A5079692493- Herpesvirus Infections and Treatments
- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Retinal Diseases and Treatments
- Pain Mechanisms and Treatments
- Infant Nutrition and Health
- Acne and Rosacea Treatments and Effects
- Spine and Intervertebral Disc Pathology
- Head and Neck Cancer Studies
- Neurological Disease Mechanisms and Treatments
- Retinal and Optic Conditions
- Migraine and Headache Studies
- Hormonal and reproductive studies
- Sleep and related disorders
- Oral microbiology and periodontitis research
- Primary Care and Health Outcomes
- Alzheimer's disease research and treatments
- Electroconvulsive Therapy Studies
- Acute Ischemic Stroke Management
- Neurological Disorders and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Muscle and Compartmental Disorders
- Thermal Regulation in Medicine
- Infant Development and Preterm Care
China Medical University Hospital
2023-2025
China Medical University
2023-2025
China Medical University
2023-2025
Feng Chia University
2024
Importance Combination therapy has emerged as a critical area of interest in managing diabetes; however, the association combination with glucagon-like peptide 1 receptor agonist (GLP-1RA) and thiazolidinedione risk diabetes-related complications remains incompletely understood. Objective To compare hazards cardiovascular-related morbidities mortality among patients type 2 diabetes receiving GLP-1RA plus thiazolidinedione, those monotherapy or nonusers. Design, Setting, Participants This...
Patients with chronic obstructive pulmonary disease (COPD) are susceptible to acute exacerbations, cardiovascular disease, and premature death. To compare the risk of COPD exacerbation, diseases, mortality between sodium-glucose cotransporter-2 (SGLT-2) inhibitor use no in patients type 2 diabetes mellitus (T2DM) COPD. The study included 299,168 diagnosed T2DM National Health Insurance Research Database from January 1, 2009, December 31, 2020. Cox proportional hazards models were used...
Rhabdomyolysis is caused by rapid muscle breakdown. Although patients with mental disorders are more susceptible to rhabdomyolysis, its incidence in this group poorly established. Therefore, we conducted a population-based cohort study investigate and risk group. We retrospective of 120,094 control from the Taiwan National Health Insurance Research Database. excluded rhabdomyolysis diagnosed before index date, which was defined as date first diagnosis disorder beginning antipsychotic...
Inflammatory bowel disease (IBD) is an autoinflammatory which may affect extraintestinal organs, including kidney. However, rare research showed that patients with IBD have higher risk of end-stage renal (ESRD). Furthermore, lack studies compared the potential ESRD and mortality among ulcerative colitis (UC) Crohn (CD). We conducted a nationwide cohort study using National Health Insurance database in Taiwan, from January 2008 to December 2018. A total 3204 diagnosed were enrolled. cases...
This study aimed to evaluate the systemic impact of periodontitis, previously considered a local disease, on cancer occurrence. We enrolled 683,854 participants, comparing incidence among those with and without periodontitis assessing periodontal treatment risk. Regardless gender, age, Charlson comorbidity index, or use non-steroidal anti-inflammatory drugs, patients had lower overall risk than controls. However, men higher prostate (adjusted hazard ratio [aHR] = 1.22; 95% confidence...
Abstract Associations between migraine and retinal vascular occlusion have been reported, but there is no large-scale comprehensive study. Therefore, we aimed to determine risks of in patients with migraine. Using the Taiwan National Health Insurance Research Database from 2009 2020, enrolled 628,760 matched individuals without Study outcomes were diagnoses occlusion, including artery (RAO) vein (RVO). Adjusted hazard ratio (aHR) related was estimated. The cumulative incidences subsequent...
Background: Pulmonary tuberculosis (TB), a global health problem, is typically caused by the bacterium Mycobacterium tuberculosis. Herpes zoster (HZ) reactivation of varicella-zoster virus (VZV). The VZV can be stress. We investigated whether pulmonary TB increases risk HZ development. Methods: This study used data that sampled population 2 million people in 2000 from National Health Insurance Research Database. cohort observed Taiwanese patients aged 20–100 years with to 2017 (tracked...
