- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide Residue Analysis and Safety
- Antibiotics Pharmacokinetics and Efficacy
- Metabolomics and Mass Spectrometry Studies
- Analytical chemistry methods development
- Toxic Organic Pollutants Impact
- Pharmacological Effects and Assays
- Advanced Chemical Sensor Technologies
- Antibiotic Resistance in Bacteria
- Water Treatment and Disinfection
- Aquaculture disease management and microbiota
- Spectroscopy and Chemometric Analyses
- Chemistry and Chemical Engineering
- Gut microbiota and health
- Dye analysis and toxicity
- Analytical Methods in Pharmaceuticals
- Food Safety and Hygiene
- Advanced oxidation water treatment
- Food Waste Reduction and Sustainability
- Analytical Chemistry and Chromatography
- Isotope Analysis in Ecology
- Odor and Emission Control Technologies
- Microbial infections and disease research
- Effects and risks of endocrine disrupting chemicals
- Bee Products Chemical Analysis
Centre Hospitalier de Fougères
2017-2024
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2015-2023
European Union
2015
Institut Agro Rennes-Angers
2013
Institut de Recherche en Santé, Environnement et Travail
2010-2012
École des Hautes Études en Santé Publique
2008-2012
Département Santé des Plantes et Environnement
2012
The chemical burden on the environment and human population is increasing. Consequently, regulatory risk assessment must keep pace to manage, reduce, prevent adverse impacts environmental health associated with hazardous chemicals. Surveillance of chemicals known, emerging, or potential future concern, entering environment-food-human continuum needed document reality risks posed by ecosystem from a one perspective, feed into early warning systems support public policies for exposure...
The occurrence of 20 human pharmaceutical compounds and metabolites from 10 representative therapeutic classes was analysed resource drinking water in two catchment basins located north-west France. 98 samples were 63 stations (surface produced surface water). Of the selected, 16 quantified both water, with 22% values above limit quantification for 14% Psychostimulants, non-steroidal anti-inflammatory drugs, iodinated contrast media anxiolytic drugs main detected water. results close to...
The valorization of poultry byproducts, like feathers (processed to feather meal), in animal feed could contribute the presence veterinary drugs, including antibiotics. An study was carried out fate sulfadiazine, trimethoprim, and oxytetracycline feathers, plasma, droppings broiler chickens. Cage floor housing, different from current farm practices, were studied. Samples analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). A longer antibiotics observed compared with...
Although antimicrobials are generally found in trace amounts meat, the human health risk they bear cannot be ignored. With ultimate aim of making a better assessment consumer exposure, this study explored effects pan cooking on sulfonamides and tetracyclines meat. Screening these cooked meat was first performed by European Union Reference Laboratory basis HPLC-MS/MS analyses. A proof concept approach using radiolabeling then carried out most cooking-sensitive...
Poultry feathers are nowadays partially re-introduced into the animal food chain and environment. They valorised by their transformation feather meal in order to be used as fertilisers agriculture but also feed (in particular, pet fish feed). However, unlike producing animals for humans, from poultry not subject a ban or regulatory limits on presence of antibiotic residue after veterinary treatment. Feathers could therefore potential reservoir residues, unintentionally exposing environment...
Rationale This paper investigates the validity of transfer a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for determination veterinary medicinal products in honey and compares it with an LC/linear ion trap/Orbitrap method. A descriptive statistical approach was used order to assess whether such would succeed or fail. is based on simultaneous evaluation trueness intermediate precision each compound at 95% interval confidence both analytical techniques. Methods Two grams...
Salmonella is the most relevant foodborne zoonotic agent found in swine, and its presence French herds significant. Its carriage asymptomatic, which makes it difficult to detect during rearing, thus increasing risk of on pork meat. Studies have shown that enteric infection animals could be associated with changes serum metabolome composition, through immune response or digestive microbiota composition. We hypothesized these composition used as markers for detection asymptomatic infected by...