A5100349891- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Prostate Cancer Diagnosis and Treatment
- RNA Research and Splicing
- Augmented Reality Applications
- RNA modifications and cancer
- Boron Compounds in Chemistry
- Advanced X-ray and CT Imaging
- Brain Metastases and Treatment
- Advanced Neural Network Applications
- MicroRNA in disease regulation
- Radiation Dose and Imaging
- Advanced Proteomics Techniques and Applications
- Molecular Biology Techniques and Applications
- Prostate Cancer Treatment and Research
Fox Chase Cancer Center
2004-2023
Soochow University
2022
Second Affiliated Hospital of Soochow University
2022
Shanghai Institute of Pharmaceutical Industry
2019
Wenzhou Medical University
2008
First Affiliated Hospital of Wenzhou Medical University
2008
This paper investigates the clinical significance of real-time monitoring intrafractional prostate motion during external beam radiotherapy using a commercial 4D localization system. Intrafractional was tracked 8,660 treatment fractions for 236 patients. The following statistics were analyzed: 1) percentage in which shifted 2-7 mm certain duration; 2) proportion entire tracking time 2-7mm; and 3) each minute shift exceeded mm. ten patients exhibiting maximum intrafractional-motion patterns...
The purpose of this work is to prospectively assess the setup accuracy that can be achieved with a stereotactic body localizer (SBL) in immobilizing patients for intensity‐modulated radiotherapy (IMRT) prostate cancer. By quantifying important factor and target mobility SBL, we expect provide guideline selecting planning volume margins treatment planning. We analyzed data from 40 computed tomography (CT) studies (with slice thickness 3 mm) involving 10 Each patient had four sets CT scans...
A 3D treatment-planning system (TPS) for stereotactic intensity-modulated radiotherapy (IMRT) using a micro-multileaf collimator has been made available by Radionics. In this work, we report our comprehensive quality assurance (QA) procedure commissioning TPS. First, the accuracy of stereotaxy established with body frame was checked to ensure accurate determination target position within planning system. Second, CT-to-electron density conversion curve used in TPS fitted site-specific...
The purpose of this work is to prospectively assess the setup accuracy that can be achieved with a stereotactic body localizer (SBL) in immobilizing patients for intensity-modulated radiotherapy (IMRT) prostate cancer. By quantifying important factor and target mobility SBL, we expect provide guideline selecting planning volume margins treatment planning. We analyzed data from 40 computed tomography (CT) studies (with slice thickness 3 mm) involving 10 Each patient had four sets CT scans...
Ghrelin (GHRL) is a polypeptide that can specifically bind to the growth hormone secretagogue receptor (GHSR). The expression of GHSR significantly different in normal and prostate cancer (PC) tissues humans. It important find an effective diagnostic method for diagnosis prognosis invasive PC/neuroendocrine (NEPC).GHRL mRNA levels were determined by quantitative real-time polymerase chain reaction PC tissues. GHRL proteins was assessed Western blot assay immunohistochemistry. A probe...
Transmembrane-4 L Six Family member 1 (TM4SF1) belongs to a family of integral membrane proteins implicated in cell growth and tumor progression. Glioma is the most common aggressive malignant brain adults. In this study, we showed that TM4SF1 was highly expressed glioma tissues lines. The expression levels were negatively correlated with patients' survival rates. Silencing by RNA interference inhibited proliferation, migration, invasion cells. Moreover, silencing induced cycle arrest early...
Purpose: A novel rotating gamma stereotactic radiosurgery (SRS) system (Galaxy RTi) with real-time image guidance technology has been developed for high-precision SRS and frameless fractionated radiotherapy (SRT). This work investigated the dosimetric quality of Galaxy by comparing both machine treatment parameters plan dosimetry those widely used Leksell Gamma Knife (LGK) systems SRS. Methods: The RTi uses 30 cobalt-60 sources on a gantry to deliver non-coplanar, non-overlapping arcs...