Background Despite reports on the association between diabetes mellitus (DM) and lumbar disk herniation (LDH), large-scale, nationwide studies exploring this relationship are lacking. We aimed to examine profiles of DM in individuals with LDH explore potential mechanisms underlying development these disorders. Methods This retrospective, population-based study was conducted 2008 2019 using data from National Health Insurance (NHI) research database Taiwan. The primary outcome date initial...
Background Lactation insufficiency is a prevalent challenge for nursing mothers globally. There growing interest in the use of herbal galactagogues enhancing lactation, but their therapeutic efficacy and underlying mechanisms need thorough investigation. This study aims to investigate action addressing lactation by utilizing real-world data employing network analysis approach. Methods Our retrospective used Taiwan’s Longitudinal Health Insurance Database 2000 (LHID2000) identify 490 patients...
This study examines incidence, mortality, medical expenditure and prescription patterns for asthma on a national scale, particularly in Asian countries is limited. Our aim to investigate provide comprehensive overview of healthcare utilization trends from 2009 2018.
Abstract This study aimed to investigate the association between obesity and herpes zoster (HZ) occurrence. used data covering 2 million people in Taiwan 2000, which were obtained from National Health Insurance Research Database. The cohort observed aged 20–100 years with 2000 2017 (tracking 2018). Obesity was indicated by presence of two or more outpatient diagnoses at least one admission record. And, categorized into non-morbid morbid obesity. Patients HZ before index date excluded....
Objective Diseases associated with chronic pain are typically a major source of stress for patients; and have been linked to herpes zoster (HZ) development. Here, we investigated whether obstructive sleep apnea (OSA) is potential stressor that increases the risk HZ postherpetic neuralgia (PHN) in affected individuals.
Recent research has established an association between insomnia and elevated risk of stroke. Given the severe global impact stroke on public health, exploring nonpharmacological interventions, such as acupuncture, that can mitigate among individuals with is crucial. In this retrospective cohort study, we used data from Taiwan National Health Insurance Database (NHIRD) to examine relationship acupuncture who received a diagnosis 2000 2017. The study participants were divided into two cohorts:...
Metabolic dysfunction-associated fatty liver disease (MAFLD) and metabolic steatohepatitis (MASH) pose significant risks for cirrhosis hepatocellular carcinoma (HCC). Daily aspirin statins could reduce HCC in patients with MAFLD/MASH. We aimed to clarify whether combined exert a synergistic effect on prevention of Patients their clinical data were collected from the National Health Insurance Research Database (NHIRD), encompassing about 20 million population. A total 735,574 MAFLD/MASH...
Chronic pancreatitis (CP) may induce systemic inflammation, potentially increasing cancer susceptibility. However, the link between CP and extra-pancreatic remains underexplored. Employing Taiwanese National Health Insurance Database data from 2000 to 2017, we compared 5394 patients with 21,576 non-CP individuals through propensity score matching. exhibited a significantly higher risk (adjusted hazard ratio (aHR) of 1.32 for females 1.68 males) cumulative incidence (p < 0.001)...
Disease-related stress can trigger the occurrence of herpes zoster (HZ). Fatty liver disease (FLD) have adverse effects on human body and may induce in affected individuals. In this study, we investigated whether FLD is associated with an elevated risk HZ.For utilized data from National Health Insurance Research Database, patients 2000 to 2017 were observed (follow-up until 2018). Patients considered if they had at least two outpatient visits or one admission record a diagnostic code FLD....
BACKGROUND Stroke has a significant impact on life expectancy, comparable to that of cardiovascular disease in Asia. We conducted this longitudinal study examine the incidence ischemic stroke and 30-day mortality among persons with without type 2 diabetes (T2D). also compared outcomes between those over under 60 years men women. METHODS enrolled participants from 2000 2018 National Health Insurance Research Database Taiwan. Cox proportional-hazard models were used outcomes. RESULTS The...