A5102766510- Gastrointestinal motility and disorders
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Esophagitis
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Gut microbiota and health
- Lymphoma Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer therapeutics and mechanisms
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Cancer Treatment and Pharmacology
- Hepatitis B Virus Studies
- Peptidase Inhibition and Analysis
- Celiac Disease Research and Management
- Heat shock proteins research
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Dysphagia Assessment and Management
- Gastrointestinal Tumor Research and Treatment
- Stoma care and complications
- Metastasis and carcinoma case studies
Inje University Busan Paik Hospital
2019-2025
Inje University
2020-2024
Pusan National University Hospital
2020
Daewoong Pharmaceutical (South Korea)
2005-2020
Ajou University
2010-2019
Myongji Hospital
2016-2019
Kyungdong Pharmaceutical (South Korea)
2009-2018
Seonam University
2016-2017
Samsung (South Korea)
2016
Inha University
2014
Background/Objectives: The clinical characteristics of colorectal mucosa-associated lymphoid tissue (MALT) lymphoma remain poorly defined, and there is no standardized treatment for the disease. Therefore, we investigated MALT its prognosis based on different modalities. Methods: A retrospective analysis was performed patients diagnosed with from 2003 to 2021 across six hospitals in Korea's Busan-Ulsan-Gyeongnam area. Macroscopic findings classified all cases into polyposis type,...
Few studies have evaluated the use of a smartphone application (app) for educating people undergoing colonoscopy and optimizing bowel preparation. Therefore, this study was designed to develop app as preparation guide evaluate efficacy when used prior colonoscopy.In total, 142 patients (male:female=84:58, mean age=43.5±9.3 years), who were scheduled undergo at Myongji Hospital, enrolled in study. Seventy-one asked that we had recently developed prepare colonoscopy, while 71 sex age-matched...
Owing to the rarity of disease, epidemiologic information on achalasia is limited.This study aimed investigate epidemiology and treatment patterns in population Korea using a national healthcare database.The diagnostic code K22.0 International Classification Diseases was used identify cases between 2007 2011.Treatment modalities for were identified electronic data interchange codes Q7642 or Q7641 balloon dilation QA421 QA422 esophago-cardiomyotomy.A total 3,105 patients with (1,447 men; mean...
Abstract Background Dysbiosis of ulcerative colitis (UC) has been frequently investigated using readily accessible stool samples. However, samples might insufficiently represent the mucosa-associated microbiome status. We hypothesized that luminal contents including loosely adherent bacteria after bowel preparation may be suitable for diagnosing dysbiosis UC. Methods This study included 16 patients with UC (9 men and 7 women, mean age: 52.13 ± 14.09 years) 15 sex- age-matched healthy...
Background. A substantial percentage of patients with ulcerative colitis (UC) have irritable bowel syndrome- (IBS-) like symptoms despite adequate treatment and endoscopic remission. In this study, we evaluated the clinical efficacy probiotic therapy for residual IBS-like in UC Methods. We conducted a multicenter, observational study between April 2018 December 2020 across two university hospitals Korea. Patients whose persisted during remission were included study. Endoscopic was defined as...
Fecal microbiota transplantation (FMT) is a promising therapy for inducing and maintaining remission in patients with ulcerative colitis (UC). However, FMT has not been approved UC treatment Korea. Our study aimed to investigate patient perceptions of under the national medical policy.
Background/Aims Liver biopsy is a standard method for diagnosis of liver cirrhosis in patients with chronic hepatitis. Because an invasive method, non-invasive methods have been used compensated The current study was designed to evaluate the usefulness ultrasonography and routine blood tests viral Methods Two hundred three hepatitis who underwent were included this analyzed retrospectively. Ultrasonographic findings, including surface nodularity, parenchyma echogenecity, spleen size,...
