A5009323195- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Chronic Kidney Disease and Diabetes
- Chronic Disease Management Strategies
- Dialysis and Renal Disease Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutrition and Health in Aging
- Diet and metabolism studies
- Metabolism, Diabetes, and Cancer
- Health disparities and outcomes
- Diabetes and associated disorders
- Bariatric Surgery and Outcomes
- Diabetes Management and Education
- Acute Ischemic Stroke Management
- Dementia and Cognitive Impairment Research
- Nutritional Studies and Diet
- Intergenerational Family Dynamics and Caregiving
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Hepatitis C virus research
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer, Lipids, and Metabolism
- Body Contouring and Surgery
- ECG Monitoring and Analysis
- Cardiac electrophysiology and arrhythmias
National Health Research Institutes
2016-2025
China Medical University
2015-2025
Min Sheng General Hospital
2015-2025
Ministry of Health and Welfare
2011-2025
National Yang Ming Chiao Tung University
2016-2024
China Medical University
2023
Hungkuang University
2022
Weatherford College
2021
Tainan Municipal Hospital
2020
Fu Jen Catholic University
2020
To determine incidence of dementia in type 2 diabetic (T2DM) patients, and whether there are adverse or favorable effects oral agents (OA) DM, we obtained a representative cohort 800,000 from Taiwan's National Health Insurance database. Thos
No studies have reported the long-term outcomes of initiating sodium-glucose cotransporter-2 inhibitors (SGLT2is) in patients with estimated glomerular filtration rates less than 20 mL/min/1.73 m
The discrepancy of diabetes incidence and care between socioeconomic statuses has seldom been studied concurrently in nations with universal health coverage. We aimed to delineate whether income disparity is associated inequality under a national insurance (NHI) program Asia.From the Taiwan NHI database 2000, representative cohort aged ≥20 years free (n = 600,662) were followed up until 2005. regarded individuals exempt from paying premium as being poor. Adjusted hazard ratios (HRs) used...
Bariatric surgery has been shown to impair bone health. This study aimed investigate the fracture risk in patients after bariatric versus propensity score-matched controls. The authors used National Health Insurance Research Database of Taiwan and identified 2064 who underwent during 2001 2009. These were matched 5027 obese did not receive surgery, using score matching accounting for age, sex, Charlson Comorbidity Index, diabetes, hypertension, hyperlipidemia year morbid obesity was...
Diabetes mellitus (DM) and DM-related complications place a high socioeconomic burden on individuals society. Updating nationwide information periodically is thus pivotal to preventing DM improving its management in Taiwan. We used the National Health Insurance Research Database; disease diagnosis codes were assigned according International Classification of Diseases, 9th Revision, Clinical Modification. was defined as ≥3 outpatient visits or 1 hospitalization within year. excluded with...
Abstract Several previous cross-sectional studies have shown that vegetarians a better metabolic profile than non-vegetarians, suggesting vegetarian dietary pattern may help prevent chronic degenerative diseases. However, longitudinal on the impact of diets traits are scarce. We studied how several sub-types affect traits, including waist circumference, BMI, systolic blood pressure (SBP), diastolic pressure, fasting glucose, total cholesterol (TC), HDL, LDL, TAG and TC:HDL ratio, through...
To develop cut-off points of muscle mass, gait speed and handgrip strength; to examine the prevalence sarcopenia, relationship between sarcopenia stages functional limitations disability by using these points.We pooled individual participant data 2867 community-dwelling older adults from five cohort studies. We defined point a mass index (ASM/ht(2)) as values two standard deviations below sex-specific means young population or 20th percentile distribution in our study population. The...
It has been well recognized that metabolic surgery short-term benefits for mildly obese patients with type 2 diabetes mellitus (T2DM), but how long these effects can be sustained is uncertain.OBJECTIVE To compare the 5-year efficacy between gastrointestinal and medical treatment on glycemic control remission in T2DM body mass index (BMI; calculated as weight kilograms divided by height meters squared) lower than 35. DESIGN, SETTING, AND PARTICIPANTSThis retrospective cohort study compares...
An association between insulin resistance and microalbuminuria in type 2 diabetes has often been found cross-sectional studies. We aimed to reassess this relationship a prospective Taiwanese cohort of diabetic subjects.We enrolled 738 normoalbuminuric subjects, aged 56.6 ± 9.0 years, 2003 2005 followed them through the end 2009. Average follow-up time was 5.2 0.8 years. used urine albumin-to-creatinine ratio define homeostasis model assessment (HOMA-IR) assess resistance. The incidence rate...
Hyperuricemia is the most important risk factor for development of gout; however, not all patients with hyperuricemia develop gout, and experiencing a gout attack are necessarily found to have hyperuricemia. We hypothesized that interactions between serum uric acid (sUA) other potential metabolic comorbidities increase development.A prospective study was conducted link baseline profiles from MJ Health Screening Center outcomes extracted Taiwan National Insurance database. A Cox proportional...
