A5039026260- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Bladder and Urothelial Cancer Treatments
- Radiopharmaceutical Chemistry and Applications
- Oral health in cancer treatment
- Lung Cancer Treatments and Mutations
- Management of metastatic bone disease
- Medical Imaging Techniques and Applications
- Urologic and reproductive health conditions
- Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Urinary Bladder and Prostate Research
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Hepatocellular Carcinoma Treatment and Prognosis
- Brain Metastases and Treatment
- Effects of Radiation Exposure
- Salivary Gland Tumors Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Nanoplatforms for cancer theranostics
- Advances in Oncology and Radiotherapy
UPMC Hillman Cancer Center
2014-2024
University of Pittsburgh
2010-2024
University of Pittsburgh Medical Center
2007-2024
University Vascular Associates
2023
University of Virginia
2017-2022
University of Virginia Medical Center
2022
University of Iowa Hospitals and Clinics
2020
Shadyside Hospital
2018
The Alfred Hospital
2014
Sparrow Health System
2013
Purpose We incorporated cetuximab, a chimeric monoclonal antibody against the epidermal growth factor receptor (EGFR), into induction therapy and subsequent chemoradiotherapy of head neck cancer (HNC). Patients Methods with locally advanced HNC, including squamous undifferentiated histologies, were treated docetaxel 75 mg/m 2 day 1, cisplatin cetuximab 250 days 8, 15 (after an initial loading dose 400 ), termed TPE, repeated every 21 for three cycles, followed by radiotherapy concurrent 30...
Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on field strength tissue properties. These characteristics are organ-dependent, affecting outcomes. This study characterizes relevant properties improve planning outcome predictions for...
Abstract Objective: To determine whether combined positron emission tomography and computed (PET‐CT) may be of value in deferring planned neck dissections for patients with advanced head squamous cell carcinoma (HNSCC). Study Design: Observational study de novo cervical ≥N2 regional spread HNSCC a tertiary care academic medical center. Methods: Forty‐three were identified who underwent post‐treatment PET‐CT within 6 months completing neoadjuvant chemotherapy radiation therapy (CRT). The was...
Background: examine presentation and outcomes of sinonasal squamous cell carcinoma (SCC). Methods: A retrospective study utilizing the National Cancer Database, 2004 to 2015. The population included adult patients diagnosed with primary SCC. Results: total 537 were included. mean age was 62.6 ± 12.7 years. median follow-up time 35.6 months (interquartile range: 8.6-55.9). histological variants identified are: (i) 66.7% keratinizing SCC, (ii) 21.6% non-keratinizing (iii) 8.0% papillary (iv)...
Mucositis and dysphagia are common complications of chemoradiotherapy (CRT) for head neck cancer that may necessitate nutritional support with a gastrostomy tube (G-tube).We reviewed records patients who underwent completed CRT, which included at least one traditional chemotherapeutic, previously untreated cancer. G-tubes were placed as needed. The timing duration G-tube placement treatment-related risk factors long-term use analyzed.A total 91 consecutive received 68 primary 23...
Objectives To evaluate patient-reported quality-of-life (QOL) domains in patients with head and neck cancer (HNC) treated intensity-modulated radiotherapy (IMRT); specifically time-based QOL changes compared baseline correlation independent variables. Methods Between January 2002 August 2006, we prospectively administered the University of Washington Quality Life-Revised assessment to 143 primary HNC IMRT investigate impact treatment on 12 domains. We analyzed 108 more than 6 months...
Patients treated with chemoradiotherapy (CRT) for head and neck cancers often require feeding tubes (FTs) due to toxicity. We sought identify factors associated a prolonged FT requirement.We retrospectively reviewed 80 patients CRT cancers. The pharyngeal constrictors (PCs), supraglottic larynx (SGL), glottic (GL) were contoured the mean radiation doses volumes of each receiving >40, 50, 60, 70 Gy (V40, V50, V60, V70) determined.A total 33 required either before or during course CRT. Fifteen...
6002 Background: We incorporated E, a chimeric IgG1 monoclonal antibody against the epidermal growth factor receptor, into induction therapy and subsequent chemoradiotherapy of HNC. Methods: Patients (pts) had previously untreated, stage III/IV squamous cell or undifferentiated carcinoma HN, ECOG PS 0–1, adequate laboratory parameters. Induction consisted T 75 mg/m² day 1, P E 250 days 1,8, 15 (after an initial dose 400 on cycle 1), repeated every 21 x 3 cycles, with prophylactic...