A5058572541- Genomics and Phylogenetic Studies
- Endometrial and Cervical Cancer Treatments
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Genetic Mapping and Diversity in Plants and Animals
- Cancer Genomics and Diagnostics
- Chromosomal and Genetic Variations
- Agricultural pest management studies
- Management of metastatic bone disease
- Genetic and Environmental Crop Studies
- Ferroptosis and cancer prognosis
- Colorectal Cancer Treatments and Studies
- Photosynthetic Processes and Mechanisms
- Epigenetics and DNA Methylation
- Genetic factors in colorectal cancer
- Marine animal studies overview
- Coral and Marine Ecosystems Studies
- RNA modifications and cancer
- Prostate Cancer Treatment and Research
- Aquaculture disease management and microbiota
- Plant Gene Expression Analysis
- Legume Nitrogen Fixing Symbiosis
- Genetic and phenotypic traits in livestock
- Fish biology, ecology, and behavior
- Plant Virus Research Studies
University of Chinese Academy of Sciences
2021-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025
BGI Research
2023-2025
Peking Union Medical College Hospital
2016-2025
BGI Group (China)
2019-2025
Weifang Medical University
2018-2025
Institute of Vegetables and Flowers
2019-2024
Chinese Academy of Agricultural Sciences
2019-2024
Botswana Geoscience Institute
2024
National Center for Nanoscience and Technology
2022-2023
Asian cultivated rice consists of two subspecies: Oryza sativa subsp. indica and O. japonica Despite the fact that accounts for over 70% total production worldwide is genetically much more diverse, a high-quality reference genome has yet to be published. We conducted map-based sequencing lines, Zhenshan 97 (ZS97) Minghui 63 (MH63), which represent major varietal groups subspecies are parents an elite Chinese hybrid. The sequences were assembled into 237 181 (MH63) contigs, with accuracy...
Abstract Zero hunger and good health could be realized by 2030 through effective conservation, characterization utilization of germplasm resources 1 . So far, few chickpea ( Cicer arietinum ) accessions have been characterized at the genome sequence level 2 Here we present a detailed map variation in 3,171 cultivated 195 wild to provide publicly available for genomics research breeding. We constructed pan-genome describe genomic diversity across its progenitor accessions. A divergence tree...
Abstract Genetic and environmental factors collectively determine plant growth yield. In the past 20 years, genome-wide association studies (GWAS) have been conducted on crops to decipher genetic loci that contribute yield, however, genotype appears be insufficient explain trait variations. Here, we unravel associations between genotypic, phenotypic, rhizoplane microbiota variables of 827 foxtail millet cultivars by an integrated GWAS, microbiome-wide (MWAS) microbiome (mGWAS) method. We...
Antarctic krill (Euphausia superba) is Earth’s most abundant wild animal, and its enormous biomass vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome-level genome, whose large genome size appears have resulted from inter-genic transposable element expansions. Our assembly reveals molecular architecture of circadian clock uncovers expanded gene families associated with molting energy metabolism, providing insights into adaptations cold highly seasonal environment....
As Charles Darwin anticipated, living fossils provide excellent opportunities to study evolutionary questions related extinction, competition, and adaptation. Ginkgo (Ginkgo biloba L.) is one of the oldest plants a fascinating example how people have saved species from extinction assisted its resurgence. By resequencing 545 genomes ginkgo trees sampled 51 populations across world, we identify three refugia in China detect multiple cycles population expansion reduction along with glacial...
Abstract Fruit firmness is a target trait in tomato breeding because it facilitates transportation and storage. However, also complex uncovering the molecular genetic mechanisms controlling fruit has proven challenging. Here, we report map-based cloning functional characterization of qFIRM SKIN 1 ( qFIS1 ), major quantitative locus that partially determines difference compression resistance between cultivated wild accessions. FIS1 encodes GA2-oxidase, its mutation leads to increased...
The infraorder Brachyura (true or short-tailed crabs) represents a successful group of marine invertebrates yet with limited genomic resources. Here we report chromosome-anchored reference genome and transcriptomes the Chinese mitten crab Eriocheir sinensis, catadromous invasive species wide environmental tolerance, strong osmoregulatory capacity high fertility. We show expansion specific gene families in crab, including F-ATPase, which enhances our knowledge on adaptive plasticity this...
Abstract IIn high-refractive-index dielectric nanostructure, the Mie resonance become evident, and destructive interference of radiation fields from electric toroidal dipole moments results in excitation anapole state, which has unique optical properties a dark state can support more diverse phenomena, such as electromagnetically induced transparency (EIT) effect. In this study, we performed numerical simulations composite metamaterial consisting Si nanocubes gold nanorods. The Au-Si...
Abstract Moso bamboo ( Phyllostachys edulis ) is an economically and ecologically important nontimber forestry species. Further development of this species as a sustainable resource has been hindered by lack population genome information. Here, we report moso genomic variation atlas 5.45 million single-nucleotide polymorphisms (SNPs) from whole-genome resequencing 427 individuals covering 15 representative geographic areas. We uncover low genetic diversity, high genotype heterozygosity,...
Abstract Understanding how plants alter their development and architecture in response to ambient temperature is crucial for breeding resilient crops. Here, we identify the quantitative trait locus qMULTIPLE INFLORESCENCE BRANCH 2 ( qMIB2 ), which modulates inflorescence branching high tomato Solanum lycopersicum ). The non-functional mib2 allele may have been selected large-fruited varieties ensure larger more uniform fruits under varying temperatures. MIB2 gene encodes a homolog of...
Abstract Populations and species are threatened by human pressure, but their fate is variable. Some depleted populations, such as that of the northern elephant seal ( Mirounga angustirostris ), recover rapidly even when surviving population was small. The hunted extensively taken collectors between early 1800s 1892, suffering an extreme bottleneck a consequence. Recovery rapid now there over 200,000 individuals. We sequenced 260 modern 8 historical nuclear genomes to assess impact on...
BackgroundJapanese quail (Coturnix japonica), a recently domesticated poultry species, is important not only as an agricultural product, but also model bird species for genetic research. However, most of the biological questions concerning genomics, phylogenetics, and genetics some economic traits have been answered. It thus necessary to complete high-quality genome sequence well series comparative evolution, functional studies.
The Chinese ginseng Panax notoginseng is a domesticated herb with significant medicinal and economic value. Here we report chromosome-level P. genome assembly high (∼79%) repetitive sequence content. juxtaposition the widely distributed, closely related Korean (Panax ginseng) revealed contraction of plant defense genes (in particular R-genes) in genome. We also investigated reasons for larger size species, revealing contributions from two Panax-specific whole-genome duplication events...
Abstract Inflorescence architecture directly impacts yield potential in most crops. As a model of sympodial plants, tomato (Solanum lycopersicum) inflorescence exhibits highly structural plasticity. However, the genetic regulatory network remains unclear. Here, we investigated modulator branching tomato, TARGET OF EAT1 (SlTOE1), an APETALA2 (AP2) family member found to be predominantly expressed floral meristem (FM) tomato. sltoe1 knockout mutants displayed branched inflorescences and...
Background This study aims to investigate the feasibility of fan-beam computed tomography (FBCT)-guided online adaptive radiotherapy (oART) in radical for cervical cancer. Methods Ten patients who underwent cancer were enrolled this study. All received external beam radiation therapy (EBRT) with a prescription dose 50.4 Gy/28f, and daily oART FBCT guidance was performed. Dosimetric analysis conducted on 278 fractions, comparing scheduled plans. The γ passing rate measured through in-vivo...