Limited studies have examined the effects of nonsteroidal anti-inflammatory drug (NSAID) use on risk chronic kidney disease (CKD), especially in subjects with hypertension. Using National Health Insurance claims data Taiwan, we conducted a propensity score-matched cohort study to investigate relationship between NSAID and CKD A total 31976 were included this study: not taking any NSAIDs 2007 (n=10782); for 1 89 days (n=10605); ≥90 (n=10589). We performed multivariable proportional hazard...
Importance Diabetic nephropathy and diabetic retinopathy share many similarities in pathophysiological processes. Preclinical studies have shown that sodium-glucose cotransporter 2 inhibitors (SGLT2is) a protective role the risk of retinopathy. Objective To compare sight-threatening associated with SGLT2is other second-line glucose-lowering medications (including pioglitazone, sulfonylureas, dipeptidyl peptidase-4 [DPP-4is]) patients type diabetes (T2D). Design, Setting, Participants This...
Abstract Background This study compared the risks of cardiovascular morbidity and mortality between patients with type 2 diabetes (T2D) without microvascular diseases, matched diseases. Methods We identified newly diagnosed from National Health Insurance Research Database in Taiwan January 1, 2008, to December 31, 2019. Propensity score matching was applied construct pairs diabetic kidney disease, retinopathy, or neuropathy. Multivariable Cox proportional-hazard models were adopted compare...
To confirm whether type 2 diabetes (T2DM) is an affective disorder (AD) precursor, and to establish possible effects of oral anti-hyperglycemic agents (OAAs). A representative cohort 800,000 subjects was obtained from the Taiwanese National Health Insurance database on 1 January 2000. Those with consistent data (n = 762,753) were followed up between 1996 31 December 2007. Over this period, we assessed presence 62,988) or absence 699,795) T2DM, any OAA used 40,232) not 22,756). compare risk...
Pregnancies with large-for-gestational-age (LGA) fetuses are associated increased risks of various adverse perinatal outcomes. While existing research primarily focuses on term neonates, less is known about preterm neonates. This study aims to explore the maternal and neonatal outcomes LGA in neonates different degrees prematurity, compared appropriate-for-gestational-age (AGA) Using Birth Reporting Databases (2007-2018) linked Taiwan's National Health Insurance Research Database, we...
Work occupies a significant portion of adult life, and both cognitive stimulation physical activity have been suggested as factors that may lower dementia risk in later life. To examine the association between mental demands at work dementia. A cohort study. Seven selected districts Taiwan, covering urban rural areas. 4,083 community-dwelling healthy adults aged 55 older from Healthy Aging Longitudinal Study. job matrix conditions by occupation was generated using data representative...
Abstract Background Monitoring and improving intrinsic capacity (IC) well-being are essential for older adults to maintain functional abilities. However, evidence of effective interventions improve IC happiness is scarce. This study examined the effects multicomponent in Healthy Longevity Ageing Place (HOPE) randomised controlled trial on among rural community-dwelling adults. Methods cluster was conducted communities Taiwan (NCT05104034). Participants aged ≥50 were enrolled from September...
Abstract Background Chronic kidney disease and heart allograft vasculopathy are the primary causes of morbidity mortality after cardiac transplant. This study aimed to evaluate impact sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) on transplant survival, cardiovascular events, dialysis, all‐cause in diabetes patients who have undergone transplantation. Methods In this research, we adopted data from TriNetX collaborative network observe outcomes underwent transplants between January 01,...
Background: The National Health Insurance Administration in Taiwan initiated a nationwide pre-end-stage renal disease (ESRD) pay-for-performance (P4P) programme at the end of 2006 to improve quality care for chronic kidney (CKD) patients. This study aimed examine this programme's effect on patients' clinical outcomes and its cost-effectiveness among advanced CKD Methods: We conducted longitudinal observational matched cohort using two population-based datasets. major interests were incidence...
This work presents a fall detection system that is worn on the head, where acceleration and posture are stable such everyday movement can be identified without disturbing wearer. Falling movements recognized by comparing orientation of wearer’s head using prespecified thresholds. The proposed consists triaxial accelerometer, gyroscope, magnetometer; as such, Madgwick’s filter adopted to improve accuracy estimation orientation. Moreover, with its integrated Wi-Fi module, notify an emergency...
AimsThe exact world-wide prevalence of Brugada electrocardiogram (ECG) pattern is still unclear, especially in adults aged 55 years and older. Methods resultsThe study was conducted as part the Healthy Aging Longitudinal Study Taiwan (HALST).Using a stratified random sampled method, sample community-dwelling subjects recruited from seven community-based regions across Taiwan.All enrolled were follow-up annually cause death documented by citizen records.A total 5214 (male/female: 2530/2684)...