- Aldose Reductase and Taurine
- Pancreatic function and diabetes
- Toxoplasma gondii Research Studies
- Clinical Nutrition and Gastroenterology
- Bioenergy crop production and management
- Cytomegalovirus and herpesvirus research
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Genetic Syndromes and Imprinting
- Heme Oxygenase-1 and Carbon Monoxide
- Child Nutrition and Water Access
- Neuroscience and Neuropharmacology Research
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Gut microbiota and health
- HIV Research and Treatment
- Polyamine Metabolism and Applications
- Memory and Neural Mechanisms
- Ferroptosis and cancer prognosis
- Kruppel-like factors research
- Retinal Development and Disorders
North China University of Science and Technology
2025
Shenyang Agricultural University
2019-2023
Beijing University of Agriculture
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Trinity Health
2020
Howard Hughes Medical Institute
2003
Toxoplasma gondii is a unicellular protozoan parasite of the phylum Apicomplexa. The repeatedly goes through cycle invasion, division and induction host cell rupture, which an obligatory process for proliferation inside warm-blooded animals. It known that biology controlled by variety mechanisms ranging from genomic to epigenetic transcriptional regulation. In this study, we investigated global protein posttranslational lysine crotonylation 2-hydroxyisobutyrylation two T. strains, RH ME49,...
Abstract The biology of Toxoplasma gondii, the causative pathogen one most widespread parasitic diseases (toxoplasmosis), remains poorly understood. Lactate, which is derived from glucose metabolism, not only an energy source in a variety organisms, including T. but also regulatory molecule that participates gene activation and protein function. Lysine lactylation (Kla) type post-translational modifications (PTMs) has been recently associated with chromatin remodeling; however, Kla histone...
Diarrhea in piglets is one of the most important diseases and a significant cause death piglets. Preliminary studies have confirmed that taurine reduces rate index diarrhea induced by LPS. However, there still lack relevant information on specific target mechanism action taurine. Therefore, we investigated effects growth barrier functions intestine, microbiota composition, metabolite composition Eighteen male weaned were randomly divided into CON group (basal diet + standard saline...
The effect of taurine (TAU) as a specific regulatory mediator on pancreatic function in obese rats induced by high-fat-high-glucose (HFHG) diet was investigated. We fed male Sprague-Dawley under different conditions, namely the control, HFHG, TAU, and HFHG + TAU treatment groups for 4 months. Compared with group, supplementation significantly reduced malondialdehyde levels increased superoxide dismutase, total antioxidant capacity, glutathione rat pancreas. In addition, decreased level...