A5066570277- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Plant Gene Expression Analysis
- Advanced X-ray and CT Imaging
- Sunflower and Safflower Cultivation
- Genetic Mapping and Diversity in Plants and Animals
- Medical Imaging and Analysis
- Plant biochemistry and biosynthesis
- Radiomics and Machine Learning in Medical Imaging
- Digital Radiography and Breast Imaging
- RNA modifications and cancer
- Genetic and phenotypic traits in livestock
- Genetic Associations and Epidemiology
- Horticultural and Viticultural Research
- Genomics and Rare Diseases
- Genetics and Neurodevelopmental Disorders
- Radiation Therapy and Dosimetry
- Wheat and Barley Genetics and Pathology
- Agricultural pest management studies
- Aquaculture disease management and microbiota
- Acute Myeloid Leukemia Research
- Plant Disease Resistance and Genetics
- Physiological and biochemical adaptations
- Molecular Biology Techniques and Applications
Chengdu University of Traditional Chinese Medicine
2015-2025
University of California, San Francisco
2006-2024
Fujian Medical University
2024
National Institute for Parasitic Diseases
2024
Shanghai Jiao Tong University
2012-2024
Dalian Ocean University
2024
Hackensack Meridian Health
2024
Shanghai Children's Medical Center
2006-2023
Kaiser Permanente
2020-2023
Xi'an Railway Survey and Design Institute
2023
Columnaris causes severe mortalities among many different wild and cultured freshwater fish species, but understanding of host resistance is lacking. Catfish, the primary aquaculture species in United States, serves as a great model for analysis against columnaris disease. Channel catfish general highly resistant to disease while blue susceptible. F2 generation hybrids can be produced where phenotypes genotypes are segregating, providing useful system QTL analysis. To identify genes...
Abstract Background Safflower ( Carthamus tinctorius L.) is an important cash crop, of which the dried tube flower not only raw material for dyes and cosmetics but also herb widely used in traditional Chinese medicine. The pigment bioactive compounds are composed flavonoids (mainly quinone chalcones), studies have reported that MeJA can promote biosynthesis chalcones, mechanism underlying effect safflower remains unclear. Here, we attempt to use metabolomics transcriptome technologies...
Safflower is widely used in dying and traditional medicine, C-glucosylquinochalcones are the main metabolic species red color of safflower. Various safflower cultivars have flowers with different colors. However, transcriptional differences among different-colored genes participating C-glucosylquinochalcone biosynthesis largely unknown. To provide insights on this issue, we performed integrated metabolomics transcriptome analyses flavonoid colors (white-W, yellow-Y, light red-LR, deep...
Summary Heat tolerance is a complex and economically important trait for catfish genetic breeding programs. With global climate change, it becoming an increasingly trait. To better understand the molecular basis of heat stress, genome‐wide association study ( GWAS ) was carried out using 250 K SNP array with interspecific backcross progenies, which derived from crossing female channel male F1 hybrid (female × blue catfish). Three significant associated s were detected by performing EMMAX...
The flower of the safflower (Carthamus tinctorius L.) has been widely used in traditional Chinese medicine for ability to improve cerebral blood flow. Flavonoids are primary bioactive components safflower, and their biosynthesis attracted widespread interest. Previous studies mostly second-generation sequencing platforms survey putative flavonoid genes. For a better understanding transcription data genes involved we carry our study.High-quality RNA was extracted from six types tissue. RNAs...
Abstract Saffron, derived from the stigma of Crocus sativus , is not only a valuable traditional Chinese medicine but also expensive spice and dye. Its yield quality are seriously influenced by its flowering transition. However, molecular regulatory mechanism transition in C. still unknown. In this study, we performed morphological, physiological transcriptomic analyses using apical bud samples during floral process. Morphological results indicated that process could be divided into three...
To investigate the association of genetically determined primary open-angle glaucoma (POAG), myopic refractive error (RE), type 2 diabetes (T2D), blood pressure (BP), body mass index (BMI), cigarette smoking, and alcohol consumption with risk age-related cataract.To assess potential causal effects clinical or behavioral factors on cataract risk, we conducted two-sample Mendelian randomization analyses. Genetic instruments, based common genetic variants associated at genome-wide significance...
The aging of seeds seriously affects their yield. Vacuum and low temperatures have been shown to prolong seed life delay senescence. However, the underlying mechanisms that control these processes in safflower yet be explored. Therefore, this study aimed structural, physiological biochemical changes occur stored for one year at different sealing conditions. X-ray imaging, germination percentage determination, determination water content, TTC staining were utilized analyze structure...
BackgroundJapanese quail (Coturnix japonica), a recently domesticated poultry species, is important not only as an agricultural product, but also model bird species for genetic research. However, most of the biological questions concerning genomics, phylogenetics, and genetics some economic traits have been answered. It thus necessary to complete high-quality genome sequence well series comparative evolution, functional studies.
Heterodera schachtii is a well-known cyst nematode that causes serious economic losses in sugar beet production every year. Rapid and visual detection of H. essential for more effective prevention control. In this study, species-specific recombinase polymerase amplification (RPA) primer was designed from specific sequence-characterized amplified region (SCAR) marker. A band obtained reactions with DNA schachtii, but absent nontarget nematodes. The RPA results could be observed by the naked...
Background Safflower ( Carthamus tinctorius L.), well known for its flower, is widely used as a dye and traditional Chinese medicine. Flavonoids, especially flavonoid glycosides, are the main pigments active components. However, their biosynthesis largely unknown. Interestingly, colour of flowers in safflower changed from yellow to red during flower development, while much gene chemical bases transition unclear. Methods In this research, targeted metabolomics transcriptomics were elucidate...
Safflower (Carthamus tinctorius L.) is a multipurpose economic crop that distributed worldwide. Flavonoid glycosides are the main bioactive components in safflower, but only few UDP-glycosyltransferases (UGT) have been identified. Three differentially expressed UGT genes related with accumulation of 9 flavonoid O-glycosides were screened from metabolomics and transcriptome analysis. corolla protoplasts used to confirm glycosylation ability candidates vivo for first time. The astragalin...
While hyperthermia is an effective adjuvant treatment to radiotherapy, we do not completely understand the nature of response heterogeneity.We performed gene expression analysis 22 spontaneous canine sarcomas before and after first administered as radiotherapy. In parallel, diffusion-weighted MRI (DWI) was done prior course at end therapy.From integrative DWI, identified significant correlation between tumor responses with genes involved in VEGF signaling, telomerase, DNA repair,...
Background Safflower ( Carthamus tinctorius L.) is a domesticated species with long history of cultivation and widespread distribution across the globe, light plays an important role in controlling its boundary. Flowers from safflower have been widely used traditional Chinese medicine because their ability to improve cerebral blood flow. Flavonoids are main active compounds many pharmacological effects. In this study, we aimed explore relationship between different intensities flavonoid...
In Europe and the USA combined, over half a million people had hip joint replaced in 2005, contributing to increasing number of radiotherapy patients with metallic prostheses. The treatment plan for external beam radiation therapy is based on delineation anatomy planning CT scan. When implanted objects high atomic (Z) material are present, however, severe image artefacts generated conventional CT, strongly hindering ability delineate some organs. This particularly case prostate short...