increase in number "sedentary less move", fitness test, lack motor skills, diversified even extreme psychological problems. To deal with problems, we use computer big data cloud computing technology to establish a digital management platform for students, so it can cover shortage test functionality, database development alert...
Abstract Honeybee gut microbiota transmitted via social interactions are beneficial to the host health. Although microbial community is relatively stable, individual variations and high strain-level diversity have been detected across honeybees. bee structure influenced by environmental factors, heritability of members contribution genetics remains elusive. Considering bees within a colony not readily genetically identical due polyandry queen, we hypothesize that can be shaped genetics. We...
Abstract Nosema ceranae is an intracellular parasite invading the midgut of honeybees, which causes serious nosemosis implicated in honeybee colony losses worldwide. The core gut microbiota involved protecting against parasitism, and genetic engineering native symbionts provides a novel efficient way to fight pathogens. Here, using laboratory-generated bees mono-associated with members, we find that Snodgrassella alvi inhibited microsporidia proliferation, potentially via stimulation host...
Abstract Eusocial pollinators are crucial elements in global agriculture. The honeybees and bumblebees associated with a simple yet host-restricted gut community, which protect the hosts against pathogen infections. Recent genome mining has led to discovery of biosynthesis pathways bioactive natural products mediating microbe-microbe interactions from microbiota. Here, we investigate diversity novelty biosynthetic gene clusters bee microbiota by analyzing 477 genomes cultivated bacteria...