A5072745155- Probiotics and Fermented Foods
- Animal Virus Infections Studies
- Influenza Virus Research Studies
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Gut microbiota and health
- Meat and Animal Product Quality
- Respiratory viral infections research
- Virology and Viral Diseases
- Microbial Metabolites in Food Biotechnology
- Viral Infections and Vectors
- Food Quality and Safety Studies
- Virus-based gene therapy research
- Polysaccharides and Plant Cell Walls
- Bacteriophages and microbial interactions
- Inflammasome and immune disorders
- Plant-Microbe Interactions and Immunity
- Genomics and Phylogenetic Studies
- interferon and immune responses
- Enzyme Production and Characterization
- SARS-CoV-2 and COVID-19 Research
- Food Industry and Aquatic Biology
- Lipoproteins and Cardiovascular Health
- Seaweed-derived Bioactive Compounds
- Protein Hydrolysis and Bioactive Peptides
Fudan University
2017-2025
Huashan Hospital
2025
Foshan University
2022-2024
Chengdu University
2024
Texas A&M University
2018-2024
Shenzhen Children's Hospital
2018-2024
Longyan University
1999-2024
Taihe Hospital
2024
Hubei University of Medicine
2024
Hainan Medical University
2020-2022
Here we aimed to explore some vital phenotypes and potential genes involved in probiotic functions adaptive responses of Lactiplantibacillus plantarum DMDL 9010 (LP9010), isolated from Chinese traditional naturally fermented paocai. We found that LP9010 showed good tolerance simulated human gastrointestinal tract, self-coagulation cholesterol-reducing abilities, antioxidant antimicrobial activities. Comparative genomic analysis six L. strains contained 392 unique genes. genome possessed 281...
The lactic acid bacteria (LAB) are a group of Gram-positive, non-respiring, non-spore-forming bacteria, cocci or rods, which produce as the solely main end product carbohydrates fermentation. Some strains LAB probiotics that play important role in food processing and safety, well maintaining human health an integral part microbiota, could be widely found fermented foods, such yogurt, cheese, kimchi, wine. Streptococcus thermophilus, species LAB, exhibits probiotic effects, including...
Summary Fermented vegetables are nutritionally beneficial and promote good health. China possesses abundant raw vegetable materials has a longstanding history of fermented production. However, the traditional process fermentation heavily relies on individual producers' experience knowledge, resulting in inconsistent flavours, variable quality, potential generation harmful substances. The utilisation lactic acid starters can effectively inhibit pathogenic bacteria during process, enhance...
Assembling microscopic metal-organic frameworks into macroscopic polymeric scaffolds to develop highly renewable materials has been a promising yet challenging area of research. Herein, chitosan (CS) blended with nano-cellulose (NC) was unidirectionally transformed an aerogel oriented macropores and then biomineralized zeolite imidazolate frameworks-8 (ZIF-8) form hierarchical structured chitosan-nanocellulose/zeolite (CS-NC-ZIF-8) hybrid aerogel. Incorporating ZIF-8 significantly increases...
To infect an animal host, Salmonella enterica serovar Typhimurium must penetrate the intestinal epithelial barrier. This process of invasion requires a type III secretion system encoded within pathogenicity island I (SPI1). We found that mutant with deletions acetate kinase and phosphotransacetylase genes (ackA-pta) was deficient in SPI1 expression but gene completely restored by supplying medium conditioned growth wild-type strain, suggesting signal produced wild type, not ackA-pta mutant,...
Bacillus coagulans was classified as sporogenic lactic acid bacteria and served a vital potential probiotic. We reported the whole genome sequence of 13002 which assessed for safety probiotic properties based on complete in cooperation with phenotype analysis. The demonstrated single scaffold 3,609781 bp an average guanine cytosine (GC) content 46.86% 3972 protein coding genes. taxonomic status strain established 1352 copy orthologs Clusters Orthologous Groups (COG) annotation predicted...
Abstract SARS-CoV-2 infection is initiated by Spike glycoprotein binding to the human angiotensin-converting enzyme 2 (ACE2) receptor via its domain. Blocking this interaction has been proven be an effective approach inhibit virus infection. Here we report discovery of a neutralizing nanobody named VHH60, which was directly produced from engineering library based on commercialized within very short period. VHH60 competes with ACE2 bind domain protein at S 351 , 470-471 and 493-494 as...
Translation can play a good role as carrier for human communication in different regions, which enables people with types of languages to re-express and exchange ideas according the original content. take one language form adopt another express it, facilitate readers target text understand conveyed by author generate feelings. From perspective medical papers’ abstracts, English translation activities clear understanding development deep progress China, provide reference industry. This paper...
Polysaccharide extracts (0.05 ~ 0.15% w/w) from Lactarius volemus Fr. were used as growth factors and incorporated into three different probiotic yoghurts. Yoghurts with polysaccharide had a significantly improved water‐retention capacity reduced pH ( P < 0.05). also increased the viable count essential amino acid content in yoghurts The best sensory properties achieved addition of 0.10% extracts. Our study suggests that L. are highly efficient factor for shortening fermentation period...
Accumulating evidences have reported that polysaccharide could alleviate colitis through the maintenance of intestinal homeostasis. In this study, an exopolysaccharide (EPS-K4) from Bacillus amyloliquefaciens was obtained via anionic-exchange chromatography which with average molecular weight 10,067 Da and consisted mannose, rhamnose, glucuronic acid, glucose a molar ratio 40.09:23.65:11.42:17.68. Furthermore, administration EPS-K4 relieved symptoms in mice gut microbiota modulation. The...
Previous studies have found that probiotic supplements can ameliorate mental behavioral disorders. This study investigated the effects of Lactiplantibacillus plantarum DMDL 9010 (LP9010) intake on depression-like behavior induced by dextran sodium sulfate (DSS) and its possible mechanism. Male C57BL/6N mice were fed with DSS to establish model ulcerative colitis. LP9010 reduced DSS-induced inflammatory response, repaired intestinal barrier damage, as well lightened behavior. supplementation...
Circular RNAs (circRNAs) have emerged as vital regulators in the development of rheumatoid arthritis (RA). In this study, we aimed to explore functions and mechanisms circ_0001947 RA.The expression circ_0001947, microRNA-671-5p (miR-671-5p) signal transducer activator transcription 3 (STAT3) was determined by quantitative real-time polymerase chain reaction (qRT-PCR) or western blot. Cell Counting Kit-8 (CCK-8) assay, 5'-ethynyl-2'-deoxyuridine (EdU) flow cytometry analysis, transwell assay...
Summary In this study, six groups of carrots were designed and fermented using Weissella paramensenteroides MbWp142 (WP), Levilactobacillus brevis GDMCC 1.773 (LS), Leuconostoc mesenteroides 1.774 (SE), mixed fermentation three lactic acid bacteria (WP + LS SE), pasteurisation group (BG) natural (CK). GC–MS results indicated that inoculation WP SE increased the types contents flavour substances such as alcohols, esters hydrocarbons. Compared with other experimental groups, peak nitrite value...
Summary Paocai, as one of the most widely consumed traditional fermented foods in China, is dominated by lactic acid bacteria (LAB), which exert a significant influence on dynamics metabolites, microecological changes, and sensory quality. In this study, five different paocai groups were designed for fermentation using Lactiplantibacillus plantarum HYY‐DB9 (LP), Levilactobacillus brevis GIM 1.773 (LB), mixture two LABs (LP + LB), pasteurisation (PST), natural (NF). Nitrite content, pH,...