A5084054222- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Lipid metabolism and disorders
- Diabetes Treatment and Management
- Cardiac Arrhythmias and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Liver Disease Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Function and Risk Factors
- Traumatic Brain Injury and Neurovascular Disturbances
- Obesity, Physical Activity, Diet
- Chronic Kidney Disease and Diabetes
- Dermatologic Treatments and Research
- Nutritional Studies and Diet
- Cardiac electrophysiology and arrhythmias
- Sleep and related disorders
- Dialysis and Renal Disease Management
- Metabolism, Diabetes, and Cancer
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
- Colorectal Cancer Screening and Detection
- Metabolomics and Mass Spectrometry Studies
National Health Research Institutes
2018-2025
University of Taipei
2023-2025
Songjiang District Central Hospital
2021-2024
National Chung Hsing University
2024
National Yang Ming Chiao Tung University
2024
Guangzhou Institute of Dermatology
2024
North China University of Science and Technology
2024
Office of Disease Prevention
2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2023
Shanghai Innovative Research Center of Traditional Chinese Medicine
2023
No studies have reported the long-term outcomes of initiating sodium-glucose cotransporter-2 inhibitors (SGLT2is) in patients with estimated glomerular filtration rates less than 20 mL/min/1.73 m
Use of low-dose aspirin for the primary prevention cardiovascular events remains controversial because increased risk bleeding may offset overall benefit. Among major events, intracranial hemorrhage is associated with high mortality rates and functional dependency.To assess among individuals without symptomatic disease.PubMed, Embase, Cochrane Central Register Controlled Trials, ClinicalTrials.gov were searched from January 1966 to October 30, 2018.Randomized clinical trials that compared...
The burden of stroke is comparatively greater in Asian countries than the Western world. While there has been a documented recent decline incidence several nations due to better risk factor management, much less known about nature and trajectory Asia over last decade. objective this study was explore factors, medication use, incidence, one-year recurrence Taiwan.We conducted nationwide cohort by reviewing all hospitalized patients (≥ 18 years) with primary diagnosis ischemic between 2001...
This study examined the association of obesity and dyslipidemia according to body measurements among Chinese adults in Shanghai, a place process rapid urbanization. Using baseline data Shanghai Suburban Adult Cohort Biobank (SSACB), subjects completed questionnaires physical examinations, fasting blood was collected for biochemical assays. We estimated odds ratios (OR) 95% confidence interval (CI) by multivariable logistic regression. The prevalence 12.9% 28.8% both general central obesity,...
Abstract Background The impact of triglyceride-glucose (TyG) index, a surrogate marker for insulin resistance, on the risk cardiovascular disease (CVD) in general populations remains controversial. We aimed to comprehensively study relationship between TyG index with incident CVD events population Shanghai. Methods A total 42,651 participants without previous history from Shanghai Suburban Adult Cohort and Biobank (SSACB) were included. SSACB was community-based natural cohort using...
More is to be explored between dietary patterns and sleep quality in the Chinese adult population.
Background and Purpose Additional folic acid (FA) treatment appears to have a neutral effect on reducing vascular risk in countries that mandate FA fortification of food (e.g., USA Canada). However, it is uncertain whether therapy reduces stroke without fortification. The purpose this study was comprehensively evaluate the efficacy prevention Methods PubMed, EMBASE, clinicaltrials.gov from January 1966 August 2016 were searched identify relevant studies. Relative (RR) with 95% confidence...
Abstract Background Studies on the effect of sleep duration cardiovascular health have contradictory findings. Underlying issues may led to inconsistent results and warrant consideration. We aim assess relationship night with incident disease (CVD) in a general population, taking into consideration underlying chronic diseases. Methods Data from Shanghai Suburban Adult Cohort Biobank median follow-up 5.1 years was used, including 33,883 adults aged 20–74 old. Incident CVD cases were reported...
Abstract Background and hypothesis It is unclear if low birth weight (LBW), preterm small for gestational age (SGA) could synergistically cause chronic kidney disease (CKD) end-stage (ESKD). This cohort study was conducted to examine their individual combined impacts on the development of CKD ESKD in childhood. Methods From Taiwan Maternal Child Health Database, we identified 1 477 128 newborns born between January 1, 2009, December 31, 2016. We used a multivariable Cox regression model...
The objective of the present study was to investigate whether pretreatment with single low loading dose tongxinluo (TXL), a traditional Chinese medicine, 1 h before myocardial ischemia could attenuate no-reflow and ischemia-reperfusion injury by regulating endothelial nitric oxide synthase (eNOS) via PKA pathway. In 90-min 3-h reperfusion model, minipigs were randomly assigned following groups: sham, control, TXL (0.05 g/kg, gavaged ischemia), + H-89 (a inhibitor, intravenously infused at...
Background In‐hospital discontinuation of statins has been linked to poorer early stroke outcomes, but the consequences postdischarge or dose reduction statin treatment are unknown. The objective this study was explore effects on recurrent risk. Methods and Results We conducted a nationwide cohort using data from Taiwan National Health Insurance Research Database. Our source population comprised all patients who were prescribed within 90 days discharge after an ischemic between 2001 2012....