A5062678380- Genomics and Phylogenetic Studies
- Insect and Arachnid Ecology and Behavior
- Machine Learning in Bioinformatics
- RNA regulation and disease
- Molecular Biology Techniques and Applications
- Animal Behavior and Reproduction
- CRISPR and Genetic Engineering
- Amphibian and Reptile Biology
- Plant and animal studies
- RNA and protein synthesis mechanisms
- Neurobiology and Insect Physiology Research
- Turtle Biology and Conservation
- Genetics, Bioinformatics, and Biomedical Research
- Insect and Pesticide Research
- interferon and immune responses
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Marine Ecology and Invasive Species
- Identification and Quantification in Food
- RNA Research and Splicing
- Genetic diversity and population structure
- Biochemical and Structural Characterization
BGI Group (China)
2020-2025
BGI Research
2024-2025
University of Chinese Academy of Sciences
2023-2025
Huazhong University of Science and Technology
2020
Extensive adenosine-to-inosine (A-to-I) editing of nuclear-transcribed mRNAs is the hallmark metazoan transcriptional regulation. Here, by profiling RNA editomes 22 species that cover major groups Holozoa, we provide substantial evidence supporting A-to-I mRNA as a regulatory innovation originating in last common ancestor extant metazoans. This ancient biochemistry process preserved most phyla and primarily targets endogenous double-stranded (dsRNA) formed evolutionarily young repeats. We...
Abstract Ant colonies with permanent division of labour between castes and highly distinct roles the sexes have been conceptualized to be superorganisms, but cellular molecular mechanisms that mediate caste/sex-specific behavioural specialization remained obscure. Here we characterized brain cell repertoire queens, gynes (virgin queens), workers males Monomorium pharaonis by obtaining 206,367 single-nucleus transcriptomes. In contrast Drosophila , mushroom body Kenyon cells are abundant in...
Ants are ecologically dominant insects in most terrestrial ecosystems, with more than 14,000 extant species about 340 genera recorded to date. However, genomic resources still scarce for species, especially endemic East or Southeast Asia, limiting the study of phylogeny, speciation and adaptation this evolutionarily successful animal lineage. Here, we assemble annotate genomes Odontoponera transversa Camponotus friedae, two ant a natural distribution China, facilitate future evolution.
Abstract Background The agamid dragon lizard Pogona vitticeps is one of the most popular domesticated reptiles to be kept as pets worldwide. capacity breeding in captivity also makes it emerging a model species for range scientific research, especially studies sex chromosome origin and determination mechanisms. Results By leveraging CycloneSEQ DNBSEQ sequencing technologies, we conducted whole genome long-range captive-bred ZZ male construct chromosome-scale reference P. . new ∼1.8 Gb...
Amphibian genomes are usually challenging to assemble due their large genome size and high repeat content. The Limnodynastidae is a family of frogs native Australia, Tasmania New Guinea. As an anuran lineage that successfully diversified on the Australian continent, it represents important in amphibian tree life but lacks reference genomes. Here we sequenced annotated eastern banjo frog
Abstract Extensive adenosine-to-inosine (A-to-I) editing of nuclear-transcribed RNAs is the hallmark metazoan transcriptional regulation, and fundamental to numerous biochemical processes. Here we explore origin evolution this regulatory innovation, by quantifying its prevalence in 22 species that represent all major transitions evolution. We provide substantial evidence extensive RNA emerged common ancestor extant metazoans. find frequency varies across taxa a manner independent complexity....
<title>Abstract</title> Animal behavior is associated with the gene regulatory network (GRN) coordinating expression levels in brain. The eusocial honeybees natural behavioral plasticity provide an ideal model for studying relationship between brain activity and behaviors. Here, using single-nucleus RNA sequencing spatial transcriptomics, we profile changes of 121,247 cells maturation from nursing to foraging outside. We identified 24 subpopulations cells, including Kenyon, glia, optic...
Abstract Amphibian genomes are usually challenging to assemble due large genome size and high repeat content. The Limnodynastidae is a family of frogs native Australia, Tasmania New Guinea. As an anuran lineage that successfully diversified on the Australian continent, it represents important in amphibian tree life but lacks reference genomes. Here we sequenced annotated eastern banjo frog Limnodynastes dumerilii fill this gap. total length assembly 2.38 Gb with scaffold N50 285.9 kb. We...
Repetitive elements in the Limnodynastes dumerilii genome assembly were identified by RepeatMasker, RepeatProteinMask, RepeatModeler and Tandem Repeats Finder.
We first used homology-based and de novo predictions to build gene models for the Limnodynastes dumerilii genome assembly. Then, we searched theLimnodynastes proteins against public databases perform functional annotation.
The raw sequencing data from the 14 libraries (170 bp × 1, 250 500 800 2 kb 3, 5 10 2, and 20 2) were subjected to strict quality control by SOAPnuke (v1.5.3) prior downstream analyses. Briefly, for reads each library, we trimmed unreliable bases at head tail of read where per-position GC content was unbalanced or base low across all reads; removed pairs with adapter contamination, high proportion low-quality unknown (N) bases; duplicate resulted polymerase chain reaction (PCR) amplification...
Repetitive elements in the Limnodynastes dumerilii genome assembly were identified by RepeatMasker, RepeatProteinMask, RepeatModeler and Tandem Repeats Finder.
We first used homology-based and de novo predictions to build gene models for the Limnodynastes dumerilii genome assembly. Then, we searched theLimnodynastes proteins against public databases perform functional annotation.