Comorbidity between depressive and anxiety disorders is common. A hypothesis of the network perspective on psychopathology that comorbidity arises due to interplay symptoms shared by both disorders, with overlapping acting as so-called bridges, funneling symptom activation clusters each disorder. This study investigated this testing whether (i) two mental states "worrying" "feeling irritated" functioned bridges in dynamic state networks individuals depression compared either disorder alone,...

Abstract Recently, there has been renewed interest in the application of assumptions from complex systems theory field psychopathology. One assumption, with high clinical relevance, is that sudden transitions symptoms may be anticipated by rising instability system, which can detected early warning signals (EWS). Empirical studies support idea this principle also applies to The current manuscript discusses whether additionally informative respect specific symptom dimension such a transition...

Abstract Background Intensive longitudinal (IL) designs provide the potential to study symptoms as they evolve in real-time within individuals. This has promising clinical implications, potentially allowing conclusions at level of specific The current aimed establish feasibility IL designs, indicated by self-rated burden and attrition, context psychiatry. Additionally, we evaluated three core assumptions about instruments (diary items) used designs. These are: diary items (1) reflect...

Abstract A prominent hypothesis within the field of psychiatry is that manifestation psychopathology changes from non-specific to specific as illness severity increases. Using a transdiagnostic network approach, we investigated this in four independent groups with increasing severity. We whether symptom domains became more interrelated and formed clusters increased, using empirical tests for two characteristics: global strength modularity-based community detection. Four groups, ranging...

Purpose Police interviewers are typically instructed to prevent eyewitnesses from talking each other, because witnesses can contaminate other's memory. Previous research has not fully examined, however, how discussion between affects correct and incorrect recall of witnessed events. We conducted quantitative qualitative analyses explore the influence co‐witness in more detail. Methods Witnesses were interviewed individually or pairs about a videotaped violent event. individual interviews...

The role of anxiety symptoms in the development functional somatic (FSS) is unknown. Somatic may be triggered by or give rise to symptoms. This study aimed 1) explore interrelationships among within-day worrying, feeling anxious, and symptoms, 2) investigate association between these overall level FSS. included 767 participants (83% females, mean age 39 years), who were recruited through an online crowdsourcing Dutch general population. Somatic, reported thrice daily (6-h intervals) for 30...

Abstract Background As complex dynamic systems approach a transition, their dynamics change. This process, called critical slowing down (CSD), may precede transitions in psychopathology as well. study investigated whether CSD also indicate the direction of future symptom transitions, i.e., they involve an increase or decrease symptoms. Methods In 1, patient with history major depression monitored mental states ten times day for almost eight months. Study 2 used data from TRAILS TRANS-ID...

If psychopathology behaves like a complex dynamic system, sudden onset or worsening of symptoms may be preceded by early-warning signals (EWSs). EWSs could thus reflect personalized warning for impending psychopathology. We empirically investigated this hypothesis in at-risk youths ( N = 122, mean age 23.6 ± 0.7 years, 57% males) from the clinical cohort Tracking Adolescents’ Individual Lives Survey (TRAILS-CC), who provided daily emotion assessments 6 months. analyzed whether (rising...

Altered stress-reactivity may represent a general risk factor for psychopathology. In broad at-risk sample, we examined (a) how stress and mild, daily expressions of psychopathology were interrelated over time, (b) whether could detect subgroups with similar dynamics between (i.e., stress-reactivity), (c) was associated social functioning. One hundred twenty-two young adults (43.4% women, mean age 23.6) at developing wide range completed 6-month diary study. We used group iterative multiple...

This study aimed to explore the associations between cognitions, behaviours and affects fatigue in chronic syndrome/myalgic encephalomyelitis (CFS/ME), their relation reduction of after cognitive behaviour therapy (CBT).In CFS/ME patients, 22 behaviours, cognitions affects, potentially perpetuating were registered 5 times a day using ecological momentary assessment (EMA) an actigraphy. Simultaneous Components Analysis (SCA) was used identify components perpetuation, that tested for with...

Symptoms of psychopathology lie on a continuum ranging from mental health to psychiatric disorders. Although much research has focused progression along this continuum, for most individuals, subthreshold symptoms do not escalate into full-blown This study investigated how the stability psychopathological (attractor strength) varies across severity levels (homebase). Data were retrieved TRAILS TRANS-ID study, where 122 at-risk young adults (mean age 23.6 years old, 57% males) monitored their...

Intensive longitudinal (IL) measurement, which involves prolonged self-monitoring, may have important clinical applications but is also burdening. This raises the question who takes part in and successfully completes IL measurements. preregistered study investigated demographic, personality, economic, social, psychological, or physical participant characteristics are associated with participation compliance an conducted young adults at enhanced risk for psychopathology. Dutch enrolled cohort...

Most studies on the relationship between reward sensitivity and psychopathology have focused one condition at a time not considered potential sex or lifespan differences. Using nonlinear modeling, we explored normative patterns across (age range: 4–91; N = 37,727) for men women, subsequently studied its sex-specific associations with problems (inattention, hyperactivity, autism spectrum, reactive aggression, depression, anxiety, smoking, alcohol, soft hard drug use). Findings indicated trend...

Abstract Introduction Dynamics between symptoms may reveal insights into mechanisms underlying the development of psychosis. We combined a top-down (theory-based) and bottom-up (data-driven) approach to examine which symptom dynamics arise on group-level, subgroup levels, individual levels in early clinical stages. compared data-driven subgroups theory-based subgroups, explored how differed from each other. Methods Data came N = 96 individuals at risk for psychosis divided over four (n1 25,...

Affection and rejection in close relationships during adolescence are thought to impact adult interpersonal functioning, but few studies focused on how the quality of adolescents' with different people (e.g. parents, peers, teachers) impacts daily, micro-level social experiences as well general, macro-level functioning young adulthood. The present study investigated associations between: (i) parental, teacher peer affection (over several months) patterns (i.e. mean, variability inertia)...

There are numerous observations of reward sensitivity being associated with different psychiatric disorders. Nonetheless, most studies investigating this relationship have been cross-sectional. Additionally, current knowledge is fragmentary as often investigate only one disorder at a time. The present study addresses these gaps by whether age 13 predicts the course nine psychopathology domains (attention and hyperactivity, autism spectrum, reactive aggression, proactive mood, anxiety,...

Background There is widespread interest in the general factor of psychopathology or ‘p factor’, which has been proposed to reflect vulnerability psychopathology. We examined what extent this ‘vulnerability’ associated with dysregulations affect and behavior that occur daily life. As such we hoped provide an account how may be maintained. Methods used data from Tracking Adolescents' Individual Lives Survey (TRAILS; N = 2,772) collected at ages 11, 14, 16, 19, 22 years fit a bifactor model...

Introduction Stress is a risk factor for developing psychopathology. Emerging evidence suggests that daily experiences of stress may also predict symptoms during the day. It unclear to what extent influence on psychopathology day same across individuals (including diagnostic boundaries), and which effects are individual-specific Objectives This study aims reveal how interrelated in cross-diagnostic context by modeling individual level temporal networks, examining subgroups with similar...