Duodenal immune alterations have been reported in a subset of patients with functional dyspepsia (FD). The aim this study was to investigate the effect acute stress on cell counts and expression tight junction proteins duodenal mucosa.Twenty-one male rats were divided into following three experimental groups: 1) nonstressed, control group, 2) 2-hour-stressed 3) 4-hour-stressed group. Eosinophils, mast cells CD4(+) CD8(+) T lymphocytes mucosa counted. protein mRNA expressions occludin zonula...
DA-9701 is a novel prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber. This study aimed to evaluate the effect of on stress-induced delay in gastric emptying changes plasma adrenocorticotropic hormone ghrelin levels rats.Changes response different durations stress were evaluated. Gastric was compared between following groups: (i) nonstressed vehicle- or DA-9701-treated group, (ii) mosapride-treated (iii) 2-h stressed (iv) group. Water immersion restraint used as stressor....
Stress is believed to play a role in the pathogenesis of functional gastrointestinal disorders. The aim present study was investigate effect acute auditory stress on gastric motor responses meal healthy subjects.A total eight volunteers (seven men and one woman; median age, 33.4 years [30-35 years]) who had no recurrent symptoms participated prospective, randomized, crossover study. Gastric half-emptying time meal-induced proximal accommodation were measured using scintigraphy under control...
Our study aimed to evaluate the long-term outcomes and risk factors for relapse after anti-tumor necrosis factor (TNF)-α cessation in inflammatory bowel disease (IBD) patients because they are not well established.A retrospective multicenter cohort was conducted involving with Crohn's (CD) or ulcerative colitis (UC) from 10 referral hospitals Korea who discontinued firstline anti-TNF therapy achieving clinical remission.A total of 109 IBD (71 CD 38 UC) a median follow-up duration 56 months...
The role of dietary factors in the pathogenesis irritable bowel syndrome (IBS) is still unclear. aim this study was to compare IgG4 levels common food antigens between patients with IBS and healthy controls.Thirty-two diagnosed as according Rome III criteria (12 diarrhea subgroup; 20 non-diarrhea subgroup) 32 sex age-matched controls participated study. Serum titers 90 foods were measured each subject. number subjects positivity defined cut-off value ≥ 0.7 U/mL compared.Patients had...
It is unclear whether IgG4-related immune responses to food can play a role in the pathogenesis of inflammatory bowel disease (IBD). The aim present study was investigate serum levels IgG4 common antigens patients with ulcerative colitis (UC), Crohn's (CD), and healthy controls.
Crohn's disease (CD) is associated with altered body composition, affecting clinical outcomes. We evaluated the impact of biologics on composition in CD patients.This multicenter longitudinal study across four Korean university hospitals conducted from January 2009 to August 2021 retrospectively reviewed data patients abdominal computed tomography (CT) before and after biologic treatment. Skeletal muscle area (SMA), visceral fat (VFA), subcutaneous (SFA) third lumbar vertebra (L3) CT were...
The quality-of-life of patients with irritable bowel syndrome is low; incorrect diagnosis/treatment causes economic burden and inappropriate consumption medical resources. This survey-based study aimed to analyze the current status treatment examine differences in doctors' perceptions disease, patterns.From October 2019 February 2020, Intestinal Function Research Study Group Korean Society Neurogastroenterology Motility conducted a survey on doctors working primary, secondary, tertiary...
Long-term immunosuppressive therapies used to treat inflammatory bowel disease (IBD) are associated with an increased risk of infections, many which can be prevented by vaccination. We assessed physicians' current approaches and clinical practices regarding vaccinations for IBD patients in different Asian countries/regions.An internet-based survey was conducted among members the Organization Crohn's Colitis from September 2020 November 2020. The questionnaire consisted 2 parts covering...
Although surveillance endoscopy is recommended after the treatment of a benign gastric ulcer in Korea, improved survival, secondary to an endoscopic follow-up strategy, controversial. Thus, aim this study was understand results and individualize by analyzing known risk factors for cancer.In total, 599 (M:F=424:175, median age=55.4 years) patients who were diagnosed with underwent between January 2003 August 2014 retrospectively enrolled study. The final analyzed.Multivariate analysis data...