A5016895382- Influenza Virus Research Studies
- Hemophilia Treatment and Research
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Respiratory viral infections research
- Diabetes Management and Research
- Diabetes Treatment and Management
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Hepatitis Viruses Studies and Epidemiology
- Bacterial Infections and Vaccines
- SARS-CoV-2 and COVID-19 Research
- Retinal Imaging and Analysis
- Data-Driven Disease Surveillance
- Health Systems, Economic Evaluations, Quality of Life
- Cancer-related gene regulation
- Cardiovascular Function and Risk Factors
Sanofi (France)
2019-2025
Universität Greifswald
2019-2020
Abstract Background Seasonal influenza epidemics have a substantial public health and economic burden, which can be alleviated through vaccination. The World Health Organization (WHO) recommends 75% vaccination coverage rate (VCR) in: older adults (aged ≥ 65 years), individuals with chronic conditions, pregnant women, children aged 6–24 months healthcare workers. However, no European country achieves this target in all risk groups. In study, potential benefits achieved by reaching VCR was...
Abstract Background Vaccination against seasonal influenza can reduce the duration and severity of symptoms mitigate negative impacts on quality life (QoL). Patient reported outcomes (PROs) provide important data infected individual’s disease course. This study tested Respiratory Infection, Intensity Impact Questionnaire (RiiQTM) PRO, in context community screening programs (CSP), to measure QoL associated with vaccination status, lessons for future implementation.Table 1.Respondent...
Abstract Background Patient-reported outcomes (PRO) and self-swab studies may offer to improve monitoring of infectious diseases. The DANFLU-2 HomeSwab PRO study aimed assess the practicality self-administered swabs digital tracking monitor influenza-like illness (ILI). Methods As part a sub-study trial, participants were instructed self-report ILI quality life (QoL) using Respiratory Intensity Impact Questionnaire (RiiQ) for 14 days following symptom onset. If symptomatic, home-based was...
Abstract Background The lifelong nature of haemophilia makes patient-centred and societal assessments its impact important to clinical policy decisions. Quantifying the humanistic economic burden by severity is key assessing on healthcare systems. We analysed annual direct medical (excluding factor replacement therapy costs) non-medical costs as well health-related quality life (HRQoL) mild, moderate severe disease among adults with A or B without inhibitors in Europe. Participants CHESS II...
Abstract Background Haemophilia bears substantial humanistic and economic burden on children their caregivers. Characterising the differential impact of severe versus moderate paediatric haemophilia is important for clinical health policy decisions. We analysed health-related quality life (HRQoL), annual direct medical (excluding factor treatment costs), non-medical societal costs among adolescents with A or B without inhibitors from European CHESS-PAEDs study. Information was reported by...
Abstract Purpose To assess the comparative efficacy and long-term cost–utility of alternative minimally invasive glaucoma surgeries (MIGSs) when combined with cataract surgery in patients primary open-angle (POAG). Methods Treatment effects, as measured by 1-year reduction intraocular pressure (IOP), were estimated an adjusted indirect treatment comparison. Evidence from randomized clinical trials was identified for four different MIGS methods. A disease-transition model developed capturing...
The objective of this study was to assess the validity Cornerstone Diabetes Simulation (CDS), a Microsoft Excel®-based patient-level simulation for type 2 diabetes mellitus based on risk equations from revised United Kingdom Prospective Study Outcomes Model (UKPDS-OM2, also known as UKPDS 82). Three levels validation were conducted. Internal assessed through independent review and model stress-testing. External addressed by populating CDS with baseline characteristics treatment effects three...
Abstract Background The incidence of certain vaccine-preventative diseases, such as influenza, herpes zoster and pneumococcal infection, continues to be high despite the availability vaccines, resulting in a substantial health economic burden on society, particularly among older adults aged ≥65 years. Methods A cost calculator was developed assess illness disease France. Direct medical costs related diagnosis treatment adult population both inpatient outpatient settings were modelled over...